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Physiology 2
Carl Christensen Physiology Exam 2
304
Biology
Undergraduate 3
09/30/2009

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Term
What are the 3 major processes involved in skeletal muscle contraction?
Definition

1. Excitation

2. Excitation / Contraction Coupling

3. Sliding Filament Mechanism

Term
The myofiber cell membrane is called the?
Definition
Sarcolemma
Term
What specifically opens the calcium gates in the axon terminal and synaptic end bulb?
Definition
When a nerve impulse (action potential) reaches the end of the axon
Term
What is the purpose of the moter end plate being highly folded?
Definition
Folds increase the surface area of the sarcolemma so that more Ach receptors can be located there
Term
What causes the difference in charges across the sarcolemma?
Definition
Selectively permeable membrane maintains higher extracellular concentration of sodium on the outside while some potassium and negative proteins are on the inside. Helped manitained by leaky Potassium channels and the sodium/potassium pump
Term
What causes the sarcolemma to depolarize?
Definition
Binding of Acetylcholine molecules to ion channel receptors (chemical gates) on the motor end plate opens ion channels this leads to permeability changes in Sarcolemma as sodium gates opena dn potassium gates close. As sodium enters the cell the membrane depolarizes.
Term
Depolarization of the sarcolemma results in the generation and propagation of what across the sarcolemma?
Definition
Action potential
Term
What triggers the release of calcium ions from the sarcoplasmic reticulum?
Definition
The action potential propagates along the sarcolemma and down the T tubules which triggers calcium release from the TERMINAL CISTERNAE of the voltage regulated sarcoplasmic retuculum
Term
What are the three thin filament proteins?
Definition
Actin, Tropomyosin and Troponin
Term
What is the thick myofilament?
Definition
Myosin
Term
What blocks the myosin heads from binding to the actin molecules?
Definition
Tropomyosin
Term
Which thin myofilament protein removes the myosin blocker?
Definition
Troponin
Term
How does Troponin remove the myosin blocker?
Definition
Troponin is made up of 3 proteins - one binds to actin, another binds to tropomyosin, and the 3rd binds to calcium ions. When calcium ions are present, troponin moves tropomyosin out of the way so that myosin can bind to actin.
Term
Describe the action of myosin heads as the sarcomere contracts.
Definition
Once tropomyosin is removed. myosin heads form "cross bridges" and attach and pull the thin actin toward the center of the sarcomere. and the muscle cell contracts. ATP powers this process
Term
What zones disappear when the sarcomere is fully contracted?
Definition
The H zone disappears and the I zone shortens.
Term

The sliding filament mechanism of muscle contraction states that which of the following contracts?

myofibrils, myofibers, myofilaments, sarcomeres, action and myosin

Definition
myofibrils, myofibers, and sarcomeres contract
Term

True or False?

According to the "all or none principle" if one sarcomere contracts then all of the sarcomeres in a myofiber (muscle cell) contract and the entire myofiber contracts?

Definition
True
Term

True or False?

According to the "all or none principle" if one myofiber contracts, then all of the myofibers in a muscle contract?

Definition
FALSE
Term

True or False?

You can have partial contraction of a myofiber?

Definition
FALSE
Term

True or False?

You can have partial contraction of a muscle?

Definition
TRUE
Term

True or False?

The proteins actin and myosin are components of contractile myofilaments

Definition
FALSE
Term

True or False?

The proteins actin adn myosin are components of myofilaments involved in muscle contraction

Definition
TRUE
Term
Explain the enzyme activity of the myosin head, what does it do to ATP?
Definition

When myosin binds to actin ADP and Pi are released from myosin heads resulting in a powerstroke. ATP is needed for the mysoin head to detach from the actin.

Myosin is an enzyme: It hydrolyzes ATP into ADP and Pi

Term
Describe myosin in its "high energy conformation"
Definition
The ADP / Pi complex remains bound to the myosin head
Term
Describe what happens during the "powerstroke" of the myosin head
Definition
ADP and Pi are released from the myosin head
Term
What must happen to myosin just before the powerstroke?
Definition
The myosin head with its ADP / Pi must bind to actin.
Term
What must happen in order for myosin to detach from actin?
Definition
A new ATP molecule has to bind to the mysoin heads, causing the head to detach from the actin
Term
Describe what happens in rigor mortis
Definition
Since ATP is required to detach the actin from the myosin, they become permanently bound in the absence of ATP and the muscles become rigid.
Term
What must happen to ACh in order for muscl erelaxation to occur?
Definition
Acetylcholinesterase must break down Ach in the Synaptic Cleft
Term
What must happen to calcium in order for muscle relaxation ot occur?
Definition
When action potential is  no longer present, Calcium is pumped back into the Sarcoplasmic Reticulum.
Term
What must happen to actin/troponin/tropomyosin in order for muscle relaxation to occur?
Definition
ATP must bind to myosin and myosin detaches from action - thus crossbridges are broken
Term

The 'all or none' principle applies to which of the following?

sarcomere, muscle cell, myofiber, muscle, myofibril, or motor unit?

