Shared Flashcard Set

Details

Pharm -- GI
First Aid 2012 pp367-370
28
Medical
Graduate
02/08/2013

Additional Medical Flashcards

 


 

Cards

Term
-dine
Definition
H2 blocker
cross BBB, cimetidine/ranitidine decrease renal excretion of creatinine
Term
bismuth
Definition
binds to ulcer base providing protection!!
Term
sucralfate
Definition
binds to ulcer base providing protection!! requires acid to be active
Term
misoprotol
Definition
PGE1 analog
Term
diphenoxylte
Definition
bind opiate recpetors -- anti-diarrheal
Term
loperamide
Definition
bind opiate recpetors -- anti-diarrheal
Term
bismuth subsalicylate
Definition
decrease fluid secretion into bowel -- anti-diarrheal
Term
aluminum hydroxide
Definition
antacid
hypoK, constipation, phyoP, prox muscle weakness , osteodystrophy, seizures
Term
calcium carbonate
Definition
antacid
hypoK, hyperCa, milk-alkali syndrome
Term
magnesium hydroxide
Definition
osmotic/bulking laxative; antacid
hypoK, hyperMg -- decreased DTRs, cardiopulm arrest
Term
magnesium citrate
Definition
osmotic/bulking laxative
Term
polyethylene glycol
Definition
osmotic/bulking laxative
Term
lactulose
Definition
osmotic/bulking laxative
metabolites (lactic and acetic acid) promote nitrogen excretion at NH4+ in gut!!
Term
docusate
Definition
stool softeners --> emulsify with stool
Term
mineral oil
Definition
stool softeners --> emulsify with stool
Term
castor oil
Definition
irritants/stimulatants --> increased GI motility
Term
senna
Definition
irritants/stimulatants --> increased GI motility
Term
bisacodyl
Definition
irritants/stimulatants --> increased GI motility
Term
sulfasalazine
Definition
activated by colonic bacteria --> sulfapyridine + 5-ASA --> inhibits COX
Term
olsalazine
Definition
activated by colonic bacteria --> sulfapyridine + 5-ASA --> inhibits COX
Term
ondansetron
Definition
5-HT3 antagonist -- centrally acting anti-emetic
Term
promethizine
Definition
H1 antagonist --> decreased GI motility --> anti-emetic
Term
metoclopramide
Definition
D2 receptor antagonist --> activates vomiting reflex pathway?? --> increase GI motility (for DM and post-surgery gastroparesis)
CI in Parkinson's duh!!
Term
ursodiol
Definition
inhibits HMG CoA reductase, intestinal reabsorption of cholesterol, and cholesterol secretion in bile --> for gallstones and PBC
Term
chenodiol
Definition
inhibits HMG CoA reductase, intestinal reabsorption of cholesterol, and cholesterol secretion in bile --> for gallstones and PBC
Term
orlistat
Definition
inhibits pancreatic lipase
Term
sibutramine
Definition
neurotransmitter reuptake inhibitor (5-HT, DA, NE) --> increased satietysibutramine
Term
fenfluramine-phentermine
Definition
fenfluramine -- increased 5-HT
phentermine = methamphetamine isomer --> increased E/NE in braine
off market 2/2 increased valvular disease and pHTN
Supporting users have an ad free experience!