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PharmFinal/FunCohort
Final for Pharm
124
Nursing
Undergraduate 2
03/10/2011

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Cards

Term
What should be monitored in a patient receiving ANDROGENS? Why?
Definition
-HEMOGLOBIN & HEMATOCRIT should be monitored.

-Needs to be monitored because an adverse side effect of androgens in POLYCYTHEMIA
Term
Combining NITRO & _____________ can lead to serious HYPOTENSION
Definition
Tadalafil (Cialis)

HYPOTENSION
Term
After taking the first dose of this drug (it's specifically for males), the client may become HYPOTENSIVE
Definition
DOXAZOSIN
(CARDURA)
Term
TERAZOSIN
(HYTRIN)
1)Type of Drug?
2) Actions (2)
Definition
1) Alpha1-adrenergic blocker

2) a. Relaxes smooth muscle in prostate and b. can reduce blood pressure.
Term
2 common symptoms of
BENIGN PROSTATIC HYPERPLASIA
(BPH)
Definition
NOCTURIA
&
Non-Specific FULLNESS in the lower pelvis region.
Term
Which hormone regulates
SPERM PRODUCTION?
Definition
FOLLICLE-STIMULATING HORMONE
(FSH)
Term
How do drugs designed for
DYSFUNCTIONAL UTERINE BLEEDING
work (in the body)?
Definition
They inhibit the effects of estrogen in the uterus, thus restoring balance.
Term
How long is
DEPO-PROVERA
effective for?
Definition
3 MONTHS
Term
What is a common/adverse effect of
ZIDOVUDINE (RETROVIR)?
Definition
BONE MARROW SUPPRESSION
Term
What is an important ADVERSE effect of
GENTAMICIN?
(It can become permanent)
Definition
OTOTOXICITY
(becomes permanent with prolonged use)
Term
MILK products can REDUCE the EFFECTIVENESS of which drug?
Definition
Tetracycline
(No milk for 4 guys on a bike..hehe dumb way to remember)
Term
What is the best way to identify the causitive organism of a systemic infection?
Definition
BLOOD CULTURE TEST
Term
A HIGH FEVER is usually indicative of what? (Among a million other things)
Definition
A SYSTEMIC INFECTION
Term
Which drug used for pain, inflammation, fever INHIBITS Warfarin (Coumadin) METABOLISM?
Definition
ACETAMINOPHEN (TYLENOL)
Term
What is the MAX AMOUNT of IBUPROFEN (MOTRIN) that can be taken in 24 hours?
Definition
3,200 mg
Term
Should you take DARVOCET OR ADVIL for your ARTHRITIS pain, you old cogger.. Why?
Definition
ADVIL (Ibuprofen) should be taken because it is an anti-inflammatory.
Darvocet (Propoxyphene) is not as effective because it is NOT an anti-inflammatory
Term
BONE MARROW SUPPRESSION & LIVER DAMAGE can be caused by which type of drug?
Definition
IMMUNOSTIMULANTS
Term
BLOOD DYSCRASIA is an adverse effect of what therapy (med)?
Definition
IMMUNOSTIMULANT
Term
If a patient is taking
CYCLOSPORINE (NEORAL) they should not consume what? Why not?
Definition
GRAPEFRUIT because it increases the drug's level in the blood.
Term
How often doe the extended release/sustained form of
METFORMIN (GLUMETZA) need to be taken?
Definition
Only ONCE A DAY
Term
3 major advantages of
METFORMIN?
Definition
1) Most side effects are MINOR; mainly GI RELATED
2) Does not cause hypoglycemia
3) Does not cause weight gain
Term
Patient's taking
IMMUNOSUPPRESSANTS
should avoid?
Definition
CROWDS
(No New Kids Reunion or Charlie Sheen show for you buddy..)
Term
These type of drugs SUPPRESS the IMMUNE RESPONSE so the nurse will need to ASSESS FOR INFECTION
Definition
CORTICOSTEROIDS
Term
Combining this drug with ALCOHOL will produce a DISULFIRAM (ANTABUSE) like reaction
Definition
LEVAMISOL (ERGAMISOL)