Definition
sarcomere, muscle cell, myofiber, myofibril, and motor unit.
Term
How is it possible to have partial contraction of a muscle?
Definition
If one motor unit in a muscle contracts, that does NOT mean that all of the motor units contracted. Within a muscle, a few, many, or all of its motor units can contract at any given time.
Term
List the 3 metabolic processes that provide ATP for muscle cell contraction.
Definition

1. Phosphagen System

2. Anaerobic Glycolysis and Lactic Acid System

3. Aerobic Respiration.

Term
Write the chemical reaction for phosphagen system:
Definition
Creatine phosphate + ADP ----> Create + ATP
Term
Stored ATP and the phosphagen system supply enough energy for how many seconds?
Definition
15 seconds
Term
The muscle cell does not store large amounts of ATP, but stores greater amounts of what?
Definition
Creatine Phosphate
Term
During Strenous exercise, when adequate oxygen is not available, pyruvic acid is converted to what?
Definition
lactic acid
Term

The process of convertying pyruvic acid to lactic acid is aerobic or anaerobic?

You should know that this can lead to muscle fatigue

Definition
anaerobic
Term
Why does the conversion of lactic acid and pyruvic acid lead to muscle fatigue?
Definition
Process does not produce enough ATP and the drop in pH inhibits enzyme activity
Term
Describe "oxygen debt" and explain why it must be repaid.
Definition
Lactic acid accumulates and oxygen is needed to convert lactic acid into carbon dioxide and water to replenish energy stores.
Term
Where does aerobic respiration occur in the cell? Why is this process considered aerobic?
Definition
aerobic respiration occurs in mitochondria. This requirse oxygen and involves glycolysis, the kreb's cycle,a dn the electron transport chain.
Term
Most of the ATP used for muscle activity comes from which metabolic process?
Definition
aerobic respiration
Term
Explain the difference between physiological and psychological muscle fatigue
Definition
physiologic muscle fatigue results when the muscle physically canno tcontract since the cell is consuminjg ATP faster than it can produce it. Psychologic fatigue occurs when one feels very very tired.
Term
Exercise can increase muscle size. Name the factors that are involved in the increased muscle size
Definition

Increase in the # of mitochondria

Increase in the size of muscle fibers

increase in amount of connective tissue around the muscle.

Term
An athlete with a larger number of slow oxidative myofibers would be a good what?
Definition
marathon runner
Term
Differentiate between oxidative and glycolytic myofibers
Definition
Oxidative fibers are red fibers, fatigue resistant and generate ATP aerobically. Glycolytic fibers are always fast twitch, fatigable white fibers that contain a large amount of glycogen and generate ATP anaerobically.
Term
Differentiate between fast twitch and slow twitch myofibers
Definition
Both are aerobic fatigue resistant red fibers, however, slow twitch aids postural muscles and fast twitch helps explosive aerobic activity like sprintign
Term
Differentate between red and white myofibers.
Definition
Red fibers contain large amounts of myoglobin whcih bnid to oxygen and white twitch contains less myoglobin but is better adapted to geneate ATP anaerobically.
Term
What is occurring at the cellular level durnig the latent period?
Definition
Interval from stimulus until muscle starts to shorten, no observable activity, but electrical and chemical changes are occuring.
Term
Wha tis referred to as the staircase effect? What happens to force production with each subsequent stimulus? Why does this occur?
Definition
Stair case effect. The force for the 1st contraction is less in subsequent contraction within a relatively narrow time span. Each successive stimulation produces slightly mroe force than the previous contraction. Caused by an inrease efficiency enzyme system within the cell and increased intracellular calcium availability.
Term
Name 2 ways to increase the amount of force produced by muscles
Definition
Multiple Motor Unit summation and Wave summation
Term
Differentiate between threshold stimulus and maximal stimulus
Definition
Threshold is the voltage at which the first perceptible contactile response is obtained. Maximal stimulus the weakest stimulus at which all of the msucle cells are contracting, past this point increased stimulus intensity does not lead to a stronger contraction.
Term
Increasing muscle force b y increasing stimulus frequency is called what?
Definition
WAve summation
Term
Why does wave summation occur?
Definition
Occurs w hen a muscle is already in a partially contracted state when the stimulus is delivered
Term

True or False

With wave summation the muscle is allowed to fully relax.

