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Phys. Exam 4 Post. Pituitary
Posterior Pituitary
16
Physiology
Graduate
12/03/2010

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Term
The posterior pituitary stores what hormones?
Definition
- vasopressin
- oxytocin
Term
In the breast, there are millions of alveoli, most with sinuses. The area around the sinuses sends signals to the ___ ___ to stimulate hormone secretion. Oxytocin binds to _____ cells and causes them to contract so milk is pushed down into the sinuses.
Definition
- anterior hypothalamus
- myoepithelial cells
Term
Parturition:
Definition
- when its time for delivery, the uterus contracts, stretches the cervix, which signals the anterior hypothalamus
- positive feedback mechanism
Term
The uterus is ready for parturitiion when estrogen increases what two things?
Definition
- estrogen increases uterine prostaglandin synthesis
- estrogen increases uterine oxytocin receptors
Term
Intercourse stimulates the cervix to send signals to release ___. This hormone appears to be important for the transport of sperm through the reproductive tract.
Definition
oxytocin
Term
Vasopressin aka ____ ___ ___ increases when:
Definition
- antidiuretic hormone (ADH)
- increases when osmolarity rises due to dehyrdation or salt intake
- increases when blood volume falls due to dehydration or blood loss
Term
There are osmoreceptors near the ____.
Definition
hypothalamus
Term
Where are volume receptors?
Definition
- in the aorta, superior vena cava, etc.
- when blood volume falls, vasopressin is secreted
Term
ADH increases:
Definition
- water reabsorption via increased aquaporins
- blood pressure
Term
Water reabsorption occurs in the ___ ___ via ___ receptors.
Definition
- distal nephron
- V2
Term
How does ADH increase blood pressure?
Definition
- increases resistance which in turn increases pressure

- arterioles: deltaP= F X R
Term
Too little ADH causes ___ ___.
Definition
Diabetes Insipidus
- idiopathic
- may be caused by trauma, surgery, compression, infarction
- Nephrogenic DI
- Drugs and alcohol
- Psychogenic polydipsea
Term
Examples of causes for Diabetes Inspidus:
Definition
- car crash where nasal bone destroys pituitary
- tumor blocking pituitary
- Lithium used to treat bipolar disease> ADH receptors don't work anymore
- Nephrogenic DI: genetic defect where ADH receptors never developed
- Psychogenic polydipsia: drinking lots of water b/c think something is wrong with them and want attention
Term
Excessive ADH secretion is aka :
Definition
- Syndrome of Inappropriate ADH secretion (SIADH)
Term
Causes of excess ADH secretion:
Definition
- non-pituitary tumors (lung cancer tumor may cause excess ADH secretion and hypertension)
Term
Effects of excess ADH secretion:
Definition
- low plasma osmolarity
- normal to high blood volume
-
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