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Pharmacology
Exam 3 2012
117
Pharmacology
Undergraduate 3
03/01/2012

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Cards

Term
Epinephrine stimulates this type of receptor to produce increased heart rate:
Definition
ß1-receptor
Term
Which of these organs helps to maintain a high blood pressure during a fight/flight situation?
Definition
Heart
Term
The uptake 1 process at the sympathetic synapse:
Definition
"recycles" norepinephrine
Term
Phenylephrine (Neo-synephrine):
Definition
causes a vasoconstriction in the nasal passages
Term
Which of the following enzymes is responsible for terminating the effects of acetylcholine at the parasympathetic nerve endings?
Definition
acetylcholinesterase
Term
Both sympathetic and parasympathetic ganglia during neurotransmission is:
Definition
nicotinic, cholinergic
Term
Preganglionic parasympathetic nervew originate from the:
Definition
sacral spinal cord
Term
Pre- and postganglionic nerves of the parasympathetic nervous system meet:
Definition
close to the innervated tissue
Term
Which of the following agents will inhibit acetylcholinesterases to indirectly cause muscarinic receptor stimulation?
Definition
VX gas
Term
Which of the following agents is least prone to acetylcholinesterase metabolism?
Definition
bethanechol
Term
An antidote for Sarin gas poisoning would be?
Definition
Pralidoxime (2-PAM)
Term
A drug used to treat premature labor would be:
Definition
terbutaline
Term
Albuterol (ventolin may be used to treat sudden asthma attacks by:
Definition
Its ability to activate ß-adrenergic receptors on bronchial passages
Term
Which of these agents is useful for treating nasal congestion?
Definition
Pseudophedrine
Term
Which of the following receptors causes decreased GI tract motility?
Definition
ß-adrenergic 
Term
Which of the following drugs is not a muscarinic receptor antagonist?
Definition
carbachol
Term
Which of the following agents is not a ß-adrenergic receptor agonist?
Definition
methacholine
Term
Which of the following is not an effect of the parasympathetic nervous system?
Definition
pupilary dilation
Term
Which of the following agents blocks the uptake 1 process of sympathetic nerves?
Definition
cocaine
Term
Which of the following may be an effect of nerve gas (VX) poisioning?
Definition
diarrhea
Term
Which of the following drugs would be a selective agonist for α-adrenergic receptors?
Definition
phenylephrine
Term
A patient is rushed into the emergency department after being stung by a wasp and showing signs of anaphylaxis. Which of these drugs would be most useful to treat the symptoms of anaphylaxis?
Definition
epinephrine
Term
monoamine oxidase
Definition
metabolizes norepinephrine
Term
parasympathetic ganglia
Definition
nicotine receptor
Term
ß-adrenergic receptor
Definition
glucose release
Term
parasympathetic nerves
Definition
long pre-ganglionic, short post-ganglionic
Term
sympathetic nerves
Definition
thoracic/lumbar portion of spinal cord
Term
muscarinic receptor antagonist
Definition
atropine
Term
sympathetic neurotransmitter
Definition
norepinephrine
Term
hormone
Definition
epinephrine
Term
NaCl transporter inhibitor
Definition
hydrochlorothiazide
Term
aldosterone receptor antagonist
Definition
spironolactone
Term
carbonic anhydrase inhibitor
Definition
acetazolimide
Term
Na/K/Cl symport inhibitor
Definition
furosemide
Term
vasopressin receptor antagonist
Definition
conivaptan
Term
α1 selective antagonist
Definition
prazosin
Term
non-selective β antagonist
Definition
propranolol
Term
non-selective β and α1 blocker
Definition
carvedilol
Term
α2 selective agonst
Definition
clonidine
Term
β1selective agonist
Definition
dobutamine
Term
β1 selective antagonist
Definition
metoprolol
Term
renin inhibitor
Definition
aliskiren
Term
block cardiac Ca channels
Definition
verapamil
Term
blocks cardiac and vascular calcium channels
Definition
diltiazem
Term
blocks vascular calcium channel
Definition
nifedipine
Term
promotes venous dilation
Definition
nitroglycerin
Term
AT1 receptor antagonist
Definition
candesartan
Term
K+ channel opener
Definition
minoxidil
Term
ACE inhibitor
Definition
captopril
Term
Endothelin receptor antagonist
Definition
bosentan
Term
Which of the following would be most useful to reduce elevated intracranial pressure?
Definition
mannitol
Term
First-line therapy for most CHF patients will be:
Definition
ACE inhibitor
Term
First-line therapy for patients with essential hypertension would be:
Definition
thiazide diuretic
Term
Which of the following dominate the clinical picture with left-sided heart failure?
Definition
pulmonary edema
Term
Which of the following symptoms is most likely to be associated with right-sided heart failure?
Definition
peripheral edema
Term
Which of the following is recommended first for a patient with blood pressure of 138/88?
Definition
lifestyle changes
Term
Which of the following is most useful for treating pulmonary hypertension?
Definition
bosentan
Term
Which of the following are the most efficacious diuretics currently available?
Definition
loop diuretics
Term
Which of the following can be used to inhibit ADH secretion?
Definition
H2O
Term
Which of the following are alpha-1a receptor blockers useful in treating?
Definition
benign prostatic hyperplasia (BPH)
Term
At any given time, most of the blood in the body will be located in the:
Definition
veins
Term
A drug which causes arterial dilation will likely also be associated with:
Definition
reflex tachycardia
Term
Which of the following might be best for acute hypertensive emergency?
Definition
nitrodilator
Term
The blood in the circulatory system is moving at its slowest rate in the...
Definition
capillaries
Term
The most common and troublesome side effects in patients taking an ACE-inhibitor is:
Definition
dry cough
Term
Which of the following is most likely to be useful for Prinzmetal's angina?
Definition
nitrodilator
Term
The parasympathetic nervous system is a division of:
Definition
peripheral nervous system
Term
parasympathetic nerves that supply the heart cause:
Definition
no change in cardiac function
Term
the parasympathetic nerves originate from the:
Definition

