Term
| Drugs which increase GABA activity/efficacy can cause |
|
Definition
|
|
Term
| Decreasing GABA activity will produce |
|
Definition
|
|
Term
| Which of the following have a direct effect to increase the flow of chloride ions through the Cl- ionophore? |
|
Definition
|
|
Term
| Which of the following mechanisms is associated with Benzodiazepine activity? |
|
Definition
| increased frequency of Cl- channel openings |
|
|
Term
| Which of the following mechanisms is associated with Barbiturate activity? |
|
Definition
| increased duration of Cl- channel openings |
|
|
Term
| Benzodiazepines are useful for treating |
|
Definition
anxiety
insomnia
epilepsy |
|
|
Term
| Which of the following is most closely associated with the etiology of Parkinson's Disease? |
|
Definition
| neurodegeneration in the substantia nigra |
|
|
Term
| Which of the following effects are associated with benzodiazepine activity: |
|
Definition
| decreased recall (memory loss) |
|
|
Term
| Conventional antipsychotics produce drowsiness due to: |
|
Definition
|
|
Term
| Which of the following symptoms are associated with Parkinsons disease? |
|
Definition
tremor
increased muscle tone
bradykinesia |
|
|
Term
| Which of the following is not a symptom typical of schizophrenia? |
|
Definition
|
|
Term
| Loss of activity of which of the following is associated with narcolepsy? |
|
Definition
|
|
Term
| Which of the following symptoms are associated with Parkinsons disease? |
|
Definition
|
|
Term
| Which of the following are true for Parkinsons disease? |
|
Definition
| increased susceptibility to infection |
|
|
Term
| Atypical antipsychotics differ from the older, conventional antipsychotics in that they show less: |
|
Definition
| parkinson-like side effects |
|
|
Term
| Which of the following is a benzodiazepine useful for treating insomnia? |
|
Definition
|
|
Term
| Which of the following is best in treating generalized anxiety disorder (GAD)? |
|
Definition
|
|
Term
| Atypical antipsychotics differ from the older, typical antipsychotics in that they show less: |
|
Definition
|
|
Term
| Ethanol potentiates the effects of benzodiazepines because: |
|
Definition
| they both increase Cl- ion influx |
|
|
Term
| Positive symptoms of schizophrenia include: |
|
Definition
|
|
Term
| Primarily useful in younger Parkinson's patients whose major symptom is tremor would be: |
|
Definition
|
|
Term
| The primary receptor for Glutamate is: |
|
Definition
|
|
Term
| GABA, Adenosine, and DA are |
|
Definition
| inhibitory neurotransmitters in the CNS |
|
|
Term
|
Definition
| adenosine A2 receptor blocker |
|
|
Term
| A depressed person who does not meet all the criteria for major depression, but remains somewhat depressed for a long period of time is said to have: |
|
Definition
|
|
Term
| Which of the following is not true? |
|
Definition
| Depression is rarely seen in the elderly (>65) |
|
|
Term
| Major depression is best associated with: |
|
Definition
|
|
Term
| Patients taking atypical antipsychotic drugs are at increased risk of developing |
|
Definition
|
|
Term
| Which of the following is true for Ghrelin? |
|
Definition
promotes growth hormone release
secreted by P/D1 cells in fundus of stomach
increases appetite by stimulating NP-Y secretion |
|
|
Term
| Which of the following is not involved in promoting appetitie (stimulates eating) |
|
Definition
|
|
Term
| Loss of activity of which of the following is most likely to be associated with insomnia? |
|
Definition
|
|
Term
| Which of the following is most likely to be affected by substance P? |
|
Definition
mood
pain perception
nausea and vomiting |
|
|
Term
| Which of the following contributes to Leptins' appetitie-suppresion acitivity? |
|
Definition
| decreases NP-Y seccretion |
|
|
Term
| Which of the following is true for Ghrelin? |
|
Definition
| ir promotes learning and memory |
|
|
Term
|
Definition
| a major inhibitory neurotransmitter in the CNS |
|
|
Term
|
Definition
| drugs that enhance GABA activity |
|
|
Term
| Absence of leptin synthesis results in: |
|
Definition
|
|
Term
| An unpleasant emotional state of worry without a readily appparent cause is: |
|
Definition
|
|
Term
|
Definition
made up of multiple subnits
associated with a Cl- ionophore
located in neuronal membranes in the CNS |
|
|
Term
| Increasing GABA activity will produce: |
|
Definition
|
|
Term
| Benzodiazepines are useful for treating: |
|
Definition
anxiety
insomnia
epilepsy |
|
|
Term
| Which of the following have a direct effect to increase the flow of chloride ions through the Cl- ionophore? |
|
Definition
|
|
Term
| Which of the following mechanisms is associated with allopregnanolone activity? |
|
Definition
| increased duration of Cl- channel openings |
|
|
Term
| Which of the following is least likely to be helped if treated using a benzodiazepine? |
|
Definition
| OCD (obsessive compulsive disorder) |
|
|
Term
| A Glycine receptor antagonist is most likely to be? |
|
Definition
|
|
Term
| A GABA receptor antagonist (blocker) is most likely to be? |
|
Definition
none of the above!!!!
