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Pharmacotherapeutics Final
Main drug considerations
68
Nursing
Undergraduate 3
12/11/2010

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Term
Prednisone (Deltasone)
Definition
Glucocorticoid
Term
Levothyroxine (Synthroid, Levothroid)
Definition
Synthetic T4: treats hypothyroidism
Term
Prophythiouracil (PTU)
Definition
Anithyroid Medication: interferes with hormone synthesis
Term
Methimazole (Tapazole)
Definition
Antithyroid Medication: interferes with hormone synthesis
Term
Iodine 131
Definition
Radioactive Iodine: destroys the thyroid gland
Term
Lugols Solution
Definition
Non-radioactive Iodine: slows thyroid 10-15 days before surgery
Term
Estrogen (Premarin)
Definition
Builds up uterine lining, maintains uterus, breast and vaginal function
Term
Medroxyprogesterone (Provera)
Definition
Progestin: causes thick mucous, hostile environment for sperm, starts cycle, counteract estrogen effects
Term
Contraceptives
Definition
Combo of estrogen and progestin
Term
Oxytocin (Pitocin)
Definition
Stimulates uterine contraction
Term
Testosterone Enanthate (Delatestryl)
Definition
Androgen: used for low testosterone, to increase bulk
Term
Sildenafil (Viagra) or Cialis, Levitra
Definition
Treats erectile dysfunction through vasodilation
Term
Beta Lactams
Definition
Penicillins, Cephalosporins, Monobactams, Carbapenems: inhibit bacterial wall synthesis
Term
Cephalexin (Keflex)
Definition
Type 1 Cephalosporin
Term
Cefaclor (Ceclor), Cefprozil (Cefzil)
Definition
Type 2 Cephalosporin
Term
Ceftrixone (Rocephin)
Definition
Type 3 Cephalosporin
Term
Cefepime (Maxipime)
Definition
Type 4 Cephalosporin
Term
Aztreonam (Azactam)
Definition
Monobactam
Term
Erythromycin, Clarithromycin, Azithromycin (Zithromax)
Definition
Macrolides: inhibit protein synthesis in bacteria
Term
Tetracycline (Acromycin)
Definition
Tetracycline: inhibits protein synthesis in bacteria
Term
Ciproflaxacin (Cipro)
Definition
Fluoroquinolone: interferes with DNA synthesis in bacteria
Term
Gentamycin, Garamycin
Definition
Aminoglycoside: creates fissures in outer membrane of bacteria
Term
Sulfamethoxazole (SMZ)
Definition
Sulfonamide: inhibits folic acid synthesis in bacteria
Term
Trimethoprim (TMP, Bactrim)
Definition
Sulfonamide: inhibits folic acid synthesis in bacteria
Term
Vancomycin
Definition
Inhibits cell wall synthesis in bacteria
Term
Amphotericin B
Definition
Antifungal
Term
Metronidazole (Flagyl)
Definition
Antiprotozoal
Term
Acyclovir (Zovirax)
Definition
Antiviral: interferes with viral replication
Term
Lispro Insulin (Humalog)
Definition
Rapid acting insulin
Term
Regular Insulin
Definition
Short Acting Insulin
Term
NPH Insulin (Humulin N)
Definition
Intermediate Acting Insulin
Term
Glargine Insulin (Lantus)
Definition
Long Acting Insulin
Term
Combination Insulin
Definition
Regular and Intermediate Insulin Mix (70/30)
Term
Glipizide (Glucotrol)
Definition
Sulfonylureas: increase insulin release from beta cells, decrease glucagon levels
Term
Metformin (Glucophage)
Definition
Biguanides: decrease insulin resistance (decrease GI absorption of glucose, improves liver glucose usage, decreases hepatic gluconeogenesis)
Term
Acarbose (Precose)
Definition
Alpha Glucosidase Inhibitor: inhibits carbohydrate absorption from small bowel
Term
Rosiglitazone (Avandia)
Definition
Thiazolidinediones (Glitizones): resensitizes body to insulin (banned in Europe)
Term
Glucagon
Definition
Insulin antagonist
Term
Thiazides
Definition
Diuretic
Term
Loops
Definition
Diuretics
Term
Potassium Sparing
Definition
Diuretics
Term
Captopril (Capoten)
Definition
ACE Inhibitor: causes vasodilation and diuresis
Term
Losartan (Cozaar)
Definition
Angiotensin II Blocker: causes vasodilation and diuresis
Term
Nifedipine (Procardia)
Definition
Calcium Channel Blocker used for prevention of vasoconstriction
Term
Hydralazine (Apresoline)
Definition
Vasodilator
Term
Sodium Nitroprusside (Nipride)
Definition
Vasodilator used only for hypotensive crisis!
Term
Nitroglycerin (NTG)
Definition
Coronary Vasodilator
Term
Epinephrine (Adrenaline)
Definition
Bronchodilator, Vasoconstrictor: used to treat shock
Term
Digoxin (Lanoxin)
Definition
Cardiac Glycoside: positive inotropic, negative chronotropic effect
Term
Digoxin Immune Fab
Definition
Antidote to Digoxin: binds to molecules and leads to excretion
Term
Procainamide (Pronestyl)
Definition
Type IA Antidysrhythmic: blocks Na
Term
Lidocaine (Xylocaine)
Definition
Type IB Antidysrhythmic: bocks Na
Term
Flecainide
Definition
Type IC Antidysrhythmic: blocks Na
Term
Propanolol (Inderal)
Definition
Type II Antidysrhythmic: Beta Adrenergic Blocker
Term
Amiodarone
Definition
Type III Antidysrhythmic: blocks K
Term
Verapamil (Calan)
Definition
Type IV Antidysrhythmic: blocks Ca
Term
Diltiazem (Cardizem)
Definition
Type IV Antidysrhythmic: blocks Ca
Term
Theophylline (Theolair)
Definition
Xanthine: bronchodilator
Term
Albuterol (Proventil, Ventolin)
Definition
Beta 2 Agonists: cause bronchiole and uterine relaxation
Term
Ipratropium (Atrovent)
Definition
Anticholinergic: causes decreased mucous production, may be combined with albuterol
Term
Cromolyn (Intal, Nasalcrom)
Definition
Mast Cell Stabilizer: decreases inflammatory response
Term
Montelukast (Singulair)
Definition
Leukotriene Antagonist: decreases inflammation and bronchoconstriction
Term
Corticosteroids (Inhaled)
Definition
Anti-inflammatory: prevents inflammation, decreases mucous and decreases smooth muscle contraction
Term
Diphenhydramine (Benadryl)
Definition
Antihistamine
Term
Loratadine (Claritin)
Definition
Antihistamine: 2nd generation
Term
Acetylcysteine (Mucomyst)
Definition
Mucolytic
Term
Phenylephrine
Definition
Decongestant: stimulates alpha receptors to cause constriction of nasomembranes
Term
Oxymetazoline (Afrin)
Definition
Decongestant: stimulates alpha receptors to cause constriction of nasomembranes
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