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Pharmacy 400
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20
Health Care
Undergraduate 1
05/30/2007

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Term
MTMS
designed to:
services:
Definition
- OPTIMIZE THERAPEUTIC OUTCOMES
- IMPROVE MEDICATION USE
- REDUCE the RISK of ADVERSE DRUG EVENTS & drug interactions
- UP PATIENT ADHERENCE
- LOWER overall costs
SERVICES:
-pharmacists can only provide services allowed under their states pharmacy act
- selecting, initiating, modifying or administering medicatrions
- monitoring/evaluating a patient's response tot herapy & providing recommmendations for therapeutic chagnes
Term
Evidence of Need
Definition
1966 -> 4bil spent on pharm.
2003 - 180 bil (300 bil now)
patients 65+ take 5 drugs a day
66% of patients 65+ have at least 1 chronic med condition & tend to use multiple healtcare providers
Term
Medication Therapy Manage Services
Definition
-First time, Medicare will pay for pharmacist's patient care services
MTMS beneficiaries must:
-have multiple chronic illnesses
-take multiple drugs
-be liekkly to incur annual drug costs above a specified level ($4k in 06) (03, approx 16% of Medicare had drug exp. over $4k)
Term
MMA Standard Prescription Drug Coverage
Definition
- est monthly premium of $37
- annual deductible at $250
- 25 % copay between 251-2250
- no coverage from 2251-5100 (donught hole)
- 28 rx drug plans in Ohio
Term
Medicare Presription Drug Improvement & modernization Act of 2003
Definition
- addition of prescription drug to benefit under medicare part D (2006)
- opputunities for pharmacists to expand patient care services and receive compensation for this care
-defacto provider status for pharm
-chronic care improvemtn progams
Term
Susan Kucukarslan et al
Definition
2003
-pharmacists on General Medicine rounds (henry ford hospital)
-preventable ADE reduced 78%
-reduced ADE's from 26.5 to 5.7/1000 hospital days

150 recommendations/147 were enacted
Term
Lucian Leape et al
Definition
1999
- pharmacis participation of ICU team decreased ADE's by 66% (Adverse Drug Events)
-reduced ADEs from 10.4 to 3.5/1000
-annual savings of 270k
Term
Project ImPACT
Definition
-Improved Perstance & Compliancew w. Therapy
Amer Pharm Assoc
-26 comm based ambulatory care pharmacies
397 patients
93.6% medication thereapy "persistance" over time
90.1% med therapy "compliance" adherent
62.5% reached/maintained NCEP lipid

2-4xs better outcome
Term
Pharmaceutical Care
Definition
-responsibile provision of drug therapy for the purpose of achieving definite outcome that improve a patient's quality of life
- patient focused, outcomes oriented, pharmacist responsibility, comprehensive drug therapy management
Term
Institue of Medicine (IOM)
"To err is human building a safer healt system"
Definition
Advisory committee to congress
- IOM quality of health care in amer comm
- 98k/yr in US due to medical errors
Pharm decision support, pharm inclusion on rounds, available patient info, improving patient knowledge of treatment & side effects
Term
Paulozzi & Annest
Definition
2007
1999-2004 68% increase in deaths from unintentional drug poisoning

among the largest increases: ages 15-24

poisioning 2nd only to motor vehicle accidents as cause of death
Term
Phillips et al
Definition
1998
examined all US death certificates 1983-1993

2.57 fold inc. in deaths due to med errors

93 there were 7391 deaths
Term
Lazarou et al
Definition
1998
serious and fatal ADR's hospital patiens
39 prospective studies

serious ADRs 6.7% (over 2 mil in 94)
fatal ADRs 0.32% (100k patients in 94)
4th-6th leading cause of death over 30 years
Term
Bootman et al
Definition
1997
drug related morbidity & mortality in nursing homes

$7.6bil

$1.33 spent on DRP's for every $1.00 spent on drugs
Term
ERnst & Grizzle
Definition
2000
update on Johnson & Bootman's 1995 estimate

$977mean cost:treatment failure
$1105mean cost: new med problem
$177.4bil in 2000

DOUBLES JOHN & BOOTMAN 1995
Term
Drug Related Problems
Definition
untreated indications
improper drug selection, subtherapeutic dose, failure to receive drugs, overdose, adverse drug reaction, drug interactions

$76.6 bil/year
diabetes - $45.2 bil
cancer - $100 bil
cardiovascular - $117 bil
Term
Johnson & Bootman
Definition
1995
23.4% treatment failures
10.5% new med problems
6.5% both
28% of hospital admissions
Term
Contemporary Ethical Issues
Definition
emergency contraceptives (Plan B), oxycotin addiction, controlled substance in pharm, how to treat pain, conflicts of interests, healt dsparities, marijuana
Term
4 step model for ethical decision making in pharmacy practice
Definition
1 problem indentification
2 develop alternative courses of action
3 select 1 alternative course of action
4 consider objections to alternative selected
Term
Hippocratic Principle v Ohio Pharmacy Practice Act
Definition
-doing good/avoiding harm to the patient are the only morally relevant considerations

-corresponding responsibility = equally responsible for the peron's "appropriatenes" = doctor
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