antidepressant, antoconvulsant, antianxiety, antipsychotic |
|
|
Term
| An excitatory CNS neurotransmitter is: |
|
Definition
|
|
Term
| Which of the following is not associated with a Cl- ionophore? |
|
Definition
|
|
Term
| Benzodiazepine receptor activation is assoicated with: |
|
Definition
| enhanced GABA receptor activity |
|
|
Term
|
Definition
| associated with a Cl- ionophore |
|
|
Term
| Which of the following mechanisms is associated with the antiepileptic activity of Phenytoin (Dilantin)? |
|
Definition
| increased duration of Na+ channel inactivation |
|
|
Term
| Glycine receptor activation is associated with: |
|
Definition
| increased Glutamate activity |
|
|
Term
| A drug which blocks the acitivity of GABA-transaminase will cause: |
|
Definition
|
|
Term
| A drug which blocks reuptake of NE or 5-HT (serotonin) may be useful as: |
|
Definition
|
|
Term
| The primary use for benzodiazepines is for treating: |
|
Definition
|
|
Term
| Which of the following is the antidepressant Bupropion also marketed for? |
|
Definition
|
|
Term
| Which of the following is Buspirone most useful for? |
|
Definition
|
|
Term
| Which of the following statements is true concerning drug action in the CNS? |
|
Definition
| most psychoactive drugs cause multiple changes in neurotransmitter activity |
|
|
Term
| Which of the following is a N-type calcium channel blocker? |
|
Definition
|
|
Term
| A norepinephrine reuptake blocker is most likely to be? |
|
Definition
|
|
Term
| An MAO-A inhibitor is most likely to be? |
|
Definition
|
|
Term
|
Definition
| neurotransmitter in afferent pain pathway |
|
|
Term
| Which of the following best describes the mechanism for Buspirone (Buspar)? |
|
Definition
|
|
Term
| Patients with which of the following are most likely to attempt suicide: |
|
Definition
|
|
Term
| Which of the following is a SSRI most likely to be associated with SSRI discontinuation syndrome? |
|
Definition
|
|
Term
| Which of the following SSRI least likely to be associated with SSRI discontinuation syndrome? |
|
Definition
|
|
Term
| A COMT inhibitor would be a useful adjunctive agent in treating: |
|
Definition
|
|
Term
| Which of the following is least likely to be an action of a Dopamine agonist? |
|
Definition
NONE OF THE ABOVE!!! (they are all actions)
hallucinations
convulsions
nausea and vomiting |
|
|
Term
| An MAO-B inhibitor is most likely to be? |
|
Definition
|
|
Term
| Primarily useful in younger Parkinson's patients whose major symptom is tremor would be: |
|
Definition
|
|
Term
| The loss of dopaminergic input to the striatum results in all the following except: |
|
Definition
| increased prolactin secretion |
|
|
Term
| Parkinson's symptomology begins to show up when nigrostriatal tract nerve loss has reached: |
|
Definition
|
|
Term
| Which of the following is most likely to develop due to the death of CNS dopaminergic neurons? |
|
Definition
|
|
Term
| Stalevo is a combination drug that contains Levodopa, Carbidopa, and the COMT inhibitor: |
|
Definition
|
|
Term
| Tremor in an elderly person with no other Parkinson disease (PD) features is most likely: |
|
Definition
|
|
Term
| A side effect of dopamine receptor agonists may be: |
|
Definition
|
|
Term
| Anti-Parkinson's medications provide for: |
|
Definition
| good symptomatic control for 4-6 years |
|
|
Term
| Which of the following is associated with slowing the progression of disability from Parkinson's disease? |
