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Physiological Changes during Pregnancy
Lecture 2
69
Nursing
Undergraduate 3
04/09/2016

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Term
What happens to the uterus physically during pregnancy?
Definition
1. Increased vascularity/dilation of blood vessels
2. hyperplasia-new muscle fibers/tissue
3. hypertrophy-enlargement of pre-existing fibers
4. development of the decidua
5. growth changes R/T stimulation from high levels
of estrogen/progesterone
5. shape changes
6. position changes
Term
What is the dicidua?
Definition
the thick layer of modified mucous membrane (ednometrial lining) that lines the uterus during pregnancy and is shed with the afterbirth
Term
What are the positions of the uterus at different time periods?
Definition
-12 weeks-at or above the symphysis pubis
-16 weeks-between SP and umbilicus
-20 weeks-at the umbilicus
-36 weeks-almost to the xiphoid process
Term
At which week should the distance the fondus to the symphysis pubis equal gestational age?
Definition
16 weeks
Term
What happens when lightening occurs?
Definition
The baby drops
-nulliparas-2 weeks before term
-multiparas-when labor starts
Term
What is ballottement?
Definition
The fetus is not yet in the pelvis but can be palpated floating structure
Term
Why do pregnant mother's waddle?
Definition
They have an altered center of gravity as enlarging uterus tilts
against the anterior abdominal wall
Term
What are the Bracksten-Hicks contractions?
Definition
They are irregular, painless contractions that help to facilitate blood flow and start around 4 months. Too many could be preterm labor.
Term
What is important to know about uteroplacental blood flow?
Definition
1. uterine blood flow increases
2. more oxygen is extracted from the blood in the latter part of the pregnancy
3. At the end of pregnancy, 1/6 of total blood volume within the vascular system of uterus
4. Anything that can effect blood supply can cause bad effects to the fetus:

Ex: supine hypotension, rupture of the uterus or placenta, smoking
Term
What is Hegar’s sign?
Definition
6 weeks-softening of lower uterine segment (very uncomfortable)
Term
What are changes in the uterus?
Definition
1. Goodell’s sign-softening of cx-6 weeks
2. Chadwick’s sign-bluish cast-8 weeks
3. friability increases
4. operculum-mucus plug-endocervical glands (snot, may take a while to come out may last all pregnancy)
Term
What could also create Chadwick's sign?
Definition
Abuse
Term
What happens during pregnancy to the vagina?
Definition
1. increased vascularity
2. leukorrhea-thick white vaginal discharge
3. change in pH leads to higher risk for yeast inf.
Term
What happens to the breasts during pregnancy?
Definition
1. start to change by week 6 R/T hormone surge
2. increase in sensitivity, breast and nipple size
3. increase in feeling firm, heaviness, nipple erect
4. nipples and areola become more pigmented
5. vessels beneath the skin dilate-more visible
6. striae gravidarum (stretch marks) may appear
7. may leak colostrum as early as 16 weeks
Term
What can happen to breast stimulation during pregnancy?
Definition
Breast stimulation can stimulate production of oxytocin causing contractions. This could lead to preterm labor.
Term
What happens to the heart during pregnancy?
Definition
1. slight hypertrophy R/T increase blood flow
2. position change R/T diaphragm position
3. transient murmurs may be auscultated
4. cardiac output
-increased 30-50% by week 32
-only 20% increase by week 40
-R/T increased stroke volume and heart rate
6. pulse rate increases 10-15 bt/min
Term
Why will cardiac issues present in a pregnant mother?
Definition
The blood volume increases by 50% and puts more stress on the heart.
Term
What happens to the blood during pregnancy?
Definition
1. increase in blood volume 40-50% (1500ml)
-plasma-1000 ml
-RBC’s-450 ml
2. physiological anemia-hemodilution of cells
-anemic if Hgb under 10g/dl, Hct under 35%
3. increase in WBC’s
4. coag times
-circulation time decreases by week 32 near normal at term
-↑ in clotting factors leads to ↑ tendency for blood to coagulate
-↑ risk for thrombosis-esp. with C/S
Term
What happens to blood pressure during pregnancy?
