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1. Platelet Inhibitor
2. Anti- Inflammatory |
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TPA (Mechanism of action) |
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Definition
1. Binds to Fibrin-bound plasminogen at the clot site 2. converts plasminogen to plasmin 3. plasmin digest the fibrin strands at the clot site, 4. restores perfusion |
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Definition
total dose of 100 mg 1. 10 mg IV bolus in 2 minutes 2. 50 mg over 1 hour 3. 20 mg over 2nd hour 4. 20 mg over 3rd hour |
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1. 20 mg with 20 mL diluent vial 2. 50 mg with 20 mL diluent vial |
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1 mg iv push, repeat 3-5 mins, no max dose, 20 cc flush after dose. |
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potent vasoconstictor when given in high doses |
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40 unit one time dose IV/IO (in first or second dose of epi) |
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1-1.5 mg/kg to a max of 3mg/kg |
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parasympatholytic: inhibits acetylcholine at receptor sites increases HR in life threatening bradyarrhythmias |
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0.5 mg if alive 1.0 mg if dead |
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atropine (interaction problems) |
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Definition
1. digoxin 2. cholinergics 3. physostigmine 4. effects enhanced - antihistamines - procainamide - quindine - antopsychotics - benzodiazpines - antidepressants |
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reduces striated muscle contractions |
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1-2 g (2-4 mL of a 50% solution) diluted in 10 mL of D5W IV/IO over 5-20 mins |
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- Slows conduction time throught the av node
- Slows HR
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Definition
• 6 mg over 1-3 seconds - followed by 20mL flush - if no response after 1-2mins - 12 mg over 1-3 minutes - if no response, repeat 12mg • total maximum dose 30 mg |
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Definition
- Blocks sodium channels
- Blocks myocardial potassum channels
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Amiodarone (dose: adult) • Vfib/ pulseless, Vtach unresponsive to CPR, Defib, and vasopressors |
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Definition
• 300 mg IV/IO push • repeat dose 3-5 mins later: 150 mg IV/IO |
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Amiodarone (dose: adult) • recurrent life threatening Vent. Arrhythmias. |
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Definition
• Maximum cumulative dose: 2.2g/ 24 hrs • Rapid infusion: 150 mg IV/IO over 10 mins. (15 mg/min), repeat every 10 mins as needed. • Slow infusion: 360 mg IV/IO over 6 hrs (1mg/min) • maintenance dose: 540 mg IV/IO over 18 hrs (0.5mg/min) |
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Definition
- Positive Inotropic properties
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Calcium Chloride (Dose: adult) |
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Definition
• 500 mg to 1000mg • solution: 5-10 ml in 10% - for hyperkalemia and calcium channel blocker over dose. |
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Definition
- Sympathomimetic
- inotropic agent
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Definition
- Increases myocardial contractilitiy and stroke volume
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Dobutamine (dose: adults/ peds) |
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Definition
•Iv infusion at 2- 20 ug/kg/min |
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Definition
- Sympathomimetic
- Inotropic agent
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Definition
- Increases systemic vascular resistence
- dilates renal and splanchnic vasculature
- Increases myocardial contractility and stroke volume
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Dopamine (dose: adult/ped) |
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Definition
• 2-20 ug/kg/min titrated to effect |
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- 5-HT3 receptor antagoinst
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Definition
- Blocks action of serotonin (causes n/v)
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Ondansetron Hydrochloride (Zofran) Dose: adult/ Peds |
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Definition
• 4mg IV or IM (repeat every ten mins) • 0.1 mg/kg IV or IM |
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Definition
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Definition
- Calcium Channel Blocker
- Class IV antiarrhythmic
- Prolongs AV nodal refractory
- Dilates Coronary artiers and arterioles
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Definition
- 2.5 - 5.0 mg IV blous over 2 minutes
- Repeat dose: 5-10 mg may be given every 15-30 minutes
- maximum dose: 20 mg
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