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Definition
D1, B1, a1 agonist dilates renal and mesenteric positive intoropic but little effect on heart rate diuretic treats shock, renal failure, CHF |
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Definition
B1 ag increase HR and contractility CHF tachycardia is major adverse effect |
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Definition
A1 ag vasoconstrictor, decongestant, mydriatic, detumescent (reduces swelling) reflex bradycardia is side effect |
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Term
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Definition
A2 ag reduces sympathetic outflow to heart and causes vasodilation hypertension, pain causes bradycardia or rebound hypertension if withdrawn |
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Definition
B2 ag asthma supress premature labor
adverse: hyperglycemia, tachycardia at high doses |
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Definition
nonselective alpha/beta agonist heart rate stimulant, bronchodilator, CNS stimulant adverse--hypertension and inosomnia |
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Definition
indirect--promotes release of NE and DA and inhibits reuptake ADHD, narcolepsy similar cardiac effects to NE insomnia, abuste, |
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Definition
inhibits NE reuptake ADHD less abuse insomnia, tachycardia, suicidal thoughs |
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Term
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Definition
TREAT: hypertension, antidote to Epi, BPH, pheochromocytoma, reynaud's disease |
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Term
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Definition
Treat: hypertension, angina pectoris & MI, CHF, arrythmias, hyperthyroidism, glaucoma, migrain |
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Definition
a1 blocker dilates arteries and relaxes smooth muscle of bladder neck and prostate capsule no increase in HR treats hypertension adverse: fist dose at bedtime--first dose effect inhibits ejaculation, nasal congestion |
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Definition
a1 blocker little effect on bp bph dudes can pee abnormal 'jaculation don't use'em wit vasodilators for ED--extreme hypotension |
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Term
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Definition
non-selective beta adrenergic blocker competitive antagonist don't use in diabetics or with (initial) heart failure, or with asthma decreases heart rate and contractility initial increase in peripheral resistance due to B2 block B1-decrease renin release, promotes bronchoconstriction, inhibits glycolosis Adverse: bradycardia, asthma aggravation, sexual dysfunction, fatigue |
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Term
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Definition
B1 selective hypertension, CHF, MI |
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Term
OTHER properties of beta blockers |
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Definition
some block A1 too! differences in lipid solubility intrinsic sympathomimetic activity--only partial agonists--little effect on HR and CO local anesthetic due to ion channel blockade additional properties like vasodilation and antioxidant effects |
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