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Methotrexate in eukaryotes
Trimethoprim in prokaryotes |
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| Inhibits the bacterial topoisomerase in DNA replication |
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Fluoroquinolone
Can increase the risk of tendon rupture |
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| Inhibits the synthesis of folic acid within bacteria. Specifically inhibits dihydropterate synthetase |
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Sulfonamides;
Sulfamethoxazole, sulfisoxazole
Sulfadiazine |
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| What drugs cause sulfa allergies? |
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Colchicine
Probenecid
Acetazolamide
Thiazide diuretics
Furosemide
Most Sulfas in general |
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