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Pharmacology -Lehne Ch 1
Key Points from Exam 1 Respiratory, Antiinfectives, & first few chapters of Edition 8
23
Nursing
Undergraduate 3
08/28/2014

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Term
The most important properties of an ideal drug are...
Definition
effectiveness, safety, & selectivity
Term
There is no such thing as a ________ or ___________ drug.
Definition
safe or selective
Term
All drugs can cause...
Definition
side effects
Term
The objective of drug therapy is to provide ___________ results with __________ harm.
Definition
maximum results w/ minimum harm
Term
Because all patients are unique, drug therapy must be tailored to ________ ______________.
Definition
Each individual
Term
What is the therapeutic objective of nursing care?
Definition
Maximum benefit w/ minimum harm.
Term
What is the goal of preadministration assessment?
Definition
Gather data needed for (1) evaluation of therapeutic and adverse effects, (2) identification of high-risk patients, and (3) assessment of the patient's capacity for self-care.
Term
What are the 3 goals of analysis and diagnosis phase of treatment?
Definition
(1) judging the appropriateness of the prescribed therapy, (2) identifying potential health problems treatment might cause, (3) characterizing the patient's capacity for self-care.
Term
What are the 3 goals of planning?
Definition
(1) defining goals, (2) establishing priorities, and (3) establishing criteria for evaluating success.
Term
What are the 4 goals in the evaluation phase?
Definition
(1)therapeutic responses, (2)adverse reactions and interactions, (3) patient adherence, and (4)patient satisfaction with treatment.
Term
Pharmacokinetics consists of four basic processes, they are:
Definition
absorption, distribution, metabolism, and excretion.
Term
What is the process that determines the concentration of a drug at its sites of action, and thereby determine the intensity and time course of responses.
Definition
Pharmacokinetic processes
Term
To move around the body, drugs must cross membranes either by (3 answers)
Definition
(1) passing through pores, (2) undergoing transport, or (3) penetrating the membrane directly.
Term
P-glycoprotein is found where? Can transport a variety of drugs _____ of cells.
Definition
Found in the liver, kidney, placenta, intestine, and brain capillaries. ...Can transport a variety of drugs OUT of cells.
Term
To cross membranes, most drugs must do what?
Definition
dissolve directly into the lipid bilayer of the membrane.
Term
Lipid soluble drugs can cross membranes with difficulty or with ease?
Definition
With ease.
Term
Drugs that are polar or ionized cannot easily what?
Definition
cross membranes.
Term
Acidic drugs ionize in
Definition
basic (alkaline) media,
Term
Basic drugs ionize in
Definition
acidic media.
Term
Definition of absorption
Definition
The movement of a drug from its site of administration into the blood.
Term
Absorption is enhanced by 4 methods. They are...
Definition
(1) High lipid solubility of the drug (2) a large surface area for absorption (3) high blood flow at the site of administration (4) rapid drug dissolution
Term
List 7 disadvantages of Intravenous administration.
Definition
high cost; difficulty; inconvenience; danger because of irreversibility; and the potential for fluid overload, infection, and embolism.
Term
List two advantages of intramuscular administration.
Definition
suitability for insoluble drugs and suitability for depot preparations.
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