Term
| Antipsychotics are also known as _______? |
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Definition
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Term
| Name the two groups of Neuroleptics? |
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Definition
| Conventional and Atypical (misc) |
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Term
| What are the uses of Antipsychotics? |
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Definition
| Psychotic disorders, Tourett's, bipolar, mania, emesis suppression, and Huntington's chorea |
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Term
1. What kind of systoms are associated with antipsychotics?
2. Which drugs treat what? (conventional and atypical) |
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Definition
1. Postivite and negative
2. Conventional treat postitive sxs and atypical treats both |
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Term
| What are the two conventional drugs? |
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Definition
| Chlorpromazine and Haldoperidol |
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Term
| Which of the two has a high potency and low potency between Chlorpomazine and Haldoperidol |
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Definition
Low- Chlorpromazine
High- Haldoperidol |
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Term
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Definition
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Term
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Definition
| When you are frozen in one postiton (like freeze tag) nnd to get to the Dr. |
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Term
| What drug would you associate with the atypicals? |
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Definition
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Term
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Definition
Blocks DA and 5-HT (serotonin)
Also blocks histamine, ACh and norepinephrine |
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Term
| What is Clozapine used for? |
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Definition
| Tx of schizophrenia, levodopa induced psychosis. |
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Term
| What are some side effects of Clozapine? |
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Definition
| Sedation, hypotension, weight gain, anticholinergic and neuroendocrine effects |
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Term
| What would you have to watch out for when a patient is on Clozapine? |
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Definition
Possible diabetes, weight gain (30+ lbs)
Increases sz
Myocarditis |
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Term
| Why is there limited use of Clozapine? |
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Definition
Because of Agranulocytosis resulting in sepsis (1:5000)
NND weekly WCB (lab) |
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Term
| How long does it take for antidepressants to work and why? |
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Definition
| 3-4 wks. because of adaptation and long half life |
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Term
| What are some treatments for depression? (3) |
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Definition
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Term
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Definition
| Effective treatment for severe depression with risk of suicide |
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Term
| What are the four groups of antidepressants? |
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Definition
| tricyclics, SSRI's, MAOI, Atypicals |
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Term
| Side effects of Amitriptyline |
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Definition
| dry mouth, sedation, postural hypotension, diaphoresis |
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Term
| What does Amitriptyline do? |
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Definition
| Block the re-uptake of NE and serotonin (5-HT) |
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Term
| What is Amitriptyline used for treatment of? |
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Definition
| Depression, bipolar disorder and pain (headaches and nerve pain) |
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Term
| When is the best time to give Amitriptyline? |
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Definition
| At night because it causes sedation |
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Term
| If a patient becomes toxic with tricyclics what is the drug used to reverse it? |
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Definition
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Term
| Why are tricyclics not presibed much? |
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Definition
| Because of potential for toxicity and overdose. Can increase sz |
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Term
| What is the prototype for the SSRI's? |
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Definition
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Term
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Definition
| Major depression, OCD, bulimia, PMS Dysphoric disorder |
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Term
| What are the unlabeled uses of Fluoxetine? |
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Definition
| Panic attacks, PTSD, social phobia, alcoholism, ADHD, bipolar, migraine, Tourette's and obesity |
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Term
| What are SSRI's perfered over TCA's and MAOI's? |
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Definition
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Term
| What are the side effects of Prozac? |
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Definition
| Sexual dysfunction, nausea, headache, nervousness, insomina, anxiety and weight gain |
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Term
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Definition
| CNS stimulation, hypotension |
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Term
| What happens if you mix Tyramine and a MAOI? |
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Definition
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Term
| What kind of drug is Bupropion and what does it do? |
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Definition
Is an antidepressant (Atypical drug)
Believed to block DA uptake,
Similar to an amphetamine so increases energy and supresses appetite |
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Term
| What are two good reasons that Bupropin (Wellbutrin) is perferred over antidepressants? |
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Definition
| Does not cause weight gain or sexual dysfunction may increase sex drive |
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Term
| What are some side effects of Bupropion? |
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Definition
| agaitation, headache, dry mouth, consntipatoin, wt loss, gi upset, dizziness, tremor, blurred vision, insomnia and tachycardia |
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Term
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Definition
| With Mood stabilizers, antidepressants, atypical antipsychotics and ECT |
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Term
| What are some drugs used to treat Bipolar? |
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Definition
| Antidepressants: Wellbutrin, Effexor, Prozac and Zoloft |
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Term
| How is Lithuium excreted? |
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Definition
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Term
What is the goal of maintance (range) with Lithium?
