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Phys Adapt
Chapter 3
49
Biology
Undergraduate 4
09/20/2007

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Term
Solute
Definition
dissolved material
Term
Transport
Definition
general way to any and all movements of solutes or water across cell membranes or epithelia
Term
Equilibrium
Definition
state toward which an isolated system undergoes change, it is not able to change in all conceivable ways.
Term
Isolated system
Definition
have no inputs or outputs of energy
Term
Passive-transport mechanisms
Definition
capable of carrying material only in the direction of equilibrium.
Term
Active-transport mechanism
Definition
can carry material in the direction opposing equilibrium.
Term
Simple solute diffusion
Definition
transport that arises from the molecular agitation that exists in all systems above absolute zero and from the simple statistical tendency for such agitation to carry more molecules out of regions of relatively high concentration than into such regions.
Term
J = D ((C1-C2)/X)

J=rate at which solute diffuses
C1-C2=difference in concentration
(C1-C2)/X=concentration gradient
D=diffusion coefficient
Definition
Fick diffusion equation
Term
Bulk solution
Definition
solution that is away from contact with a membrane. Net charge of bulk solution is 0 or equal.
Term
Ion channels
Definition
Integral membrane proteins that transport ions through cell membranes.
Term
Gated channels
Definition
form of ion channel that can open and close because the proteins of which they are made of are able to undergo conformational changes that cause their central passage way to increase or decrease the ease with which ions pass.
Term
Voltage gated channels
Definition
open and close to response in changes in the voltage difference across a membrane. (nerves)
Term
Stretch gated channels
Definition
open and close in response to stretching or pulling forces that alter tension on membrane.
Term
Phosphorylation gated channels
Definition
open or close according to whether the channel proteins are phosphorylated.
Term
Ligand gated channel
Definition
act as receptors of extracellular signals and as ion channels.
Term
Permeability
Definition
- ease of which a solute can move through the membrane by diffusion
Term
Selective permeability
Definition
permits some solutes to pass through by diffusion with greater ease than others.
Term
Electrical gradient
Definition
difference in voltage between the two sides of a membrane.
Term
Concentration effect
Definition
influence of concentration gradient across a cell membrane
Term
Electrical effect
Definition
influence of the electrical gradient on the ion’s diffusion
Term
Electro-chemical equilibrium
Definition
when a charged solute is at equilibrium across a membrane when the concentration effect on it diffusion and the electrical effect are equal but opposite.
Term
Donnan equilibrium
Definition
where a complex type of electrochemical equilibrium involving diffusion of multiple ions and water then tends to develop.
Term
Facilitated diffusion
Definition
Passive transport of the polar organic solutes across cell membranes occurs typically by the con covalent and reversible binding of the solutes to solute-specific transporter proteins in the membranes
Term
Active-transport mechanisms
Definition
capable of moving solutes away from electrochemical equilibrium.
Term
Uphill transport
Definition
alternative name for active transport
Term
Carrier-mediated transport
Definition
solute combines noncovalently and reversibly with a solute-specific transporter or carrier protein in the cell membrane.
Term
Transporter
Definition
a membrane protein that mediates active or passive transport across the membrane by binding noncovalently and reversibly with a solute.
Term
Ligands
Definition
solutes that bind noncovalently and reversibly with a transporter
Term
Electroneutral
Definition
do not generate an imbalance of charge across a membrane
Term
Electrogenic
Definition
mechanism that creates a charge imbalance across a membrane
Term
Na+-K+ pump
Definition
example of electrogenic mechanism.
Term
Na+-K+ATPase
Definition
transporter protein involved in active transport.
Term
Primary active transport
Definition
draws energy immediately from ATP
Term
Secondary active transport
Definition
draws energy, in an immediate sense, not from ATP, but from an electrochemical gradient of a solute such as Na+.
Term
Contransport
Definition
transporter protein moves two solutes in coupled fashion in one direction (contransporter).
Term
Countertransport
Definition
transporter moves two solutes in coupled fashion in opposite directions (countertransporter).
Term
Colligative properties
Definition
properties that depend simply on the number of dissolved entities per unite volume rather than the chemical nature of the dissolved entities.
Term
Osmotic pressure
Definition
property of a solution that allows one to predict whether the solution will gain or lose water by osmosis when it undergoes exchange with another solution.
Term
Freezing point
Definition
highest temperature capable of inducing freezing
Term
Water vapor pressure
Definition
the tendency of a solution to evaporate.
Term
Freezing-point depression
Definition
the difference between the actual freezing point of a solution and the freezing point of pure water.
Term
Water vapor pressure depression
Definition
difference between a solutions’ water vapor pressure and the water vapor pressure of pure water
Term
Semi-permeable membrane
Definition
membrane permeable to only water.
Term
Osmosis
Definition
the passive transport of water across a membrane, which can be a cell membrane, an epithelium, or an artificial membrane
Term
ratio (∏1-∏2)/X
Definition
Osmotic gradient
Term
Osmotic permeability-
Definition
- permeability of the membrane to osmotic water transport.
Term
Isosmotic
Definition
when two solutions have the same osmotic pressure.
Term
Hyposmotic
Definition
- when a solution has a lower osmotic pressure than another.
Term
Hyperosmotic
Definition
when a solution has a higher osmotic pressure than another
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