|
Definition
|
|
Term
| Which of the following is associated with increased risk of developing Parkinson's disease? |
|
Definition
exposure to certain pesticides
exposure to arc-welding fumes
head injuries |
|
|
Term
| A patient with schizophrenia that is confused and is laughing for no reason or is fearful for no reason is exhibiting: |
|
Definition
|
|
Term
| A patient with schizophrenia that demonstrates social withdrawal and poor personal hygiene is exhibiting: |
|
Definition
|
|
Term
| Which of the following is most closely associated with the etiology of Schizophrenia? |
|
Definition
|
|
Term
| Patients with schizophrenia are at increased risk for: |
|
Definition
suicide
depression
substance abuse |
|
|
Term
| A dopamine receptor antagonist (blocker) is most likely to be? |
|
Definition
|
|
Term
| A dopamine receptor agonist is most likely to be? |
|
Definition
|
|
Term
| Which of the following is not a result of blocking D2 receptors? |
|
Definition
| parkinson-like movement disorder |
|
|
Term
| All patients atypical antipsychotic drugs are at increased risk of developing: |
|
Definition
|
|
Term
| Symbyax is a combination drug that contains the antipsychotic and antidepressant: |
|
Definition
|
|
Term
| True for conventional antipsychotics: |
|
Definition
| primarily D2 receptor blockers |
|
|
Term
| True for atypical antipsychotics: |
|
Definition
| primarily 5HT2a receptor blockers |
|
|
Term
| The antipsychotic drug with the greatest efficacy in terms of broad-spectrum patient improvement is: |
|
Definition
|
|
Term
| A non-benzodiazepine which is useful as a hypnotic is: |
|
Definition
|
|
Term
| A benzodiasepine which is useful as an antiepileptic is: |
|
Definition
|
|
Term
| neurotransmitter in afferent pain pathway |
|
Definition
|
|
Term
| dopamine precursor, for DA replacement therapy |
|
Definition
|
|
Term
| peripheral decarboxylase inhibitor |
|
Definition
|
|
Term
| drug that increases neural DA release |
|
Definition
|
|
Term
| neurosteroid enhances GABA activity |
|
Definition
|
|
Term
| Cannabinoid receptor (CB1) agonist found in chocolate |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| 2-arachadonyl glycerol (2-AG) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| inhibit GABA-transaminase |
|
Definition
|
|
Term
| increase GABA release from nerve terminals |
|
Definition
|
|
Term
| BZ which enhances GABA efficiency at opening Cl- ionophore |
|
Definition
|
|
Term
| enhances GABA action by holding Cl- ionophore open |
|
Definition
|
|
Term
| non-benzodiazepine BZ receptor agonist |
|
Definition
|
|
Term
| benzodiazepine receptor antagonist |
|
Definition
|
|
Term
| glycine receptor antagonist |
|
Definition
|
|
Term
|
Definition
|
|
Term
| prolong Na+ channel inactivation |
|
Definition
|
|
Term
| T-type Ca++ channel blocker |
|
Definition
|
|
Term
| patients suffer from their problem and want be rid of it |
|
Definition
|
|
Term
| patients develop this after witnessing a traumatic event |
|
Definition
|
|
Term
| patients are preoccupied with orderliness and perfectionism |
|
Definition
|
|
Term
| patients are unaware or unconvinced that they have a problem |
|
Definition
|
|
Term
| patients are prone to periodic uncued panic attacks |
|
Definition
|
|
Term
| patients are distressed at spending so much time carrying out certain tasks or rituals |
|
Definition
|
|
