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In carnivores, digestion is mainly |
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Definition
enzymatic and microbial digestion is minimal |
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Transit time is _______ in herbivores than carnivores. |
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Those with simple stomachs usually digest |
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Ruminants and horses eat plant matter which is considered |
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Definition
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Continual grazing of horses and ruminants is required due to |
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Definition
the low energy content of plant matter and for continual musculature contraction of the digestive tract |
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Term
How do ruminants maintain blood glucose concentration considering very little blood glucose is absorbed under natural fermentative conditions? |
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Definition
glucose is produced in the liver by short chain fatty acids |
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Term
Fermantation and SCFA metabolism is ______ efficient than direct absorption of glucose from the gut. |
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In ruminants, what is formed and often utilized by microorganisms to for microbial protein? |
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The major end product of carbohydrate digestion in the horse is ________ |
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Definition
epithelium, lamina propria, muscularis mucosa |
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Definition
connective tissue, vessels, nerves - submucosal plexus |
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Definition
circular muscle and longitudinal muscle |
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Definition
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Two ganglia that have plexuses in the intestinal wall are |
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Definition
submucosal plexus and the myenteric plexus |
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Term
The myenteric plexus lies between the |
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Definition
circular and longitudinal muscle layers |
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Term
Circular muscle _______, while longitudinal muscle ______ __________. |
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Definition
constricts, runs lengthwise |
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Term
The myenteric and submucosal plexuses make up the |
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Definition
ENS - enteric nervous system |
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Term
Neural control of gut function is controlled by the _____ and _____. |
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Definition
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In the ruminant, urea - non protein nitrogen can be utilized to synthesize _______ _______ and takes place in the __________. |
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Definition
microbial protein, forestomach |
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Term
Why are horses less efficient at digestion than ruminants? |
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Definition
Passage rates through the large intestine are faster in the horse than in ruminants meaning there is less time spent digesting, resulting in loss of efficiency |
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Term
Layers of the intestinal wall in their order of appearance from lumen to serosa. |
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Definition
Lumen, mucosa, submucosa, muscularis externa, serosa |
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Term
The submucosal plexus lies between the |
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Definition
muscularis externa and the submucosa |
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Term
What is the orientation of the two smooth muscle layers? |
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Definition
The innermost layer is circular and the outermost layer is longitudinal |
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Term
What are the receptors for preganglionic neurotransmitters? |
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Definition
nicotinic/cholenergic receptors for ACh |
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Term
What are the receptors for postganglionic neurotransmitters? |
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Definition
adrenergic(S), muscarinic(PS) for Ach, as well as somatostatin, neuropeptide Y (NPY) receptors |
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Term
What is the route and potential for sympathetic sensory (afferent) neurons? |
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Definition
the fibers synapse at the dorsal root ganglion in the spinal cord |
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Term
Where do parasympathetic, preganglionic neurons synapse? What is the major transmitter at this location? |
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Definition
at the ganglion of the myenteric and submucosa plexuses and use ACh as their main neurotransmitter |
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Term
Can basic peristalic reflex take place with all CNS connections severed? |
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Definition
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Term
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Definition
increases contractile activity and secretion |
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Term
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Definition
decreases contractile ability, motility, secretions, blood flow, and can also can inhibit Ach release |
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Term
Name two ways in which adrenergic stimulation can exert its inhibitory effects |
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Definition
by inhibiting Ach release and can inhibit epithelium and muscle directly |
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Term
What are the ENS neurons that contain inhibitory substances known as? |
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Definition
NANC – noncholinergic, nonadrenergic inhibitory neurons |
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Definition
intestinal obstruction caused by inhibition of motor activity (hypomotility) can be due to surgery, peritonitis, or mechanical obstruction |
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Name the reflex associated with simple obstruction |
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Definition
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Definition
when an obstruction occurs motility is increased cranially while motility is decreased caudally from the point of obstruction; cholinergic nerves are involved as well as NANC neurons |
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What is the response to persistent obstruction and finally, severe distention? |
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Definition
longer segments of intestine become inhibited until complete paralysis of the intestinal tract |
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Term
What substances released from postganglionic adrenergic and enteric nerves induce inhibition? |
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Definition
NPY - neuropeptide Y and NO - nitrous oxide |
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Term
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Definition
arise from neural crest of embryo and distribute thorughout GI to synthesize peptide hormones and amines |
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Term
Cells that secrete gastrin, secretin, and CCK are located |
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Definition
in the stomach and proximal small intestine |
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Term
How are the enteroendocrine secretions transmitted? |
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Definition
secreted in blood or from cell to immediate vicinity |
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Term
CCK, gastrin, and secretin |
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Definition
initiate gastric and intestinal phases of digestion |
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Term
How does the location of cells secreting enteroglucagon and peptide YY correlate with their function? |
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Definition
located in the distal small intestine, function as the “ileal brake” that slows gastric emptying and small intestinal transit, promoting increased small intestinal absorption. |
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Term
Systemic hormones have potent effects on |
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Definition
water and electrolyte transport in gut and kidney |
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Term
Resident cells in lamina propria are capable of |
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Definition
secreting basal amounts of soluable mediators to perform "housekeeping" functions and have local regulatory action on motor, secretory, and barrier function |
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Term
Prostaglandins and nitrous oxide |
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Definition
protect and maintain mucosal epithelial barrier and mucosal blood flow |
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Term
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Definition
mediate cell to cell communication, mostly between leukocytes and stimulate cell and mucosal growth |
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Term
What are the 4 growth factors present GI tract? |
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Definition
Epidermal growth factor, transforming growth factor, insulin-like growth factor, and fibroblast growth factor |
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Definition
are secreted by mast cells and have direct action on smooth muscle cell contractibility and epithelial cell electrolyte secretion |
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Term
Micro amounts of hydrogen peroxide secreted by phagocytes weakly stimulate epithelial cells to |
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Definition
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Definition
receptors binding to transmitters due to degree of attraction |
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ability to activate the intracellular machinery that mediates the physiological response |
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Definition
having both affinity and efficacy |
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Definition
react with receptors but lack efficacy |
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Definition
remain on exterior of cell |
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activate intracellular machinery inside the cell |
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Term
Hormones and mediators are recognized by receptors that trigger release of |
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