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Physiology Lab midterm
UTSA Advanced Physiology Lab midterm review
110
Physiology
Undergraduate 4
10/14/2010

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Term
pulse
Definition
time from which data leaves baseline to the time where it comes back to baseline
Term
Plethysmograph
Definition
measures the pressure exerted against the walls of the vessels in your finger
Term
duration (seconds)
Definition
time interval from the beginning of one pulse to the end of the same pulse
Term
Magnitude (mV)
Definition
maximum voltage on one pulse - minimum voltage on same pulse
Term
Frequency (1/s) or (Hz)
Definition
number of cycles/ time
Term
cycle
Definition
the time from the beginning of one pulse to the beginning of the next
Term
diffusion
Definition
random movement of molecules down a concentration gradient from an area of high solute concentration to an area of low solute concentration
Term
Osmosis
Definition
a type of diffusion involving the movement of a solvent (H2O) across a semi permeable membrane.
Term
Osmotic pressure formula
Definition
pi = iRT(C1-C2). i is total number of ions, r is gas constant (.0821), T is temp in K, and C1 is concentration gradient inside whatever, C2 is concentration gradient of outside
Term
Osmole
Definition
the number of particles in a solution expressed as osmoles/L
Term
osmolarity
Definition
molarity * # of ions
Term
Osmotic pressure
Definition
the tendency of water to flow osmotically toward a solution. the greater the osmolarity of a solution, the greater will be the tendency for water to move across a semipermeable membrane towards that solution
Term
iso-osmotic
Definition
two solutions separated by a semipermeable membrane are iso-osmotic to each other if they have the same osmotic pressure or number of solute particles
Term
hyperosmotic
Definition
if one solution has a greater osmotic pressure than the other solution- it is hyper to the other solution
Term
hypo-osmotic
Definition
if it has a lower osmotic pressure then it is hypo to the other solution
Term
tonicity
Definition
the ability of an extracellular solution to cause changes in the size and shape of a cell
Term
isotonic
Definition
no shape change in cell
Term
hypertonic
Definition
cell looses water and shrinks - becomes crenated
Term
hypotonic
Definition
cell gains water and swells, can cause hemolysis - where it bursts and loses its contents
Term
turbidity
Definition
fogginess - the more opaque - the more severe the hemolysis is
Term
endocrine glands
Definition
do not have a duct system - release hormones directly into the blood
Term
exocrine glands
Definition
hace a duct - from a gland to its target organs
Term
Hormone
Definition
a chemical messenger secreted by cells into the etracellular fluids that regulates the metabolic functions of other cells in the body. causes a change in physiology to the cells that help maintain a homeostatic state.
Term
steroid hormones
Definition
they are synthesized from cholesterol
Term
Polypeptide
Definition
derived from amino acids
Term
Tyrosine derivatives hormones
Definition
derived from amino acid tyrosine - also requires a mineral to be derived
Term
Receptors for steroids
Definition
located inside the cell
Term
receptor for polypeptide hormones
Definition
embedded on the plasma membrane - site is extracellular
Term
Adenelate cyclase
Definition
enzyme used to convert ATP to cAMP - becomes second messenger
Term
transcription happens?
Definition
inside the nucleus
Term
translation happens ?
Definition
outside the nucleus - need free ribosomes
Term
Anterior lobe of Pituitary
Definition
Pars distalis - furthest from midline. Pars intermedia - middle, pars Tuberalis - stalk of gland
Term
Posterior lobe of pituitary
Definition
Pars nervosa
Term
TSH - thyroid stimulating hormone
Definition
increased thyroid hormone secretion
Term
ACTH Adrenocorticotropic
Definition
increased glucocorticoid secretion
Term
FSH Follicle stimulating hormone
Definition
follicle maturation and estrogen
Term
LH - lutenizing hormone
Definition
ovulation and testosterone synthesis
Term
PRL - prolactin
Definition
milk synthesis in lactating women
Term
GH - growth hormone
Definition
also called somatostatin: increased growth in tissues, amino acid uptake, protein synthesis, and glycogen and glucose levels
Term
MSH - melanocyte-stimulating hormone
Definition
increases the production of melanin in melanocytes
Term
Oxytocin
Definition
stimulates uterine contractions and milk ejection from the mammary glands
Term
ADH - Antidiuretic Hormone - Vasopressin
Definition
elevates B/P and promotes reabsorption of H2O by the kidney
Term
Parathyroids
Definition
separate glands that reside within the thyroid
Term
T3 - Triiodothyronine
Definition
regulates body metabolism and bone growth; development of and maturation of brain and nervous system. Cretinism and hypothyroidism
Term
T4: tetraiodothyronine
Definition
same as T3
Term
Calcitonin (also thyroid)
Definition
decrease calcium levels in the blood. secreted from parafollicular cells that surround the thyroid cells
Term
parathyroid hormones
Definition
increase blood Ca levels
Term
3 layers of the adrenal cortex
Definition
Zona glomerulosa: produces mineralocorticoids - maintains water and electrolyte balances. Zona fasciculata: produces gulcocorticoids - regulates glucose in the body. Zona reticularis: produces adrenal sex hormones - also known as androgens testosterone and estrogen.
