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Physiology Final BSC2086 Tests 1-3
TCC- Dr. Momeny
184
Physiology
Undergraduate 2
12/09/2012

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Term
Autonomic nervous system preganglionic fibers leave the CNS and then synapse on?
Definition
ganglionic neurons
Term
Which areas of the brain exert control over the autonomic nervous system?
Definition
hypothalamus, Pons, Medulla
Term
Cell body of preganglionic neurons of the sympathetic division are located in the
Definition
lateral gray horn of the spinal cord
Term
Clusters of ganglionic sympathetic neurons lying along either side of the spinal cord are called sympathetic ________ ganglia.
Definition
chain
Term
During sympathetic activation, __________ occurs.
Definition
elevated heart rate
elevated blood pressure
sweating
elevated blood glucose
Term
The celiac, superior mesenteric and inferior mesenteric ganglia are collectively called _________ ganglia.
Definition
collateral
Term
A person confronted by a dangerous dog. His heart begins to race and beat strongly, his pupils dilate, and his hairs stand up. There signs are the result of
Definition
sympathetic activation
increased levels of epinephrine in the blood
increased activity of autonomic centers in the hypothalamus
the "flight or fight" response
Term
The statement "its ganglia are usually near or within the end or" is
Definition
true only for the parasympathetic nervous system
Term
The statement "its postganglionic axons always use acetylcholine as the neurotransmitter" is
Definition
true only the the parasympathetic nervous system
Term
Nicotinic receptors
Definition
respond to acetylcholine
Term
The statement "preganglionic axon terminals release acetylcholine" is
Definition
true for both parasympathetic and sympathetic nervous system
Term
Dual innervation refers to an organ receiving
Definition
both sympathetic and parasympathetic innervation
Term
What are adrenergic receptors?
Definition
alpha 1 & 2
beta 1 & 2
Term
Craniosacral division is another name for the
Definition
parasympathetic division of the ANS
Term
Which structures are innervated by the celiac ganglion?
Definition
stomach
liver
pancreas
spleen
Term
The _______ division of the ANS is said to function during the "rest & digest"
Definition
parasympathetic
Term
Parasympathetic Functions include:
Definition
constriction of the pupils
stimulation of urination
stimulation of defecation
Term
The vagus nerve is the major source of parasympathetic output?
True or false?
Definition
True
Term
The suprarenal medullae secrete
Definition
norepinephrine
Term
Stimulation of the alpha 1 adrenergic receptors by norepinephrine results in
Definition
release of calcium ions from intracellular stores
Term
A certain drug decreases heart rate by blocking receptors of cardiac pacemaker cells. This drug probably decrease the activity of sympathetic system by binding to _________ receptors.
Definition
beta-1 adrenergic
Term
What structure changes the shape of the lens for far and near vision?
Definition
ciliary body
Term
The transparent portion of the fibrous tunic is the
Definition
cornea
Term
In the human eye, which structure has the highest refraction power
Definition
cornea
Term
An area of the retina that contains only cones and is the site of sharpest vision is the
Definition
fovea
Term
Which term applies to the term myopia?
Definition
nearsightedness
Term
The cornea is the part of the
Definition
fibrous tunic
Term
The gelatinous material that gives the eyeball its basic shape is the
Definition
vitreous humor
Term
Pupillary muscle groups are controlled by the ANS. Parasympathetic activation causes pupillary__________, and sympathetic activation causes __________.
Definition
constriction

dilation
Term
During accommodation, the ciliary muscle _________ and the suspensory ligaments become _________ which, in turn, cause the lens to become _____________.
Definition
contracts