U shoulda LEVA alcohol alone ERGA..
(Wow, my memory tricks are getting pretty bad, huh?)
Term
Which Anti-diabetic (hypoglycemic) drug
does NOT promote insulin release from pancreas?
Definition
METFORMIN (GLUCOPHAGE)
Term
METFORMIN (GLUCOPHAGE)
1) What class is it in?
2) 2 forms it comes in?
3) Mechanism of Action?
Definition
1) BIGUANIDES class
2) Immediate release & Extended or Sustained release
3) Decreases hepatic production of glucose (gluconeogenesis) and reduces insulin resistance
Term
What is the only drug in the
BIGUANIDE class?
Definition
METFORMIN (GLUCOPHAGE)
Term
How long is DEPO-PROVERA effective for?
Definition
3 months
Term
How do drugs designed for
DYSFUNCTIONAL UTERINE BLEEDING
work in the body?
Definition
They INHIBIT the effects of ESTROGEN in the UTERUS; thus restoring balance..
Term
Which HORMONE regulates
SPERM PRODUCTION?
Definition
FOLLICLE-STIMULATING HORMONE (FSH)

*Sperm are like little FiSH
Term
2 common symptoms of
BENIGN PROSTATIC HYPERPLASIA (BPH)
Definition
Nocturia
&
Non-specific fullness in lower pelvis region
Term
TERAZOSIN (HYTRIN)
1. Type of drug?
2. Actions in the body (2)
Definition
1. ALPHA1-ADRENERGIC BLOCKER

2. Relaxes smooth muscles in the Prostate &
can also lower B/P
Term
What are the GENERIC and BRAND names for a drug used to promote hair growth?
Definition
Generic: FINASTERIDE (PROSCAR)
Brand: PROPECIA
Term
After taking the first dose of this drug (spec. for males), the client may become HYPOTENSIVE
Definition
DOXAZOSIN (CARDURA)
Term
What happens to the body when
OXYTOCIN is given post-partum?
Definition
The smooth muscle of the uterus contracts
Term
Which PEPTIC ULCER MEDICINE is sometimes used to TERMINATE PREGNANCY? (Thus also contraindicated during pregnancy)
Definition
MISOPROSTAL (CYTOTEC)
Term
What is an expected effect of
IRON (FERROUS SULFATE) therapy?
Definition
Darkened Stools
Term
What are the
4 FAT SOLUBLE VITAMINS?
What is DANGEROUS about them?
Definition
VITAMIN'S A, D, E & K