Definition
FALSE
Term
What is an extreme form of wave summation that results in a steady, sustained contraction?
Definition
Tetanus
Term
Name the three coverings of the spinal cord and brain from superficial to deep
Definition
dura mater, arachnoid mater, pia mater
Term
How many pairs of spinal nerves are there?
Definition
31
Term
Each spinal nerve is connected to the spinal cord at 2 points called?
Definition
Posterior (dorsal) root and anterior (ventral) root
Term
What causes the swelling in the posterior root (called the posterior root ganglion)
Definition
Somas of unipolar afferent neurons
Term
Which root is the sensory (afferent) root and which root is the motor (efferent) root?
Definition

Posterior (dorsal) = sensory (afferent)

anterior (ventral) = motor (efferent)

Term
Which root is the sensory (Afferent) root?
Definition
posterior or dorsal root.
Term
Which root is the motor or efferent root?
Definition
anterior or ventral root
Term
for reflexes, what does R.I.P. mean?
Definition
rapid, involuntary, and predictable
Term
Many reflexes are controlled by what part of the CNS?
Definition
Spinal cord
Term
Where does a reflex begin?
Definition
sensory receptor
Term
Where does a reflex end?
Definition
effector organ
Term
Define neuromuscular junction:
Definition
synapse between a neuron and a muscle cell.
Term
Name the three types of neurons involved in a reflex arc
Definition

1. sensory or afferent (Unipolar)

2. Interneuron (multipolar)

3. Motor or efferent (Multipolar)

Term
Name the 5 components of a relfex arc.
Definition

Sensory receptor

Afferent neuron

Integration center (may contain an interneuron) efferent neuron

effector

Term
Reflex arcs can be classified as somatic or autonomic by looking at what?
Definition
effector
Term
Name the effector of a somatic reflex
Definition
skeletal muscle
Term
Name the effectors of an autonomic reflex
Definition
Smooth muscle, cardiac muscle, and glands
Term
A receptor potential is the same as what?
Definition
graded potential
Term
If threshold is reached on the axon, what type of potential is generated?
Definition
Action potential.
Term
Give an example of a stretch reflex?
Definition
patellar or knee jerk reflex
Term
What stimulus initates the patellar reflex?
Definition
Stretching the muscle specifically the muscle spindle in the muscle
Term
Tapping the patellar ligament has what effect on the quadriceps muscle?
Definition
lengthens the quadricep muscle
Term
What receptor is stimulated in the muscle when you tap the patellar ligament?
Definition
Muscle spindle
Term
What muscles contract as a result? Does the lower leg flex or extend as a result?
Definition
Quadricep muscle contracts: the lower leg extends as a result.
Term
What muscles are inhibited during the patellar reflex?
Definition
Hamstrings (antagonistic group to quads)
Term
What stimulus initiates the deep tendon reflex?
Definition
Contraction of the quadricep muscle, increasing tension in quadricep tendon
Term
What receptor is stimulated in the deep tendon reflex?
Definition
Golgi tendon organ
Term
What muscle contracts as a result in the deep tendon refelx?
Definition
hamstrings
Term
what muscles are inhibited in the deep tendon reflex?
Definition
quadriceps
Term
Give an example of a flexor reflex
Definition
when you touch something hot and you withdraw (flex) your arm
Term
Is thsi reflex contralateral or ipsilateral?
Definition
Ipsilateral (same side)
Term
Give an example of a crossed extensor reflex
Definition
Someone startles you by grabbing your arm; you withdraw the arm they grab (flexion) and put the other hand up to defend yourself (extension)
Term
Is the crossed extensor reflex contralateral or ipsilateral?
Definition
Both; the flexion is ipsilateral, the extension is contralateral.
Term
Describe the basic function of a sensory receptor.
Definition
They respond to changes in the environment, called stimuli, activation results in graded potentials (depolarization) that can trigger an action potential in the afferent neuron
Term
What kind of potential occurs in a sensory receptor.
Definition
graded
Term
Where does sensation awareness and interpretation actually occur?
Definition
CNS
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

Located near surface of body?

Definition
Exteroreceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

located in muscles, tendons, ligaments and joints

Definition
Proprioceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

Located in blood vessels and viscera

Definition
enteroreceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

taste buds

Definition
exteroreceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

root hair plexuses

Definition
exteroreceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

provide information about internal environment?