loose

round
Term
What structure regulates the amount of light that passes to the photoreceptors of the eye?
Definition
iris
Term
The optic disc is a blind spot because
Definition
no photoreceptors located here
Term
When a rod is stimulated by light?
Definition
plasma membrane becomes hyperpolarized
retinal changes from the 11-cis to the 11-trans form
less neurotransmitter is released
cGMP decreases and sodium channels close
Term
The first step in process of photoreception is
Definition
absorption of a photon by a visual pigment
Term
Steps that occur in rods when they are excited by photon of light
Definition
1. Retinal changes from 11-cis form the 11-trans form
2.Opsin activation occurs
3. opsin activates transducin
4.Increased phosphodiesterase breaks down cGMP
5. Membrane sodium channels close
6. Membrane hyperpolarizes and rate of NT's release declines
Term
Statements about the retina?
Definition
Ganglion cells send axons to the brain as cranial nerve II
Axons carrying its output synapse in the thalamus
It has photoreceptors that do no respond to dim light
It has photoreceptors that do no respond to red light
Term
Epithelial Layer of the eye aka
Definition
fibrous tunic
Term
Epithelial Layer of the eye
Definition
consists of the sclera, limbus, and cornea
provides mechanical support and some protection for the eye
contributes optical power
is where extrinsic eye muscles insert
Term
Neural Tunic of the eye
Definition
contains ganglion cells
contains the photoreceptor cells
contains bipolar cells
is the deepest layer of the eyeball
Term
The _________ ear collects sound waves and transmits them to the ___________ ear, which contains auditory ossicles.
Definition
outer

middle
Term
The external acoustic meatus ends at
Definition
tympanic membrane
Term
Sequence of ear?
Definition
tympanum. malleus. incus. stapes. oval window. round window
Term
The vibrations received by tympanic membrane are transferred to the oval window by the
Definition
auditory ossicles
Term
The middle ear communicates with the nasopharynx through the
Definition
auditory tube
Term
The function of the auditory tube is to
Definition
equalize air pressure on both sides of the tympanic membrane
Term
The structure that forms the "roof" of the organ of Corti is the
Definition
tectorial membrane
Term
Gravity and linear acceleration are sensed in the
Definition
saccule and utricle
Term
Bending of stereocilia of the inner ear hair cell results in
Definition
change in the transmembrane potential of the hair cells
Term
Condition in which the lens of the eye lost its transparency is called
Definition
cataract
Term
movement of the endolymph in the semicircular canals
Definition
signals rotational movements
Term
Olfactory receptors send axons through the cribriform plate. They synapse on neurons in the
Definition
olfactory bulb
Term
Olfactory pathways
Definition
they are the only sensory pathways to reach the forebrain w/o first synapsing in the thalamus

information flows to the olfactory cortex, hypothalamus, and limbic system

primary afferents synapse in the olfactory bulb
Term
Olfactory discrimination is due to
Definition
pattern of olfactory receptor activity
Term
Olfactory receptors __________ with age & have _____________ turnover
Definition
decline

considerable
Term
When an odorant binds to its receptor causes activation of adenylyl cyclase
T or F?
Definition
True
Term
Which lingual papillae has the largest number of taste buds
Definition
circumvallate papillae
Term
Taste buds are monitored by which cranial nerves?
2
Definition
facial nerve (VII)
Glossopharyngeal Nerve (IX)
Term
Six Primary Taste sensations
Definition
Sweet
Sour
Salty
bitter
umami
calcium
Term
Sensation that is triggered by chicken broths and parmesan cheese is known as?
Definition
umami
Term
Type of G protein coupled receptor?
taste bud
Definition
sweet
bitter
umami
Term
Water taste receptors are located in the:
Definition
pharynx
Term
Salt taste receptors are ligand ion gated channels and when they open the receptor cell get depolarized.