-They can be STORED in large quantities in the LIVER & ADIPOSE TISSUE = Leads to dangerously HIGH LEVELS
Term
PHENOTHIAZINES
1. What do they BLOCK?
2. What can they cause?
Definition
1. They block DOPAMINE
2. Can cause DRY MOUTH
Term
2 actions of ANTIDIARRHEALS
(such as ATROPINE)
Definition
1. SLOW PERISTALSIS
2. ALLOW WATER ABSORPTION
Term
What is the ANTIDOTE for
PERCHLORPERAZINE (COMPAZINE)?
When is it taken?
Definition
-Antidote: An ANTICHOLINERGIC drug such as BENZTROPINE (COGENTIN)
-Taken when client is experiencing DYSTONIA (sustained muscle contractions, twisting, abnormal postures and repetative movements)
Term
DYSTONIA
1. What is this?
2. What drug may cause this as an extrapyramidal side effect?
3. What is the antidote?
Definition
1. Sustained muscle contractions, twisting, abnormal postures & repetative motions.
2. PERCHLORPERAZINE (COMPAZINE) can cause.
3. Antidote: An ANTICHOLINERGIC DRUG such as BENZOTROPINE (COGENTIN)
Term
PERCHLORPERAZINE
(COMPAZINE)
What type of drug is this?
Definition
PHENOTHIAZINE
DRUG
Term
OPIOID that is unique because it
DOES NOT HAVE ANALGESIC PROPERTIES
Definition
ATROPINE
(LOMOTIL)
Term
When a patient is taking
METAMUCIL (MUCILLOID)
what must they do?
Definition
INCREASE FLUID INTAKE
Term
(Think pH/homeostasis for this one)
1. What 3 things WILL NOT occur as a result of vomiting?
2. What WILL OCCUR & why?
Definition
1. Respiratory acidosis, Respiratory alkalosis and Metabolic acidosis WILL NOT OCCUR as a result of vomiting.
2. METABOLIC ALKALOSIS WILL OCCUR due to excessive loss of HYDROCHLORIC ACID from the stomach.
Term
BOWEL PREP
(DEFINITION)
Definition
A medication and a process
-MEDICATIONS such as LAXATIVES that are used to "clean a patient out".
-Process used to clean colon with enemas &/or special drinks, laxatives.
Term
When is
BOWEL PREP
indicated (3 procedures)?
Definition
Indicated prior to
COLON SURGERY
COLONOSCOPY
BARIUM X-RAY
Term
When using a BOWEL PREP the client must be able to what?
-Due to this, what must be ASSESSED?
Definition
-Client must be able to
EXCRETE LARGE AMOUNTS OF FLUID
therefore
KIDNEY FUNCTION & CREATININE LEVELS must be assessed. (This is CRITICAL prior to giving Bowel Prep)
Term
After giving
SIBUTRAMINE (MERIDIA)
the nurse must assess for? Why?
Definition
Nurse must assess the client's
BLOOD PRESSURE
because HTN is a side effect of
sibutramine (Meridia)
Term
CHRONIC
PANCREATITIS
1. Eventually leads to?
2. What treatment will be needed?
Definition
1. Will lead to PANCREATIC INSUFFICIENCY
2. May need to replace PANCREATIC ENZYMES
Term
Can H2 RECEPTORS BLOCKERS be taken with FOOD?
Definition
Yes, they can be taken WITH or WITHOUT FOOD.
Term
SUCRALFATE
(CARAFATE)
1. Class?
2. What does it do?
(I.E. why can't take with food, milk, H20)
Definition
1. ANTIULCER, GASTROADHESIVE
2. Drug & gastric acid blend to create a viscous, adhesive, paste-like substance that protect damaged mucosa against further destruction from additional H+ acid, ulcergenic secretions.
*If excess food, milk, H20 present then PASTE CAN'T FORM
Term
PROTON PUMP INHIBITORS
Mechanism of Action
Definition
Reduces acid secretion in stomach
Term
RANITIDINE (ZANTAC)
1. Class?
2. Mechanism of Action?
3. Primary Use?
4. Adverse Effects (2)?
Definition
1. H2-RECEPTOR BLOCKER
2. Blocks H2 receptors in stomach to decrease acid production
3. Treat peptic ulcer disease
4. -Possible reduction of RBC, WBC & Platelet counts
-Impotence of loss of libido in men
Term
H2-RECEPTOR BLOCKERS
(Name 4 brands)
Definition
1. Zantac
2. Tagament
3. Axid
4. Pepcid
Term
What are the drugs of FIRST CHOICE to TREAT PEPTIC ULCERS?
Definition
H2-RECEPTOR BLOCKERS
Term
SUCRALFATE (CARAFATE)
1. What does it do?
2. 4 things to consider in regards to administration
Definition
1. Provides a protective coating
2. Should be administered before meals
-Administering sucralfate after meals will inhibit it's ability to adhere to the ulcer.
-Administering with milk will inhibit it's action
-Administering with 8 oz. of water will decrease it's bioavailability and effectiveness
Term
Even after a patient is given MEDS TO CONTROL MELANA AND/OR A GI BLEED, a patient may still what?