Definition
enteroreceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

touch receptors

Definition
exteroreceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

receptors for equilibrium

Definition
Proprioceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

Provide information about body position and movement

Definition
proprioceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

retina

Definition
exteroreceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

Provide information about external environment

Definition
Exteroreceptor
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

pressure receptors

Definition
exteroreceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

organ of corti

Definition
exteroreceptors
Term
temperature receptors of skin
Definition
exteroreceptors
Term

Exteroreceptor Enteroreceptor or Proprioceptor?

olfactory epithelium

Definition
exteroreceptor
Term
As far as mechanoreceptors, thermoreceptors, nociceptor, photoreceptor or chemoreceptor, whats the rule of thumb?
Definition
Unless its totally obvious, its a mechanoreceptor.
Term
List the 4 conditions that must be satisfied in order for a sensation to occur
Definition

1. a stimulus (change in the environment) is present

2. A receptor or sense organ detects the stimulus and coverts it to a nerve impulse

3. conduction of impulse occurs along a neural pathway from the receptor to the brain

4. Translation of the nerve impulse into a sensation by a region of the brain; until the CNS translates the impulse, its not a sensation

Term
List / Describe the 4 major characteristics of all sensations
Definition

1. projection - process by which the brain refers sensations to their point of stimulation

2. Adaptation - a decrease in sensitivity to continued stimuli

3. afterimages - sensation that persists even though the stimulation has bene removed.

4. modality - characteristic of reach sensation that allows it to be distinguished from other types

Term
Give an example of the adaptive characteristic of senses
Definition
smell - you smell your own perfume when you first put it on and then dont smell it after a short time
Term
Give an example of the projection characteristic of senses
Definition
You can tell where a sound is coming from; you can tell what part of th body is being touched
Term
Describe the olfactory receptor cell
Definition
Olfactory receptor cells in the olfactory epithelium are really bipolar neurons whose distal ends contain a dendrite that terminates in olfactory hairs (6 - 8 that react to odors and stimulate the olfactory receptor cells); at proximal ends of these neurons are axons that pass through holes in the cribriform plate of the ethmoid bone and synapse with neurons in the olfactory bulbs
Term
In order to activate olfactory receptors, a chemical must be what?
Definition
volatile and water soluble
Term
Olfactory receptor cells synapse with what neurons in the olfactory bulbs?
Definition
mitral
Term
Smell transuction occurs through what mechanism?
Definition
G protein
Term
The G protein mechanism is a second messenger system. What molecule acts as the second messenger?
Definition

Cyclic amp

 

Term
The first step in smell transduction, an odorant chemical binds to what?
Definition
a G protein receptor
Term
the second step in smell transduction the G protein activates the enzyme????
Definition
adenylate cyclase
Term
Once Cyclic amp is formed from ATP cyclic amp opens up what channels?
Definition
Na channels which influx and results in depolarization
Term
Adaptation to smell occurs from olfactory bulbs which contain what kind of cells and release what neurotransmitter
Definition
olfactory bulbs contain granule cells that release GABA
Term
Is GABA excitatory or inhibitory on mitral cells?
Definition
both
Term
Olfactory tracts carry impulses to two main destinations, what are they?
Definition
Thalamus to olfactory cortex (temporal and frontal lobes) and limbic system
Term
Four steps for the activation of taste buds
Definition

1. chemical must dissolve in saliva

2. Once dissolved, substances can then enter the taste pores and bind to protein receptors on the gustatory hairs

3. Binding on gustatory hairs results in depolarization and releases neurotransmitters from synaptic vesicles

4. Binding of neurotransmitters to sensory dendrites triggers a graded potential that then can elicit an action potential in these neurons

 

Term
How is taste transducted?
Definition
Only partly known; sweet responses are mediated by a G protein mechanisms causes closer of K+ channels
Term
Gustatory pathway
Definition

Afferent nerves found in facial (VII) glossopharngeal (VIII) and in the vagus (X)

these tracts carry impulses to thalamus and then to gustatory cortex in parietal lobes and also to the limbic systen so we can appreciate what we eat.

Term
What are the sensory receptor organs for taste?
Definition
Taste buds
Term
Describe the gustatory receptor cell?
Definition
taste buds contain the gustatory receptor cells; each receptor cell contains a gustatory hair (a long microvillus) that projects to the external surface through  a taste pore; coiling around the receptor cells are sensory dendrites that transmit impulses to the brain
Term
Where are taste buds found?
Definition
they are located in papillae (the bumps) of the tounge, soft palate and throat
Term
What are the primary taste sensations?
Definition
sour, salt, bitter, sweet, savory or umami, and now maybe fat; other tastes are combinations of these four that are modified by smell.
Term
Besides taste receptors, what other receptors are found in the both
Definition
thermoreceptors, mechanorecepotrs and nociceptors
Term
for a chemical to be tasted, it must dissolve in....?
Definition
saliva
Term
What part of the internal ear functions in audition?
Definition
ochlea
Term
Name the 3 canals of the cochlea
Definition