T or F
Definition
true
Term
Plasma is closet in composition to?
Definition
interstitial fluid
Term
The percent fraction of formed elements relative to whole blood is the:
Definition
hematocrit
Term
The most abundant protein in the blood plasma are
Definition
albumins
Term
Plasma protein essential for blood coagulation is
Definition
fibrinogen
Term
Red blood cell production is regulated by the hormone
Definition
erythropoeitin
Term
Ages and damaged erythrocytes are broken down by macrophages in the
3
Definition
spleen
liver
bone marrow
Term
The waste product of bilirubin is produced from
Definition
heme molecules lacking iron
Term
In adults, erythropoiesis exclusively takes place in
Definition
red bone marrow
Term
____________ are immature erythrocytes that are present in the circulation.
Definition
reticulocytes
Term
The yellow color that is visible in the eyes and skin in jaundice results from
Definition
excessive amounts of bilirubin in the plasma
extensive breakdown of RBC
destruction of hemoglobin
recycling of hemoglobin
Term
The most numerous white blood cells in peripheral circulation are the
Definition
neutrophils
Term
____________ are large phagocytic white cells that spend most of their time outside the blood as fixed and free phagocytic cells.
Definition
monocytes
Term
White blood cells that are increased in allergic individuals are the
Definition
eosinophils
Term
During bacterial infection you would expect to see increased number of
Definition
neutrophils
Term
Function of platelets is to assist in the
Definition
process called hemostasis
Term
______________ involves a cascade of reactions leading to the conversion of fibrinogen to fibrin.
Definition
coagulation
Term
Most of the protein factors that are required for clotting are synthesized by
Definition
the liver
Term
The process of fibrinolysis
Definition
dissolves clots
Term
Vitamin needed for the formation of clotting factors?
Definition
vitamin K
Term
Conversion of fibrinogen to fibrin is catalyzed by the enzyme
Definition
thrombin
Term
The lymphatic system
Definition
helps maintain normal blood volume
eliminates variations in the composition of interstitial fluid
transports lipids from the digestive tract
fights infection
Term
Most of the lymph returns to the venous circulation by way of the
Definition
thoracic duct
Term
The cells responsible for humoral immunity are the ______ cells
Definition
B
Term
The term lymphadenopathy
Definition
chronic or excessive enlargement of lymph nodes
Term
The cells responsible for the production of circulating immunoglobulins are the ______ cells
Definition
plasma
Term
Lymphocytes are produced and stored in:
Definition
thymus
lymphatic nodules
lymph node organs
the spleen
Term
About the lymphocytes, T is to _____ as B is to _____ .
Definition
thymus dependent

bone marrow derived
Term
Lymphatic vessels are located:
Definition
Periphery
Renal arteries
groin
throat
Term
The body's innate defenses include:
Definition
skin
complement
interferon
inflammation
Term
The release of endogenous pyrogen (interleukin-1) by active macrophages would
Definition
produce a fever
Term
Inflammation produces a localized
Definition
swelling
redness
heat
pain
Term
The cells that perform immunological surveillance are the ______ cells
Definition
NK
Term
Adaptive defenses depend on the the activities of the
Definition
lymphocytes
Term
Characteristics of adaptive defenses include
Definition
versatility
tolerance
memory
specificity
Term
Immunity that results from antibodies that pass through the placenta from mother to fetus is called __________ immunity
Definition
naturally acquired passive
Term
Cells that help regulate the immune response are ________ cells
Definition
helper T
Term
When an antigen is bound to a Class I MHC molecule, it can stimulate a __________ cell
Definition
cytotoxic T
Term
Immunoglobulins that are most abundant and are responsible for resistance against many viruses, bacteria, and bacterial toxins are
Definition
IgG
Term
Inappropriate or excessive immune responses to antigens are
Definition
allergies
Term
Stress can affect the immune response by
Definition
depressing the inflammatory response
reducing the number of phagocytes
inhibiting interleukin secretion
increasing the level of glucocorticoids
Term
Blood leaves the right ventricle by passing through the
Definition
pulmonary semilunar valve
Term
Blood returning to the heart from the pulmonary circuit first enters the
Definition
left atrium
Term
Cardiac Muscle cells and skeletal muscle cells differ in a few ways
Definition
Cardiac muscle cells are smaller in size
Cardiac muscle cells have a single, centered nucleus
Cardiac muscle cells branch
Skeletal muscle cells lack intercalated discs
Term
The right atrium receives blood from the
Definition
coronary sinus
superior vena cava
inferior vena cava
systemic circuit
Term
Function of an atrium is to
Definition
collect blood