Definition
They may still experience PAIN for several days.
Term
MELANA (OR MELENA) COULD INDICATE _______ _________ & should be reported immediately
Definition
GI BLEEDING
Term
Define
MELANA (OR MELEANA, MELENA - I've seen all differ. spellings)
Definition
BLACK, TARRY STOOLS
Term
If a patient has been taking
GERD MEDICATIONS for a long time & is showing S & S of ANEMIA, FATIGUE & WEAKNESS, what might you suspect the causative agent to be?
Definition
-Their stomach may no longer be able to absorb Vit B12.
-They may have pernicious anemia.
(All side effects of CHRONIC SUPPRESSION of STOMACH ACID)
Term
2 ADVERSE EFFECTS of taking GERD MEDICATIONS on a LONG TERM BASIS? (Chronically suppressing stomach acid)
Definition
-Stomach may not be able to absorb Vit B12
-There is possibility of PERNICIOUS ANEMIA
Term
3 common signs of PERNICIOUS ANEMIA OR VIT. B12 DEFICIENCY
Definition
1. ANEMIA
2. FATIGUE
3. WEAKNESS
Term
What type of drug is
NEXIUM?
Definition
PROTON-PUMP INHIBITOR
Term
PROTON-PUMP INHIBITORS
VS.
H2-RECEPTOR ANTAGONISTS
Definition
PROTON PUMP INHIBITORS reduce acid secretion to a greater extent and have a longer duration of action than H2-Receptor Antagonists.
Term
If a patient is given OXYTOCIN (PITOCIN), what should be assessed for and why?
Definition
HEADACHE
-This side effect could indicate HYPONATREMIA due to water intoxication and their FLUID BALANCE should then be assessed.
Term
CLOMIPHENE (CLOMID)
1. What does it stimulate?
2. This stimulation results in?
Definition
Stimulates LEUTEINIZING HORMONE (LH), which results in the MATURATION of more OVARIAN FOLLICLES than would normally occur.
Term
How is PROSTATE CANCER treated/controlled?
Definition
ESTROGENS are administered to suppress androgen secretion.
*Prostate cancer is usually dependent on androgens for growth
Term
What is the mechanism of action of REGULAR INSULIN
(How does it work?)
Definition
Regular insulin promotes entry of glucose into the cells, thereby lowering glucose.
Term
What is the only insulin that can be given IV?
Definition
REGULAR
Term
What does INSULIN do to POTASSIUM in the body? This may cause?
Definition
Insulin causes POTASSIUM to move into the cell and may cause HYPOKALEMIA
Term
TYPE II DM, what happens in the body (in regards to insulin)
Definition
The PANCREAS produces INSULIN,
but the CELLS CANNOT USE it.
Term
3 actions that need to be taken by the nurse when they find a DM Type I patient UNRESPONSIVE?
Definition
1. The nurse must act immediately (BEFORE CALLING DOC) to treat HYPOGLYCEMIA
2. Assessment for ABC's should be done prior to calling a CODE
3. The vital signs are taken AFTER the patient has been treated for HYPOGLYCEMIA
Term
If you find a DM TYPE I patient unresponsive, you should treat for ______ rather than __________
Definition
HYPOGLYCEMIA rather than HYPERGLYCEMIA
Term
How often is
LANTUS INSULIN
usually prescribed
Definition
ONCE-A-DAY
Term
How must INSULIN LIPRO (HUMALOG) be given? Why?
Definition
Must be given with food to prevent HYPOGLYCEMIA.
*The onset of action for this glucose is only 10-15 minutes.
Term
What is the primary goal of pharmacotherapy in
HYPERTHYROIDISM (GRAVE'S DISEASE)?
Definition
To LOWER the ACTIVITY of THYROID HORMONE
Term
HYPERTHYROIDISM is
A.K.A.
Definition
Grave's Disease
Term
2 Drugs used to treat
DIABETES INSIPIDUS
Definition
Vasopressin & Lypressin
Term
What is important to know if you are taking GLUCOCORTICOIDS (as far as administration)
Definition
The drug must be taken at the SAME TIME OF DAY to maintain serum levels
Term
When a client is receiving GLUCOCORTICOID therapy, the nurse should assess for? Why?
Definition
-HYPERTENSION
-The medications can INCREASE ANGIOTENSIN II production?
Term
ALDOSTERONE effects from ADRENAL MEDS (i.e. mineralcorticoid activity)
1. Causes?
2. Which can result in?
Definition
1. Sodium & Fluid retention and Increased Blood Glucose due to promotion of gluconeogenesis
2. Hypernatremia & Hyperglycemia
Term
Adverse effect of
LEVOTHYROXINE (SYNTHOID)?
What is a necessary assessment that needs to be made if patient is taking?
Definition
INSOMNIA

