Block uptake of circulating andro

Prostitutes dying wish was to take her boobies to a leuau to stop guys w/no balls from making rounds, to let her gonads go!

Irrev prostate cancer, gynecomastia, Leuprolide, anti-androgen, bilateral orchiectomy and LHRH analog, stop circulating, and release of GNRH. 

Flutes buy guys time when making rounds.

Anti-andro, decrease circulating to buy time.

A nasty smell.

Aromatase inhib.

Exemestane

Fulvestrant

Exams smell bad to women wearing full vests.

Aromatase inhib, est receptor block b/c have no estradiol to bind to receptors. (Fulvest is also anti-est)

Hammocks are bad for post-menopausal competitive depressed women.

Anti-est, compete for est receptor, drives Liver metabolism (CYP2D6) to active, bad for x-depression drugs (Paxl, prazac) b/c they need the enzymes too.

Loose temper, loose hair and yell "FU!!!"

Less TMP via inhib thymidylate synthetase.  Hair loss like cyclophos.

Flute players on extreme steroids lay in hammocks @ leuau wearing nasty vests.

Flutamide, Exemestane, Corticoids, Tamoxifen, Leuprolide, Anastrozole, Fulvestrant.

Bloody alky peed on a solid plate S/F chocolate chip cookies.

IV in, like alkylating agents, renal tox, solid tumors, platinum containing, manitol diuresis and hydration, like chocolate chip cookie discovery (from lab to XB).

Foley catheters rescue meth heads

In periph, give Folinic acid and can make tetra w/out dyhydro enzyme, in periphery w/methotrexate.

Binds DNA to block synth.

Bald Adrian stalks Deena, latches on and stops her from running, gives her a heart attack, and makes her keep a low profile.  Too bad because its common to see her running as shes a solid runner.

Hair loss, Adriamycin, binds DNA to stop RNA, cardio tox, keeps blood levesl below a certain amount. Common chemo, solid tumors.

Meet my solid Alky.

Alkylating, solid tumors.

Adrian blew my acting gig, sad cuz I'm such a mighty natural.

Adriamycin (doxorubicin), Bleomycin, Actinomycin D, Mitomycin, Natural Ab's.

Strand breaks in DNA

Blowing solidly wont break Deena.

Pulmonary fibrosis, solid tumors, DNA breaks.

Inhibit RNA synthesis

Runners naturally act like don't have stress fractures, and can run when very sick.

RNA synth, non-cycle active, BM supp, Very toxic, immuno sup (lots).

Inhibit dihydrofolate reductase

Kids on meth sniff watery glue.

DON'T GIVE TO RENAL ISSUES!!!!  sniff to bring into cell, inhib dihydrofolate reductase (can't become tetra), conj to Glu to trap inside cells.

Metaphase arrest

I met Vin, he blasted my solid cycle and moved on to  cute brainy Christine because shes a natural.

Metaphase stop, Vins's, Blast: myelosupp, solid tumors, cycle active, cristine: CNS, acute leuk.  Natual Product

Stabilize microtubles.

Solid tax on all natural bike tubes.

Solid tumor, taxol, natural product, cycle active microtubles less pliable so can't pull apart.

INhibit DNA synthesis, alter DNA template activity.

Denas wedding ring altered her temporary (non-active) status.

DNA synth, GEM, alteres temp activity, non-cycle active, solid tumor.

Metabolized to flurouracil, compete w/dihydro dehydrog to keep more flurouracil in body.

Keep yelling FU! at pros who use tees or stay in water!!

Keeps 5-FU high b/c competes for dyhydropyrimidine dehydrogenase.  Prodrug metabolized to flurouracil.

Inhibit IMP and AMP/GMP, also change structure and function.

Thio: incorporate into DNA to alter structure and function.

Captain has pure IMPotence.

Blocks IMP form, and other steps to purine synthesis.

Thioguanine does same for GMP.  (alter structure and function) w/both = complementary inhib.

6-mer blocks IMP and it's change to AMP and GMP = sequential inhib.

Alkylating Agent

Booze for my alkys.

Myelosupp, alkylating agent.

Pho long horn rams @ BU are fat, ride bus, b/c got BUI for being non-functional.

Cyclophosp (hair loss, rapid, metabolic activation and normal liver), Chlorambucil (least toxic, for chronic), BCNU (IV, Lipid, CNS), Busulfate (myelosup), non-cycle active, modify pre-formed (change structure and function), alkylating agents.