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PHM - Exam 3 - Absorption/Distribution
N/A
44
Medical
Graduate
06/08/2013

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Cards

Term
Vancomycin
Definition
not absorbed from GI tract; IV administration. Distributed to most body fluids. NO CNS
Term
Bacitracin
Definition
not absorbed from GI tract; topical administration
Term
Penicillins
Definition
IM and IV administration
Term
Cephalosporins (3rd gen: Cefotaxime, Cefixime)
Definition
CNS
Term
Cephalosporins (1st gen: Cephalexin)
Definition
oral
Term
Cephalosporins (1st gen: Cepazolin)
Definition
IM
Term
beta-lactam (Carbapenems and Monobactams)
Definition
IV administration; former given with cillistatin (renal enzyme inhibitor to prevent renal metabolism)
Term
Polymyxin
Definition
NO GI absorption, so used to decrease bowel flora prior to surgery; topical administration
Term
Polymyxin (Amphotericin B)
Definition
IV administration
Term
Polymyxin (Nystatin)
Definition
topical; cause highly nephrotoxic
Term
Azole Antifungals
Definition
oral
Term
Azole Antifungals (Fluconazole)
Definition
CSF; can be administered IV
Term
5-Fluorocytosine Antifungals
Definition
oral, CSF
Term
Fluoroquinolones
Definition
Oral; IM; IV
Term
Rifampin
Definition
GI; can be given IM; IV; distributed in total body water (ORANGE TINT)
Term
Aminoglycosides
Definition
IM; IV; SC; poor lipid solubility (poor CNS)
Term
Tetracyclines
Definition
oral/parentral (NOT IM--> too irritating)
Term
Chloramphenicol
Definition
distributes to total body water; CSF---> meningitis;
Term
Macrolides (Erythromycin)
Definition
doesn't penetrate BBB
Term
Macrolides (Azithromycin)
Definition
longer t1/2 and higher tissue concentration---> more desirable than Erythromycin
Term
Macrolides (Telithromycin)
Definition
oral
Term
Retapamulin
Definition
topical
Term
Clindamycin
Definition
oral
Term
Quinupristin/Dalfopristin
Definition
IV;
Term
Linezolid
Definition
Oral
Term
Sulfonamides
Definition
oral; distributes to total body water; CNS
Term
Flucytosine
Definition
oral; distributes to total body water; CSF
Term
Nitrofurantoin
Definition
oral
Term
Methenamine
Definition
oral + mendelic/ascorbic acid---> lower urine pH
Term
Alkylating Agent (Chlorambucil)
Definition
oral
Term
Alkylating Agent (BCNU)
Definition
IV; lipid soluble---> CNS
Term
Cisplatin
Definition
IV
Term
antiviral (DNA viruses, nonretroviral): Antiherpes Virus (Acyclovir)
Definition
oral; topical; CSF
Term
antiviral (DNA viruses, nonretroviral): Antiherpes Virus (Gancyclovir)
Definition
oral; CSF??
Term
antiviral (nonretroviral): Antiinfluenza (Amantadine)
Definition
oral; CSF?
Term
antiviral (nonretroviral): Antiinfluenza (Oseltamavir)
Definition
oral; CSF?
Term
antiviral (nonretroviral): Antiinfluenza (Zanamivir)
Definition
oral; intranasal
Term
antiviral (nonretroviral): Interferons
Definition
IV
Term
antiviral (nonretroviral): Lamivudine
Definition
oral; distributes to total body water
Term
antiretroviral: Zidovudine (AZT)
Definition
oral
Term
antiretroviral: Nevirapine
Definition
oral
Term
antiretroviral: Efavirenz
Definition
oral
Term
antiretroviral: Efuviritide
Definition
SQ
Term
antiretroviral: Maraviroc
Definition
oral
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