Scala vestibule which is bony so if its bony it has periliymph

scala Media which is Membranous so if it is membranous it has endolymph

Scala tympani which is bony so if it is bony it has perilymph

Term
What part of the cochlea is directly responsible for detecting sound waves and generating a nerve impulse?
Definition
Organ of corti - rests on basilar membrane; consists of hair cells; hair cells are in contact with dendrites of the cochlear branch of the vestibulocochlear (VIII) nerve
Term
What nerve is associated with audition and equilibrium?
Definition
Vestibulocochlear VIII
Term
Sound travels as...?
Definition
sine waves
Term
Frequency is the same as....?
Definition
pitch
Term
Pitch or frequency corresponds to what of the sine wave?
Definition
wavelength
Term
Where do high frequency sound waves trike the vestibular membrane in the cochlea?
Definition
Near the base of the cochlea, close to the oval window; this part of the vestibular membrane is stiffer so only high energy waves can make it vibrate
Term
Where do low frequency waves strike the vestibular membrane?
Definition
Near the apex of the cochlea; this part of the vestibular membrane is more flexible so low energy waves can make it vibrate
Term
Intensity is the same as??
Definition
Loudness
Term
Loudness or intensity corresponds to...?
Definition
amplitude (height) of the sine wave.
Term
How does the brain detect differences in intensity?
Definition
# of AP generated
Term
What structure is responsible for absorbing excess waves entering the scala tympani?
Definition
Round window
Term
Auditory transduction
Definition
  • Pressure waves in the endolymph of the scala media cause the basilar membrane to vibrate. When the membrane vibrates the hairs of the hair cells bend. Bending them in one direction causes depolarization of the receptor cell; bending them in the other direction causes hyperpolarization of the receptor cells. deplarization causes increase  in the release of neurotransmitters from the receptor, hyperpolarization causes a decrease in the release of neurotransmitters from the receptor. Therefore, depolarizzation causes excites associated dentrites. Therefore, hyperpolarization inhibits associated dendrites
Term
Name the 2 general parts of the internal ear that function in equilibrium?
Definition
vestibule and semicircular canals
Term
The vestibule functions in what kind of equilibrium?
Definition
static
Term
The semicircular canals function in what kind of equilibrum?
Definition
dynamic
Term
What kind of equilibrium monitors the position of the head in space and responds to linear acceleration?
Definition
Static
Term
What kind of equilibrium responds to rotational movements?
Definition
Dynamic
Term
The membranous labyrinth savs within the vestibule are the?
Definition
utricle and the saccule
Term
The sensory receptors for static equilibrium are the?
Definition
Maculae
Term
What kind of receptor is the maculae?
Definition
Mechanoreceptors
Term
Describe the maculae?
Definition

A macula is a flat epithelial patch containin gsupporting cells and hair cells; hair cells ahve numerous stereocilia long microvilli and a single kinocilium, a true cilium, extending from their surfaces. These "hairs" are embedded in jellylik emass called an otolithic membrane; this membrane contains calcium carbonate crystals called otoliths "ear stones"

Sensory neuron dendrites of the vestibular nerve void around the bases of the hair cells.

Term
When the head is upright the utricle macula hairs are?
Definition
vertical and respond best to horizontal movements.
Term
When the head is upright the saccule macula hairs are?
Definition
horizontal and respond best to verticle movements
Term
The membranous labyrinth sacs within the semicircular canals are the?
Definition
semicircular ducts
Term
The sensory receptor for dynamic equilibrium is the ?
Definition
crista ampularis
Term
How many dynamic equilibrium crista ampularis receptors are there?
Definition
3
Term
Describe the crista ampularis?
Definition

Each crista is a tiny elevation in the ampulla of each semicircular canal. It is composed of supporting cells and hair cells.

Each hair cell has a sterocilia and one kinocilium tha tproject into the cupula (a gel like substance that looks like a pointed cap) sensory neuron dendrites of the vestibular nerve coil around the base of hair cells.

Term
Cristae respond to changes in the velocity of what kind of movement? Note, not the movement itself
Definition
rotatory movements
Term
Cristae hair cells function the same way as what kind of hair cells?
Definition
Organ of corti hair cells.
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

specialized for color vision and shrpness of vision

Definition
Cones
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

specialized for vision in dim light and perpheral vision

Definition
Rods
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

Their axons form the optic nerve

Definition
Ganglion neurons
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

photoreceptor cells that participate in converging pathways (as many as 100 feed into each ganglion nueron_

Definition
Rods
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

photoreceptor cell that has its own straight-through pathway (has its own bipolar neuron and ganglion neuron)

Definition
Cones
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

Form the middle layer of the retina; link rods and cones to ganglion nuerons

Definition
Bipolar neurons
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

Generates the action potentials that go to the braIN?

Definition
gangLION neurons
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

Many more of this type of photoreceptor cell than the other?

Definition
Rods
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

More of this photoreceptor in fovea centralis?

Definition
Cones
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

More of this type of photorecptors in the peripher of the retina?

Definition
Rods
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

contains phtopigment iodopsin?

Definition
Cones
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

produces three types of photopigments?

Definition
Cones
Term

Rods, Cones, Bipolar neurons, or ganglion neurons

Glutamate is inhibitory on this cell?

