Aspirin

Class

Mecanism of Action 

Indications Uses 

Antiplatelet

Inhibits Prostaglandin and TXA2 Synthesis

Irreversible Acetylation of COX Isoenzymes 

Antiplatelet to decrease clotting

MI/Acute Coronary Syndromes

Pain, Fever, Inflammation Relief 

Dipyridamole/Persantine

Class

Mechanism of Action 

Indications and Uses 

Antiplatelet

Phosphodiesterase Inhibitor

Decreases TXA2 and Synthesis and Release 

Clotting Diseases 

Clopidogrel/Plavix

Class

Mechanism of Action

Indications/Uses 

ADP Receptor Antagonist

Prevents ADP mediated platelet activation of

GP IIb/IIIa Receptors 

Antiplatelet to Decrease Clotting

Acute MI/Acute Coronary Syndromes 

Abciximab, RePro/Tirofiban-Aggrastat

Class

MOA

Indications 

Glycoprotein IIb/IIIa Receptor Antagonist

Bind to the Glycoprotein (GP) IIb/IIIa receptor of human platelets.

Decreases platelet aggregation.

Antiplatelet actions to decrease clotting

Acute MI/Acute Coronary Syndromes