pump blood to the ventricle
Term
In cardiac muscle, the fast depolarization phase of the action potential is the result of
Definition
increased membrane permeability to sodium ions
Term
The long plateau phase of the cardiac muscle action potential is due to
Definition
calcium channels remaining open
Term
The __________ valve prevents backward flow into the left atrium
Definition
bicuspid
Term
If the pacemaker cells in the SA node become more permeable to potassium ions, the
Definition
heart rate will decrease and cells will hyperpolarize
Term
Depolarization of the ventricles is represented on an EKG by the
Definition
QRS complex
Term
Structural Components of the conducting heart
In order:
Definition
SA node. AV node. AV bundle. bundle branches. purkinje fibers
Term
During the T wave of the EKG, the ventricles are
Definition
both repolarizing and relaxing
Term
Pacemaker cells isolated from the SA node generate action potentials at ______ beats per minute.
Definition
70 - 100
Term
Depolarization of the atria corresponds to the EKG's
Definition
P wave
Term
The first heart rate sound
Definition
AV valve closes
Term
The second heart sound "lub"
Definition
closing of the semilunar valves
Term
Considering the left ventricle, why does isovolumetric ventricular contraction occur during ventricular systole?
Definition
The bicuspid valve needs time to shut before the ventricle can eject blood
Term
The phase in the cardiac cycle when the mitral valve is closed and the aortic valve is open is the
Definition
systolic ejection phase
Term
The heart is innervated by _________ nerves
Definition
both parasympathetic and sympathetic
Term
Stroke volume depends on
Definition
end diastolic volume
the contractility of the ventricle
pressure required to pump blood into the aorta
venous return of blood to the heart
Term
What would cause the stroke volume to increase?
Definition
when diastolic blood pressure is decreased
Term
Cardiac output in increased by
Definition
sympathetic stimulation
Term
If the force of ventricular contraction increases what will happen to the end-systolic volume?
Definition
decrease
Term
End-systolic volume is defined as the
Definition
amount of blood remaining in a ventricle after contraction
Term
Calculate the cardiac output of a patient with a heart rate of 100 bpm and a stroke volume of 75ml?
Definition
7500 ml/min
Term
Functions of the urinary system include
Definition
regulation of blood volume and blood pressure
regulation of plasma concentration of certain ions
helping to stabilize blood pH
conservation of valuable nutrients
Term
Glomerulus is
Definition
knot of capillaries within the renal corpuscle
Term
The urinary system regulates blood volume and pressure by
Definition
adjusting the volume of water lost in urine
releasing erythropoetin
releasing renin
regulating NaCl levels in blood
Term
Urine is carried from kidney to urinary bladder by
Definition
ureters
Term
Blood enters the glomerulus via a blood vessel called
Definition
afferent arteriole
Term
Glomerular (Bowman's) capsule and glomerulus make up the
Definition
renal corpuscle
Term
Region known as the macula densa is part of
Definition
distal convoluted tubules
Term
Cells of the macula densa and juxtaglomerular cells form the
Definition
juxtaglomerular complex
Term
Important function of the kidney
Definition
control of total body water
control of electrolyte composition of the blood
control production of RBC by bone marrow
regulation of blood pressure
Term
Filtration of plasma takes place in the
Definition
renal corpuscle
Term
Efferent arteriole of a nephron divides to form a network of capillaries within the cortex called ___________ capillaries
Definition
peritubular
Term
Primary function of proximal convoluted tubule is
Definition
absorption of ions, organic molecules vitamins, and water
Term
The majority of glomeruli are located in the ________ of the kidney
Definition
cortex
Term
Which of these components are located in the ________ of the kidney
Definition
cortex
Term
__________ __________ are largely confined to the renal medulla.
Definition
collecting ducts
Term
The renal threshold for glucose
Definition
180 mg/dL
Term
Process of filtration is driven by
Definition
blood hydrostatic pressure
Term
What pressures resist glomerular filtration
2
Definition
capsular hydrostatic osmotic pressure
blood colloid osmotic pressure
Term
Ability to form concentrated urine depends on the functions of
Definition
loop of Henle and collecting ducts
Term
