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The most important properties of an ideal drug are... |
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Definition
effectiveness, safety, & selectivity |
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There is no such thing as a ________ or ___________ drug. |
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The objective of drug therapy is to provide ___________ results with __________ harm. |
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maximum results w/ minimum harm |
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Because all patients are unique, drug therapy must be tailored to ________ ______________. |
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What is the therapeutic objective of nursing care? |
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Maximum benefit w/ minimum harm. |
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What is the goal of preadministration assessment? |
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Definition
Gather data needed for (1) evaluation of therapeutic and adverse effects, (2) identification of high-risk patients, and (3) assessment of the patient's capacity for self-care. |
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What are the 3 goals of analysis and diagnosis phase of treatment? |
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Definition
(1) judging the appropriateness of the prescribed therapy, (2) identifying potential health problems treatment might cause, (3) characterizing the patient's capacity for self-care. |
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What are the 3 goals of planning? |
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(1) defining goals, (2) establishing priorities, and (3) establishing criteria for evaluating success. |
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What are the 4 goals in the evaluation phase? |
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Definition
(1)therapeutic responses, (2)adverse reactions and interactions, (3) patient adherence, and (4)patient satisfaction with treatment. |
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Term
Pharmacokinetics consists of four basic processes, they are: |
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Definition
absorption, distribution, metabolism, and excretion. |
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Term
What is the process that determines the concentration of a drug at its sites of action, and thereby determine the intensity and time course of responses. |
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Definition
Pharmacokinetic processes |
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Term
To move around the body, drugs must cross membranes either by (3 answers) |
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Definition
(1) passing through pores, (2) undergoing transport, or (3) penetrating the membrane directly. |
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Term
P-glycoprotein is found where? Can transport a variety of drugs _____ of cells. |
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Definition
Found in the liver, kidney, placenta, intestine, and brain capillaries. ...Can transport a variety of drugs OUT of cells. |
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Term
To cross membranes, most drugs must do what? |
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Definition
dissolve directly into the lipid bilayer of the membrane. |
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Term
Lipid soluble drugs can cross membranes with difficulty or with ease? |
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Drugs that are polar or ionized cannot easily what? |
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The movement of a drug from its site of administration into the blood. |
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Absorption is enhanced by 4 methods. They are... |
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Definition
(1) High lipid solubility of the drug (2) a large surface area for absorption (3) high blood flow at the site of administration (4) rapid drug dissolution |
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Term
List 7 disadvantages of Intravenous administration. |
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Definition
high cost; difficulty; inconvenience; danger because of irreversibility; and the potential for fluid overload, infection, and embolism. |
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List two advantages of intramuscular administration. |
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Definition
suitability for insoluble drugs and suitability for depot preparations. |
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