Nurse must assess for ALTERED SLEEP PATTERNS
Term
VASOPRESSIN (PITRESSIN)
-This is the same as?
-Acts on?
Definition
1. Same as ADH (ANTI-DIURETIC HORMONE)
2. Acts on the collecting ducts in the kidneys to increase water absorption
Term
Why is FOLIC ACID so important during PREGNANCY?
Definition
It is ESSENTIAL for the PREVENTION of NEURAL TUBE DEFECTS in a fetus.
Term
Clients with LOW MAGNESIUM LEVELS will be at risk for?
Definition
SEIZURES; related to preeclampsia. (Look for a decrease in Deep Tendon Reflexes)
Term
If a patient is exhibiting seizures (related to preclampsia) and/or decreased deep tendon reflexes, what might you suspect?
Definition
Low Magnesium Levels
Term
What DEFICIENCY will ALCOHOLICS commonly have?
Definition
THIAMINE DEFICIENCY
Term
What is used to detect or provide information about VITAMIN A TOXICITY? Why?
Definition
SERUM ALBUMIN LEVEL because BINDING PROTEINS can become SATURATED WITH VITAMIN A
Term
When should a
VITAMIN K injection
be used on an
INFANT?
Definition
BEFORE bleeding is observed.
(Newborns routinely receive VITAMIN K shots shortly after birth)
Term
How should BLOOD CLOTTING be promoted in INFANTS?
Definition
With a VITAMIN K STIMULUS INJECTION (liquid form WILL NOT work)
Term
Will BREAST FEEDING PROTECT an INFANT from BLEEDING (i.e. excessive, hemorrhage)?
Definition
NO - because Vit. K is not present in high enough amounts in breast milk
Term
An INFANT'S GUT IS STERILE, therefore..
Definition
There is not enough bacteria to synthesize Vit. K (which is essential to promote blood clotting). This is why they get the Vit. K injection
Term
What are used to soften/eliminate
CERUMEN?
Definition
WAX SOFTENERS
(Hard one, I know...)
Term
These drugs DILATE THE PUPIL for BETTER VISUALIZATION
Definition
MYDRIATICS
Term
What type of drugs DECREASE PRODUCTION OF AQUEOUS HUMOR?
Definition
BETA-ADRENERGIC BLOCKERS
Term
3 ADVERSE effects of
PROSTAGLANDINS
Definition
1. Eye Pain
2. Eye Burning
3. Dry Eyes
Term
With what GLAUCOMA drug is the use of OTC COLD REMEDIES CONTRAINDICATED & why?
Definition
TIMOLOL (TIMOPTIC) because the OTC's can contain sympathetic nervous system drugs that can interact with Timolol
*Bulgy-eyed Timmy can't take cold medicine!
Term
What drugs are used to treat MIDDLE EAR INFECTIONS?
Definition
SYSTEMIC ANTIBIOTICS
Term
How should you administer Eye Drops?
Definition
Place the drop in the CONJUNCTIVAL SAC below the eye
Term
Which class/type of drugs can CONTRIBUTE TO GLAUCOMA?
Definition
ANTICHOLINERGICS
Term
Which types of EYE DROPS would be used if you want to INSPECT THE RETINA?
Definition
CYCLOPLEGIC EYE DROPS
Term
CYCLOPLEGIC EYE DROPS do what to the eye? Why is this important?
Definition
They dilate the pupil and PARALYZE THE CILIARY MUSCLE.
Important because the paralyzation of the ciliary muscle is necessary for visualization of the retina.
Term
Which Skin Disorder drug is contraindicated in clients with a known Seizure Disorder?
Definition
KWELL (LIDANE)
Term
Best way to treat
PSORIASIS
(How/with what?)
Definition
Apply a TOPICAL CREAM with a GLOVED hand
Term
Parent's whose children are taking ISOTRETINOIN (ACCUTANE) must watch for? Why?
Definition
They must watch for mood changes/DEPRESSION because this drug can lead to SUICIDAL IDEATION
Term
Which skin disorder drug can lead to SEVERE DEPRESSION; even SUICIDAL IDEATION?
Definition
ISOTRETINOIN
(ACCUTANE)
Term
Which skin disorder drug must be left on the body for 8-12 hours in order to be effective?
Definition
KWELL
Term
When a client is taking this drug, MUSCLE SPASMS & FACIAL TWITCHING must be reported IMMEDIATELY & why?
Definition
ALENDRONATE (FOSAMAX)
-These signs indicate LOW CALCIUM LEVELS & this must be reported before the patient has SEIZURES.
Term
2 indicators of a FOSAMAX induced
LOW CALCIUM LEVEL ?
Definition
MUSCLE SPASMS AND FACIAL TWITCHING
Term
If a patient is receiving an IV of CALCIUM, what must be assessed and why?
Definition
The site must be assessed because EXTRAVASATION may lead to TISSUE NECROSIS at the insertion site
Term
Low levels of ________ will put a patient at RISK FOR SEIZURES
Definition
CALCIUM
Term
What is the BEST assessment tool to determine the effectiveness of
ETIDRONATE DISODIUM (DIDRONEL)
Definition
BONY DENSITY