Term
Aldosterone
Definition
ad. cortex - principle mineralocorticoids - secreted in response to Na deprivation Z.G.
Term
cortisol
Definition
stimulated by ACTH Z.F.
Term
Androgen
Definition
Testosteron Z.R.
Term
2 hormones of the adrenal medulla - Epi and Norepi
Definition
Epinephrine: released in response to environmental stressors. Norepi: increases B/P; constricts pupils
Term
Islets of Langerhans
Definition
cells in the pancreas that are in clusters of 3
Term
Alpha cells
Definition
secrete glucagon to increase glucose levels in blood
Term
Beta cells
Definition
secrete insulin to uptake excess glucose from the bloodstream
Term
Delta Cells
Definition
secrete somatostatin which will either stimulate glucagon to raise glucose levels or insulin to decrease them
Term
gluconeogenesis
Definition
formation of glucose from CHO, FAT, and PRO -occurs between meals
Term
glycogenolysis
Definition
liver makes glucose out of glycogen stored in the liver - this kicks in with a stressor
Term
catabolism
Definition
break down of proteins
Term
anabolism
Definition
build up of proteins
Term
oligodendrocytes
Definition
produce myelin in the CNS
Term
Schwann cell
Definition
produce myelin in the PNS
Term
Astrocytes
Definition
line capillaries of the brain; control the ionic environment around neurons; responsible for blood-brain barrier
Term
ependymal:
Definition
line brain and CNS; active role in synthesizing cerebral spinal fluid
Term
microcytes:
Definition
support the adventitial (outermost) layer of the brain; are a special type of macrophage that help protect the CNS by engulfing invading microorganisms and dead neural tissues
Term
satellite cells
Definition
found closely associated with schwann cells; thought to play a role in controlling the chemical environment of neurons
Term
neuroglia (glial cells)
Definition
provide structure and support to the neuron
Term
translation happens?
Definition
in the axon hillock
Term
Myelin Sheath
Definition
cylindrical cells covering the axon of the cell that aid in insulation and conduction. surrounds axon for rapid conductance; energy efficient
Term
nodes of ranvier
Definition
spaces between myelin sheaths where action potentials "jump" between nodes for faster impulse movement down the axon
Term
resting membrane potential
Definition
- 70 mV
Term
threshold potential
Definition
-55 mV
Term
depolarization
Definition
happens when AP goes - Na rushes in and depolarizes the inside - switches charge from - to +... +40 is max depol
Term
repolarization
Definition
happens when it dips back down to baseline - Na channels close, K channels open so there will be an efflux out of the cell - takes it back down to -70 mV
Term
hyperpolarization
Definition
goes down past -70 mV because K channels are slow so too much leaves = it fixes it self and comes back to resting though
Term
Sodium Potassium ATPase pumps
Definition
3 Na out, 2 K in - that is how -70 is maintained
Term
Presynaptic cleft
Definition
AP reaches presynaptic terminal, voltage gated Ca channels open, influx of Ca occurs, synaptic vesicles fuse with membrane
Term
Synaptic cleft
Definition
neurotransmitters are released into the synaptic cleft and diffuse to the postsynaptic membrane
Term
Post Synaptic cleft
Definition
neurotransmitter binds to neuroreceptors on the postsynaptic membrane, this causes Na channels to open flow into postsynaptic neuron
if threshold is reached, action potential is initiated - within the synaptic cleft enzymes break down leftover neurotransmitter
Term
Effects of Ether
Definition
general anesthetics - restricts AP from reaching threshold because the K gates open and it leaks out - causing the cell to hyperpolarize
Term
Effects of Lidocaine
Definition
local anesthetics - blocks the Na channels - prevents flow of Na into the cell - so threshold cannot be reached, no AP
Term
Effects of Curare
Definition
snake venoms - blocks receptors on postsynaptic cell APs cant continue to destination - muscles don't contract - paralysis occurs
Term
Effects of Curare
Definition
snake venoms - blocks receptors on postsynaptic cell APs cant continue to destination - muscles don't contract - paralysis occurs
Term