mechanism for producing a concentrated urine involves
Definition
secretion of antidiuretic hormone (ADH) by neurohypophysis
aquaporins being inserted into the membranes of the collecting duct cells
high concentration of NaCl in the interstitial fluid that surrounds the collecting ducts
increase in facultative water reabsorption
Term
Thick ascending limb of the nephron loop is almost impermeable to water, but reabsorbs sodium, potassium and chloride ions from the filtrate
Definition
both statements are true
Term
Angiotensin converting enzyme converts angiotensin I to angiotensin II. A drug that inhibits angiotensin converting enzyme (ACE) may lead to
Definition
less secretion of aldosterone
increased urinary loss of sodium
reduction of blood pressure
decreased sodium reabsorption
Term
What undergoes tubular secretion?
Definition
hydrogen ions
Term
What substances are not found in filtrate?
Definition
protein
Term
As filtrate passes through the renal tubules, approx what % is reabsorbed and returned to the circulation?
Definition
99%
Term
In response to increased levels of aldosterone, the kidneys produce
Definition
urine with a lower concentration of sodium ions
Term
Where does countercurrent occur?
Definition
loop of Henle
Term
What area is sensitive to ADH
Definition
distal convoluted tubule and collecting duct
Term
What area is sensitive to aldosterone?
Definition
distal convoluted tubule
Term
The nasal cavity, pharynx and larynx constitute the _________ portion of the airway
Definition
conducting
Term
The respiratory epithelium of conducting airways consists of
Definition
pseudostratified ciliated columnar epithelium
Term
Larynx, trachea, bronchi, and bronchioles make up the
Definition
lower respiratory tract
Term
Inhaling through the nostrils is preferred over the mouth because
Definition
allows for better conditioning of the inhaled air
Term
Functions of the nasal cavity
Definition
filtering air
warming air
humidifying air
Term
Respiratory membrane of the has exchange surfaces consists of
Definition
simple squamous epithelium
Term
Damage to the type II pneumocytes of the lungs would result in
Definition
loss of surfactant
Term
Condition resulting from inadequate production of surfactant and resultant collapse of alveoli is
Definition
respiratory distress syndrome
Term
External respiration involves the
Definition
diffusion of gases between the alveoli and the circulating blood
Term
Boyle's law states that the pressure of a gas is
Definition
inversely proportional to volume of its container
Term
Air moves out of the lungs when the pressure inside the lungs is
Definition
greater than the pressure in the atmosphere
Term
What is 1 atm of pressure?
Definition
760 mm Hg
Term
If the volume of lungs increases, what happens to the air pressure inside the lungs?
Definition
decreases
Term
________ _________ is the amount of air that moves into the respiratory system during a single respiratory cycle.
Definition
Tidal volume
Term
Alveolar ventilation refers to the
Definition
movement of air into and out of the alveoli
Term
Henry's law states that
Definition
volume of gas that will dissolve in a solvent is proportional to the solubility of the gas and the gas pressure
Term
Partial pressure of oxygen in arterial blood is approximately?
Definition
100 mm Hg
Term
Partial pressure of carbon dioxide is greatest in
Definition
venous blood
Term
Chloride shift occurs in order to
Definition
transport bicarbonate ions into the blood plasma
Term
About 70% of carbon dioxide is transported in deoxygenated blood
Definition
as bicarbonate ions in the blood plasma
Term
Most of the oxygen transported by blood is
Definition
bound to hemoglobin
Term
What would increase the amount of oxygen discharged by hemoglobin to peripheral tissues?
Definition
decreased pH
Term
For maximum loading of hemoglobin with oxygen at the lungs the
Definition
PCO2 should be low
Term
Carbonic anhydrase
Definition
is in RBC
is an enzyme
can increase the amount of bicarbonate ion in plasma
can decrease the amount of bicarbonate ions in plasma
Term
Low pH alters hemoglobin structure so that oxygen binds less strongly to hemoglobin at low PCO2. This increases the effectiveness of
Definition
internal respiration
Term
The MOST important chemical regulator of respiration is
Definition
carbon dioxide
Term
Hypercapnia
Definition
elevated PCO2
Term
Apneustic centers of the pons
Definition
provide stimulation to the inspiratory center
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