Definition
1. 1st trimester-no change in BP
2. 2nd trimester-BP ↓ 5-10 mm Hg
3. 3rd trimester-BP returns to 1st trimester values
4. supine hypotensive syndrome
-if they lie on their backs
-at 5 minutes, reflex bradycardia (fetus HR)
-CO ↓ by half
-woman feels faint
Term
What drink should you use when taking Fe supplement?
Definition
Orange juice increases absorption
Term
What can a nurse suggest to promote circulation in a pregnant woman?
Definition
Walk around, put feet up when sitting, wear compression stockings
Term
What should a nurse tell someone who is taking Fe supplement?
Definition
Stool will look tarry color, you may be constipated, drink plenty of water
Term
What happens to the rib cage during pregnancy?
Definition
It flares out
Term
How does breathing shift during pregnancy?
Definition
From Abdominal to thoracic
Term
Why is there elevated maternal oxygen requirements during pregnancy?
Definition
1. acceleration in metabolic rate
2. the need to add to the tissue mass of uterus
3. fetal needs
Term
What happens when ↑ vascularity of the upper resp. tract during pregnancy?
Definition
1. nasal and sinus stuffiness-(estrogen-induced)
2. epistaxis (nosebleeds) & gum bleeds are normal
3. changes in the voice
Term
What does relaxin do?
Definition
It softens cartilage throughout the body: used for rib cage expansion, and pelvis but also affects joints (may cause knee pain)
Term
What happens to the pulmonary function during pregnancy?
Definition
1. deep breathing-↓ airway resistance-Progesterone
2. ↑ tidal volume
3. resp rate ↑ 2 breaths/min
4. ↑ awareness to breath (gotta catch my breath)
5. sensitivity in medulla to CO2-↑ depth, rate
Term
What happens to the basal metabolic rate during pregnancy?
Definition
1. ↑ 15-20% by term
2. reflects ↑ in oxygen demand
3. may experience heat intolerance R/T excess
heat from ↑ BMR
(Labor room will be warm)
Term
What happens to the acid base balance during pregnancy?
Definition
1. pregnancy is a state of resp. alkalosis compensated by mild metabolic acidosis
2. facilitates maternal-fetal O2-CO2 transfer
Term
What should you remember when putting in a foley catheter on a pregnant woman?
Definition
The urethra has lengthened. Once you get flash of urine advance the foley a few more inches before inflating the balloon to avoid damaging the urethra.
Term
What does ↑ estrogen and progesterone do to uterus size & blood volume?
Definition
↑ estrogen and progesterone
Term
What causes larger amounts of urine during pregnancy?
Definition
Dilations of ureters, pelvis, renal calyces
Term
What are reasons for increased bacteria in the bladder?
Definition
1. Urine flow rate slowed→stasis/stagnation
2. Tubular reabsorption is impaired→glucose ↑ in urine→ more alkaline urine
Term
What causes increase in urinary frequency?
Definition
↑ in bladder sensitivity and compression from uterus
Term
At what trimester is the bladder pulled up into the abdomen?
Definition
2nd trimester
Term
What is a functional change in the renal system during pregnancy?
Definition
↑ in GFR,
Term
What is the most efficient position a pregnant woman to be to increase kidney perfusion?
Definition
Left lateral position
Term
What are the two things you are looking for when you dip a patient's urine and how often should you do a urine dip?
Definition
Urine dip every visit and look for:
1. Protein (preeclampsia) +1 is ok
2. Glucose (gestational diabetes)
Term
What could cause excessive edema during pregnancy?
Definition
Excessive Na intake
Term
What is needed to maintain normal Na level?
Definition
Increased tubular reabsoprtion
Term
Less blood flow causes pooling of fluids in the legs, how can this be corrected?
Definition
Elevate the legs or use diuretics but elevating is a better approach.