Definition
Bipolar neurons
Term
Why is the optic disc called the blind spot?
Definition
When light is focused on this spot, no image is formed; there are no rods or cones at this spot on the retina; this is where ganglion neuron axons exit the eye to form the optic nerve
Term
What is the oval region found lateral to the optic disc?
Definition
Macula lutea
Term
The center of the macula lutea is called the ?
Definition
fovea centralis
Term
The fovea centralis contains only?
Definition
cones
Term
Anything we wish to view crtiically is focused on the?
Definition
fovea centralis
Term
all radiations travel is..?
Definition
waves and have characteristic wavelenghts
Term
What part of the electromagnetic spectrum can we see?
Definition
visible light
Term
Light passing through a convex lens does what?
Definition
Converges
Term
Light passing through a concave lengs does what?
Definition
diverges
Term
As light enters the eye it is refracted 3 major times, when does this occur?
Definition

cornea

entering the lens

Leaving the lens

Term
When rhodopsin is in the dark configuration, Na channels in the rods are?
Definition
Open
Term
If na channels in the rods are open then what will the rods do?
Definition
release the nuerotransmitter glutamate
Term
In the presence of glutamate, bipolar neurons are excited or inhibited?
Definition
Inhibited
Term
If the bipolar neuron is inhibited by glutamate then the biplar cell does what?
Definition
hyperpolarizes
Term
If the bipolar neuron is inhibited by the presence of glutmate and hyperpolarizes than is an impulse send to the brain via the gnglion neurons?
Definition
No, it is not
Term
During the light configuration of rhodopsin, Na channels in the rods are ?
Definition
closed
Term
If Na channels in the rods are closed than rods do what?
Definition
they do not release glutamate
Term
If the Na channels are closed and rods do not release glutamate than in the ABSENCE of glutamte bipolar neurons are what?
Definition
Excited
Term
If there is an absence of glutamate and biplar nuerons are excited than they do what?
Definition
Depolarize and if they depolarizae than an impulse  IS sent to the brain via the ganglion nuerons during a LIGHT configuration of rhodopsin
Term
What are the 3 types of cones?
Definition
Red, blue, green
Term
After light goes through the retina and the optic nerve, it will then go through the?
Definition
optic chiasm
Term
After the optic chiasm, light goes through the optic tract and then onto the
Definition
superior colliculi in corpora quadrigemina
Term
After light goes through the superior colliculi in the corpora quadrigemina it will pass to the ?
Definition
thalamas which relays it to the visual cortex in the occipital lobe.
Term
The lateral visual fields projects onto the what retina?
Definition
medial retina
Term
Medial visual fields project onto the what retina?
Definition
lateral retina
Term
Lateral visual fields are interpretted by the same side or opposite side of the brain?
Definition
opposite side
Term
medial visual fields is interpretted by the opposite or same side of the brain?
Definition
same side
Term
What allows for binocular vision?
Definition
Visual fields partially overlap
Term
How do we judge the distance of an object?
Definition
Because we see an object with both eyes, the image of the object reaches the reinta of one eye at  slightly different angle from that of the other. The brain can interpret these difference in angle so that distance can be judged accurately.
Term
What is theonly cranial nerve that does not innervate head and neck structures?
Definition
Vagus
Term
What neuroglial cells help form BBB in regular blood capillaries?
Definition
Astrocytes
Term
What neuroglail cells help form the BBB in choroid plexus capillaries?
Definition
Ependymal cells
Term

Right hemisphere or left hemisphere?

spoken and written langauge?

Definition
Left hemisphere
Term

Right hemisphere or left hemisphere?

musical and artistic awareness?

Definition
Right hemisphere
Term

Right hemisphere or left hemisphere?

numerical and scientific skills?

Definition
left hemisphere
Term

Right hemisphere or left hemisphere?

imagination

Definition
right
Term

Right hemisphere or left hemisphere?

generating mental images of sight, touch, taste, and smell?

