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Definition
Naturetin 2.5 - 5 (1) Avail only in combo with Nadolol |
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Aquatag Exna 12.5 - 50 (1) DC'd |
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Definition
Hygroton Hylidone 12.5 - 25 (1) |
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Definition
Microzide HydroDiuril 12.5 - 50 (1) max at 25 mg to ↓ SEs |
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Definition
Saluron Diucardin 25 - 50 (1) DC'd |
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Definition
Aquatensen Enduron 2.5 - 5 (1) |
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Definition
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Naqua Metahydrin 2 - 4 (1) DC'd |
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Definition
Mykrox Zaroxolyn 2.5 - 10 (1) |
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4 types of niacin & examples |
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Definition
1. IR (rx niacor, otc) 2. ER (rx niaspan) 3. Long-acting aka SR, CR, timed-release (otc slo-niacin)... not fda approved for lipid lowering 4. no-flush (otc) |
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Definition
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Do all niacin products work? |
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Definition
1. no-flush less effective 2. niacinamide not effective for lipid 3. IR, ER, LA all work |
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Definition
1. aka nicotinic acid, form of B3 2. inc HDL, decr LDL, tx niacin deficiency |
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Term
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Definition
1. usp/nsf certified or DIN # in canada 2. avoid LA (hepato tox) & no-flush (prob don't work) |
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Term
1. SEs? 2. Severity differences |
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Definition
1. flush w/in 2 hrs; stomach upset, heartburn, n/v/d; hepatox, gout, hyperglycemia at high doses (>2g/d) 2. flush (IR>ER>LA), hepat/gout/sugar (IR |
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Term
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Definition
1. 325mg aspirin 30 min before IR, 45-60 min before if use enteric coated asa 2. will decrease over time with use 3. shortly after taking avoid: hot showers, hot drinks, alcohol, spicey foods 4. take wf (also decr stomach upset) |
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Definition
vision problems, yellowing eyes or skin, muscle aches |
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How to dose when switching products? |
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Definition
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Definition
niacin (nicotinic acid) + niacinamide (nicotinamide) |
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Term
1. tx of niacin deficiency 2. tx lipid |
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Definition
1. niacin & niacinamide effective 2. niacin |
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Term
1. why no-flush not effective 2. why don't rec |
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Definition
1. no free nicotinic acid in prep 2. no evidence of better tolerated & prob less effective |
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Definition
severe gout, chronic liver dz, active pud, arterial bleed |
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Definition
hyperuricemia, diabetes (2g or less most likely ok) |
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Term
1. Niaspan & Niacor LFTs rec. 2. when to dc |
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Definition
1. prior to start, q6-12wks for 1st yr, then q6mo 2. LFTS show progression esp 3x uln & persistant |
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