Term
What causes hyperpigmentation during pregnancy?
Definition
Caused by stimulation of anterior pituitary
hormone melanotropin. Darkening of nipple, areola, vulva, thighs
Term
What is chloasma?
Definition
brownish facial pigmentation-intensified by sun
-usually fades after pregnancy
Term
What is linea nigra?
Definition
dark vertical line from symphysis pubis to fundus that starts as linea alba-before pigmentation but is not present in all pregnant women
Term
What is striae gravidarum?
Definition
Stretch marks on abdomen, breasts, thighs caused by separation of collagen. 50-90% of women will have this.
Term
What are other changes that occur in pregnancy?
Definition
1. angiomas-vascular spiders
2. palmar erythema-blotches on hands
3. pruritus-itching from the inside out
4. gum hypertrophy-bleeding gums
accelerated nail growth
5. hirsutism-excessive hair growth
6. ↑ blood supply = ↑ perspiration
Term
How can you treat pruritus?
Definition
Change soap, use lotion, Benadryl, different detergents
Term
What do you need to check if a pregnant mother has bleeding gums?
Definition
If she is brushing her teeth. If not give her a softer tooth brush. Also check the calcium levels. The baby may be taking calcium from the mom.
Term
What happens to the back of a pregnant woman?
Definition
Lordosis increases for balance
Term
How much can the pelvis open when relaxin is in her system?
Definition
1/4 inch cartilage separation
Term
What can happen to the abdominal muscles in pregnancy?
Definition
(diastasis recti abdominis) Separation of the abdominal muscles. Exercise can help the muscle come back together.
Term
What is sciatica & how can it be treated?
Definition
Pressure on the pelvic nerve caused by the pregnancy creates pain that radiates down one leg. Abdominal sling & support garments can be used to reduce pressure.
Term
What does dependent edema cause?
Definition
Carpel tunnel;
burning, paresthesia, pain in the hand, radiating to the elbow
Term
What happens to a pregnant woman that has a history of migraines?
Definition
they get worse due to increase blood flow
Term
What are two neurological adverse effects that can happen from pregnancy?
Definition
Tension headaches, syncope (early stages)
Term
What GI negative effects does pregnancy cause?
Definition
Constipation, Nausea, vomiting, hiaitial hernias
bleeding of gums/problems of the mouth
-caused by rising level of estrogen
-ptyalism-excessive salivation
Term
When estrogen increases what happens to HCl?
Definition
It decreases
Term
What happens when progesterone goes up?
Definition
Stomach emptying time decreases & heartburn can occur
Term
What can a pregnant woman do to reduce heartburn?
Definition
Avoid spicy foods, take Tums (increases calcium as well), sit up after meals, small frequent meals-> keep stomach full to have continuous emptying
Term
What are the effects of gallbladder distention?
Definition
Prolonged emptying time and thickening of bile→development of gall stones & can lead get into the skin causing pruritus gravidarum (pups)
Term
What are some change in appetite/food consumption?
Definition
1. change in CHO, protein, fat metabolism
2. pica-craving for non-food material
3. morning sickness-usually ends by 2nd trimester
Term
Why does morning sickness end by the 2nd trimester?
Definition
The placenta has taken over hormonal control
Term
Endocrine system in a pregnant woman
?
Definition
Work
Term
What are the ↑ secretions of pituitary hormones during pregnancy?
Definition
thyrotropin
FSH/LH
prolactin
vasopressin (antidiurectic hormone)
oxytocin
Term
What are the ↑ secretions of thyroid hormones during pregnancy?
Definition
thyroxine
triiodothyronine
Term
What is released from the parathyroid during pregnancy?
Definition
↑ secretion of parathyroid hormones
Term
What is released from the adrenal glands during pregnancy?
Definition
cortisol-r/t ↑ estrogen-regulates CHO/prot meta.
Aldosterone-protective response to Na excretion
Term
What is secreted from the pancreas during pregnancy?
Definition
insulin is ↑
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