*DID ETID get her bone density scan?
Term
3 signs of
COLCHICINE (COLSALIDE) TOXICITY
Definition
1. Nausea
2. Vomiting
3. Abdominal Pain
Term
With what joint disorder drug must a patient get regular eye exams and why?
Definition
HYDROXYCHLOROQUINE SULFATE (PLAQUENIL)
because it can cause BLURRED VISION, INABILITY TO READ & VISUAL FIELD DISTURBANCES.
Term
HYDROXYCHLOROQUINE SULFATE (PLAQUENIL)
-What is this drug used for?
-What are some adverse effects (3)?
Definition
-Used for rheumatoid arthritis
-Can cause blurred vision, inability to read, and visual field disturbances
Term
What are the only 2 types of drugs contraindicated with the use of
RALOXIFENE (EVISTA)?
Definition
ANTILIPIDS AND HORMONES
Term
TAMOXIFEN (NOLVADEX) is used with what disease and why?
Definition
BREAST CANCER
Used because the drug BLOCKS ESTROGEN
receptors, therefore the tumor is deprived of estrogen

*My aunt Tami blocked her estrogen and no longer has breast cancer..
Term
BREAST CANCER is dependent on what for growth?
Definition
ESTROGEN
Term
VIRAL
LOAD
Definition
A test that gives an ACTUAL COUNT of viral presence and is the BEST TEST
Term
SERUM CREATININE
should be monitored with which anti-viral drug? Why?
Definition
ACYCLOVIR (ZOVIRAX)
-The drug is NEPHROTOXIC
Term
What test should be performed on patients taking ZIDOVUDINE (RETROVIR) & why?
Definition
WBC COUNT
-The drug can cause BONE MARROW SUPPRESSION
Term
ZIDOVUDINE = what test?
vs.
ACYCLOVIR ='s what test?
Definition
ZIDOVUDINE = WBC COUNT
&
ACYCLOVIR = serum CREATININE
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