What amount are you not to go over? |
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Definition
0.4 to 1.0 mEq/L
1.5 .Eq/L |
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Term
| What kind of half life does Lithium have and how safe is it? |
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Definition
| Has short half life and narrow range of safety. Take it several times a day. |
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Term
| What are the adverse effects of Lithium? |
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Definition
| Fine hand tremor, gi upset, thirst, muscle weakness, polyuria, confusion and headhache. |
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Term
| What are the drug interactions of Lithium? |
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Definition
| Diuretics, NSAIDS and anticholinergerics |
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Term
| What do sedative-hypnotics treat? |
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Definition
| insomnia, anxiety, sz disorders, muscle spasms, panic disorders and alcohol withdrawal |
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Term
True/Flase
With Sedative-hypnotics the response is dose related so SE's increase with dosage |
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Definition
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Term
| Side effects of sedative-hypnotics? |
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Definition
| CNS depression, anterograde amnesia, paradoxical effects, respiratory depression, abuse |
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Term
| What are two issues associated with sedative-hypnotics? |
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Definition
| tolerance and physical dependence |
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Term
| What are the drug of choice for panic disorders? |
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Definition
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Term
True/False
All CNS stimulants do not cause convulsions |
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Definition
False
All CNS stimulants CAN CAUSE convulsions |
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Term
| How do amphetamines work? |
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Definition
| Promote NE and DA release and inhibiting re-uptake (stay in gap longer) |
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Term
| What are some side effects of CNS stimulants? |
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Definition
insomnia, restlessnes, wt loss, appetite supression, HTN, dysrhythmias
Phychosis |
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Term
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Definition
| ADHD, narcolepsy and obesity |
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Term
| Name one main thing you have to monitor with a child taking Methylphenidate. |
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Definition
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Term
| Name some uses for Caffeine |
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Definition
| CNS stimulant, bronchodilatoin, peripheral vasodilator, diuretic but CNS vasoconstictor. |
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Term
| Caffeine can be used to treat what? |
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Definition
| apnea in babies and to increase wakefulness |
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Term
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Definition
| nervousness, tremors, insomnia, palpitations, gi upset, headache |
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Term
| How much alcohol can you body metabolize in one hour? |
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Definition
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Term
| What is the name of the drug that makes you puke if you injest alcohol? |
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Definition
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Term
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Definition
| Drug use that is inconsistent with medical or social norms. |
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Term
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Definition
| A state in which a particular drug dose elicits a smaller response than it formally did. |
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Term
What is cross tolerance?
Give example |
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Definition
A state in which tolerance to one drug confers tolerance to another drug
For example, tolerance to herion confers tolerance to other opioids: morphine |
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Term
| What is psychologic dependence? |
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Definition
| An intense subjective need for a particular psychoactive drug |
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Term
| What is physical dependance? |
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Definition
| A state in which an abstinence syndrome will occur if drug use is discontinued |
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Term
What is cross dependance?
Give example |
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Definition
The ability of one drug to support psysical dependence on another drug.
For example, Herion users take methadone |
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Term
What is withdrawal syndrome?
Give example |
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Definition
a group of signs and symptoms that occur in physically dependent individuals when they discontinue drug use.
For example, discontinuation of a CNS depressant can cause CNS excitation |
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Term
| What are some side effects of nicotine? |
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Definition
| CV vasoconstriction, HTN, dysrhythmias, increase gi acid, N and V, CNS stimulant |
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Term
| Smoking Nicotine can be treated with? |
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Definition
| Psychotherapy, support groups, replacement therapy with gum, pills or patches, antidepressants, Clonidine |
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Term
1. How many days should MAOIs be withdrawn before starting Fluoxetine?
2. When Fluoxetine is discontinued how much time should elapse before giving an MAOI? |
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Definition
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