Absolute Refractory Period
Definition
second AP cannot be generated due to all the Na gates being closed but inactive K gates are open
Term
Relative Refractory Period
Definition
second AP can be generated; Na channels are closed, K channels are open; action potential will always be lesser in magnitude (during hyperpolarization)
Term
Acetylcholine
Definition
neurotransmitter - elicits an effect on the heart
Term
Parasympathetic ganglia
Definition
Pre is long, post is short - ACH is the neurotransmitter
Term
Sympathetic Ganglia
Definition
pre is short, post is long - catecholemines is epi and nore - they increase HR and force of contractions
Term
Cholinergic
Definition
any neuron that uses ACH as their operating neurotransmitter
Term
Adrenergic
Definition
uses Epi and Norepi (adrenaline) as their operating neurotransmitter
Term
Characteristics of the Parasymp
Definition
ganglia located close to the effector organ and far from spinal cord, motor neurons exit the brain and sacral regions (craniosacral)
Term
Characteristics of they Symp
Definition
ganglia located far from effector organ and closer to the spinal cord, motor neurons exit the thoracic and lumbar regions of the spinal cord (throacolumbar)
Term
Muscarinic Receptor
Definition
stimulatory effects; named because of their selective stimulation by muscarine which is derived from the mushroom - a type of cholinergic receptor
Term
Nicotinic Receptor
Definition
stimulatory/inhibitory effects; derived from nicotine
Term
ACH
Definition
Ach decreases H.R. - it delays transmission of the impulse, AP into the ventricles and decrease the rhythm rate into the SA node. Cells in the SA node initiate their own depolarization without the CNS input. Ach increases permeability of the SA node to K ions - makes them leaky - causes hyperpolarization - threshold is farther away now
Term
Heart conduction system
Definition
AV node - sends signals to bundles of HIS - they then split and go to both ventricles - purkinje fibers carry out the last signal transduction
Term
Epinephrine
Definition
an andrenergic agonist which binds to adrenergic receptors, increases the HR and strength of contraction (two types of receptors - alpha and beta. Epi binds to beta receptors on the Heart thereby increasing the heart rate
Term
therapeutic uses of Epi
Definition
Lidocain - local anesthetic - constrict peripheral blood vessels - restricts blood flow to area. Anaphylactic shock and cardiac arrest
Term
Pilocarpine
Definition
direct actin cholinergic agonist which decreases HR by directly acting on the receptor - actss the same as acetylcholine. Therapeutic uses - Xerostomia (dry mouth), glaucoma and cystic fibrosis
Term
Digitalis
Definition
strengthens the force of the Heartbeat by increasing the amount of Ca in the cardiocytes - it binds to Na and K receptors and stops it from leaving the cell - as Ca builds up in the class, it causes a stronger heartbeat. It is used therapeutically for Atrial Arrhythmias and Congestive Heart Failure
Term
Atropine
Definition
a cholinergic antagonist which blocks the ACh receptor causing increased sympathetic tone thus indirectly increasing the heart rate. antagonist at the muscarinic receptor - it indirectly increases Heart Rate
Term
mydriasis
Definition
pupil dilation. two ways to cause mydriasisBlock the action of Ach on the sphincter pupillage, increases noradrenaline on the dilator pupillae
Term
when ciliary muscles relax
Definition
the lens assumes more flattened shape and is less convex
Term
when ciliary muscles contract
Definition
the lens assumes a more spherical shape - muscle fibers relaxes the ligament of lens capsule
Term
diopter
Definition
1/focal length
Term
the shorter the focal length
Definition
the higher the diopter - more concave lens has a decreased focal length
Term
two muscles controlling the blink reflex
Definition
orbicularis oculi and levator palpebrae - both innervated by facial nerve VII
Term
miosis
Definition
abnormal/fixed constriction of pupils (pin point pupils)
Term
presbyopia
Definition
decreased elasticity of the lens
Term
reaction times
Definition
auditory - 150, visual - 190 ms
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