Definition
right
Term
The input neurons of the cortex are called?
Definition
stellate cells
Term
The output neurons of the cortex are called?
Definition
pyramidal cells
Term
What are the 4 major areas of the motor cortex?
Definition
premotor, primary motor, broca's area, frontal eye field
Term
Where is the primary motor cortex located?
Definition
precentral gyrus
Term
The primary cortex contains what cells that have long axos that project to the spinal cord?
Definition
pyramid cells
Term
What other 2 major brain structures are also involved in motor contral and receive input from the cortex?
Definition
basal nuclei, cerebellum
Term
What is the function of Broca's area?
Definition
special motor speech area tha tdirects muscles of tongue, throat, and lips involved in speech production (motor program for speech)
Term
Broca's area recieves input from?
Definition
Wernicke's area (formulates phrase)
Term
The area in the right hemisphere tha tmirrors Broca's area controls?
Definition
emotional aspect of speech
Term
Where is the primary sensory area of the cortex?
Definition
Postcentral gyrus
Term
Where is the Visual sensory area found?
Definition
occipital region
Term
Where is the auditory sensory area found?
Definition
Temporal and insula
Term
Where is the olfactory sensory area found?
Definition
Frontal and temporal
Term
Where the gustatory sensory area found?
Definition
Parietal and insula
Term
What does Wernickes area control?
Definition
Formulates phrases according to learned rules of grammar and transmits them to Broca's area
Term
The area that mirrors Wernicke's area in the right hemisphere recognizes?
Definition
emotional aspects of speech; think about what would happen if this area was nonfunctional. How would you know if someone was joking or not?
Term
What areafigures out what you are going to say?
Definition
Wernicke's area
Term
What area in speech tells your tongue, vocal cords, etc. how to say it?
Definition
Broca's area
Term
Commissural fibers
Definition
connect corresponding gray areas of two hemispheres. fibers run horizontally
Term
association fibers
Definition
connect different regions of same hemisphere; the fibers run horizontally, but in the same hemisphere
Term
Projection fibers
Definition
include fibers entering brain from lower brain or cord centers, and fibers leaving cortex to travel to lower areas; fibers run vertically
Term
Cerebral whit ematter is composed of axons from
Definition
pyramidal neurons
Term
Name the 3 basal nuclei
Definition
Putamen, globus pallidus, caudate nucleus
Term
The basal nuclie receive input from what? What is the general function?
Definition
Basal nuclei receive input from cerebral cortex. the general function is output to premotor and prefrontal cortices to influence muscle movements; help to plan and program voluntary movements (motor control) especially highly practiced behaviors that you carry out without much thought (driving a car); input is necessary to our abaility to perform several activities at once
Term
Name 6 centers of the medulla oblongata
Definition
cardiac, vasomotor, respiratory, vomiting, hiccupping, sneezing, gagging, swallowing. etc.
Term
What are 3 major structures of the midbrain?
Definition

1. substantia nigra

2. Cerebral peduncles

3. Corpora quadrigemina (superior and inferior collicili)

Term
Name the 6 major structures of the limbic system
Definition

1. Thalamus,

2. hypothalamus

3. olfactory bulbs

4. fornix

5. mamillary bodies

6. temporal lobe (amygdale and hippocampus)

Term
Why are the mammillary bodies and fornix part of limbic system?
Definition
They are involved in smell and the emtoional connections you ahve to smells.
Term
How does reticular formation effect somatic motor control?
Definition
Connects cortex to spinal cord tracts taht adjust mucle contraction to maintain tone, balance, and posture
Term
How does reticular formation effect cardiovascular control?
Definition
Includes cardiac center and vasomotor center of medulla oblongata
Term
How does reticular formation effect sleep and consciousness?
Definition
Injury to reticular formation can result in coma; also this is the target of general anesthetics
Term
How does reticular formation effect sensory filter?
Definition
Acts like a filter for the flood of sensory inputs that our bodies receive - repetitive, familiar, or weak signals are filters out, but unusual, significant, or strong impulses do reach our consciousness
Term
How are the 4 brain waves differentiated?
Definition
By amplitude (wave height) and frequency
Term
What is the frequency of delta waves?
Definition
3.5 Hz
Term
What is the frequency of Beta waves?
Definition
14 to 30 Hz
Term
What wave is in normal in infants and adults in deep sleep; indicates serious brain damage in awake adults?
Definition
delta waves
Term
What brain wave is normal in childrena dn sleeping adults; suggestion emotional stress or brain disorders in awake adults?
Definition
theta
Term
What brain waves exist  when the person is awake, resting, and eyes closed, mind wandering?
Definition
alpha
Term
What wave is seen during mental activity and sensory stimulation; recorded in frontal to parietal region?
Definition
Beta waves
Term
What 2 brain structures co ntrol circadian rhythm?
Definition
Reticular formation and hypothalamus
Term
Describe the changes in EEG as a person moves from drosy to deep sleep?
Definition
EEG waves increase in amplitude and decrease in frequency
Term
What brain waves is associated with lowest vital sign rates?
Definition
Delta
Term
What temporal lobe structure is responsible for storing short term memories?
Definition
hippocampus;
Term
How does the hippocampus turn a short term memory into a long term memory?
Definition
it plays memories back to cortex over and over again
Term
How is the amygdala involved in memory storage?
Definition
Has connection to diencephalon (thalamus and hypothalamus - part of limbic system tha tmay enable sensory events to develop emotional assocations; may also limit attention and learning to stimuli with emotional significance
Term
What brain structure plays an important role in learning motor skills?
Definition
cerebellum
Term

Somatic Nervous System or Autonomic Nervous System?

2 motor neurons?

Definition
Autonomic
Term

Somatic Nervous System or Autonomic Nervous System?

heavily myelinated fibers?

Definition
Somatic Nervous System
Term

Somatic Nervous System or Autonomic Nervous System?

Lightly myelinated fibers?

Definition
Autonomic Nervous System
Term

Somatic Nervous System or Autonomic Nervous System?

Thick Axons?

Definition
Somatic Nervous system
Term

Somatic Nervous System or Autonomic Nervous System?

Fast conduction?

Definition
Somatic Nervous System
Term

Somatic Nervous System or Autonomic Nervous System?

Slow conduction?

Definition
Autonomic Nervous System
Term

Thin  Axons?

Somatic Nervous System or Autonomic Nervous System?

Definition
Autonomic Nervous System
Term

Sympathetic Or Parasympathetic?

Short pre- long post?

Definition
Sympathetic
Term

Sympathetic Or Parasympathetic?

Pre releases ACh

Definition
Both
Term

Sympathetic Or Parasympathetic?

Post releases ACh?

Definition
Parasympathetic and Sympathetic in blood vessels, sweat glands, and errector pili muscles
Term

Sympathetic Or Parasympathetic?

more complex?

Definition
Sympathetic
Term

Sympathetic Or Parasympathetic?

innervates more organs?

Definition
Sympathetic
Term

Sympathetic Or Parasympathetic?

"Craniosacral'?

Definition
Parasympathetic
Term

Sympathetic Or Parasympathetic?

Thoracolumbar?

Definition
Sympathetic division
Term
Why is the adrenal medulla sometimes called a "misplaced ganglion?
Definition

It arises from the same embryologic tissue as a post sympathetic ganglion; it produced epinephrine, which is similar to NE.

 

 

Term
Nicotinic Receptors?
Definition

cholinergic receptors that also bind to nicotine; ACh binding nicotine receptors is always excitatory

found on adrenal medulla cells

Term
Muscarinic Receptors?
Definition

cholinergic receptors can be excitatory or inhibitatory depending on target organ. On heart slows it down on g.i. tract increases activity.

all parasympathetic target organs.

few sympathetic targets like sweat glands, blood vesssels.

Term

Nicotinic, Muscarinic, Or Adrenergic?

Binds to ACh?

Definition
Nicotinic and Muscarinic
Term

Nicotinic, Muscarinic, Or Adrenergic?

Binds to NE

Definition
adrenergic
Term

Nicotinic, Muscarinic, Or Adrenergic?

ALWAYS excitatory?

Definition
Nicotinic
Term

Nicotinic, Muscarinic, Or Adrenergic?

excitatory or inhibitory?

Definition
Muscarinic and Adrenergic
Term

Nicotinic, Muscarinic, Or Adrenergic?

on motor end plate of skeletal muscles?

Definition
Nicotinic
Term

Nicotinic, Muscarinic, Or Adrenergic?

On post ganglionic neurons in both divisions?

Definition
Nicotinic
Term

Nicotinic, Muscarinic, Or Adrenergic?

On adrenal medulla?

Definition
Nicotinic
Term
On parasympathetic target organs?
Definition
Muscarinic
Term
On sympathetic target organs?
Definition
Mostly Adrenergic.....a few muscarinic. blood vessels, sweat glands and arector pili muscles
Term

Nicotinic, Muscarinic, Or Adrenergic?

Include alpha and beta receptors?

Definition
Adrenergic
Term
What does SLUDD stand for? for PSD
Definition
Salivation, lacrimation, urination, digestion, and defecation.
Term
What are the 4 Es for SD?
Definition
embarassment, excitement, excercise, and emergency
Term

Parasmpathetic or sympathetic?

pupil dilation?

Definition
sympathetic
Term

Parasmpathetic or sympathetic?

regulates body temp?

Definition
sympathetic division
Term

Parasmpathetic or sympathetic?

stimulates gallbladder?

Definition
PSD
Term
Explain sympathetic tone as it relates to blood vessels?
Definition

Sympathetic (Vasomotor) Tone - The SD is the major controller of blood pressure, even at rest. The vascular system is almost entirely innervated by sympathetic fibers that keep the blood vessels in a continual state of partial constriction called sympathetic tone. When faster blood delivery is needed, these fibers deliver impulses more rapidly, causing blood vessels to constrict and blood pressure to rise. When blood pressure is to be decreased, the vessels are allowed to dilate.

 

Term
Why is sympathetic longer lived than parasympathetic?
Definition

1. complexity of synapses - SD is more complex and innervates more organs

2. Neurotransmission elimination - ACh is broken down in cleft by acetylcholinesterase, NE takes longer as it has to be pumped back into presynaptic membrane.

3. Effects of adrenal medulla = secretes epi

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