-sacral portion of the spinal cord

-brain stem

Term
the neurotransmitter that allows for transmission of nerve activity in the parasympathetic ganglia is:
Definition
acetylcholine
Term
Which of the following would result in you if a hungry bear wandered onto your campsite:
Definition
increased pupil diameter
Term
Which of the following would be a consequence of the Uptake 1 process into the nerve ending?
Definition
metabolism by monoamine oxidase
Term
Which of the following agents is able to block the Uptake 1 process in sympathetic neurons?
Definition
cocaine
Term
The enzyme responsible for metabolism of acetylcholine is:
Definition
acetycholinesterase
Term
An example of an indirectly acting parasympathomimetic agent would be:
Definition
acetycholine
Term
Responsible for the control of norepinephrine concentrations in the synaptic space:
Definition
uptake 1 pump
Term
Methacholine may be described as a:
Definition
muscarinic receptor antagonist
Term
Which of the following agents is not a β-adrenergic receptor agonist?
Definition
norepinephrine
Term
which of the following therapeutic uses would be appropriate for bethanechol?
Definition
for urinary incontinence
Term
which of the following drugs is not a muscarinic receptor antagonist?
Definition
bethanechol
Term
which of the following drugs is most rapidly metabolized by cholinesterases?
Definition
acetylcholine
Term
which of the following is used for the treatment of acute asthamatic attacks?
Definition
albuterol
Term
Which of the following physiological effects may be seen with a direct-acting sympathomimetic agent e.g. epinephrine?
Definition
bronchodilation
Term
what receptors are activated to treat nasal congestion?
Definition
α-adrenergic
Term
Which receptor type is involved in increasing blood pressure during a fight or flight situation?
Definition
β1-adrenergic
Term
Which of the following agents would be used to cause uterine smooth muscle relaxation during premature labor?
Definition
terbutaline
Term
the pump of the circulatory system is/are the
Definition
heart
Term
when resistance decreases and cardiac output remains the same, what else will happen?
Definition
blood pressure will decrease
Term
If diuretics cause a decrease in blood volume, how/why would this affect blood pressure
Definition
decreased blood pressure due to decreased venous return and cardiac output
Term
acetylcholine causes decreased heart rate via
Definition
muscarinic receptors
Term
what catalyzes the formation of angiotensin I?
Definition
renin
Term
ACE inhibitors will cause both:
Definition
vasodilation and diuresis
Term
pain in the chest due to ischemia is called
Definition
angina pectoris
Term
Which of the following blood pressures indicates that the patient has stage 1 hypertension?
Definition
145/95
Term
Thiazide diuretics block the
Definition
Na+/Cl- transporter
Term
The Na+/Cl- transporter is located in the
Definition
distal tubule
Term
osmotic diuretic
Definition
mannitol
Term
PDE-3 inhibitor
Definition
milrinone
Term
inhibit cardiac Na/K ATPase
Definition
digoxin
Term
Which of the following is most likely to be usefu for Prinzmetal's angina?
Definition
nitrodilator
Term
Which of the following is most likely to be associated with reflex tachycardia?
Definition
nifedipine
Term
Which of the following is most useful for treating pulmonary hypertension?
Definition
bosentan
Term
Which of the following are the most efficacious diuretics currently available?
Definition
loop diuretics
Term
Which of the following can be used to inhibit ADH secretion?
Definition
H2O
Term
Which of the following are alpha-1a receptor blockers useful in treating?
Definition
benign prosthetic hyperplasia (BPH)
Term
a drug which causes arterial dilation will likely also be associated with:
Definition
reflex tachycardia
Term
Which of the following might be best for acute hypertensive emergency?
Definition
nitrodilator
Term
The most common and troublesome side effects in patients taking an ACE-inhibitor is:
Definition
dry cough
Term
The actions of epinephrine vary most widely from norepinephrine in which of the following?
Definition
significantly greater beta-2 effect
Term
Which of the following can be used to alkalinize the urine?
Definition
acetazolamide
Term
Which of the following can be used to treat excessive potassium loss due to chronic diuretic therapy?
Definition
amiloride
Term
Which of the following would be most useful to reduce elevated intracranial pressure?
Definition
mannitol
Term
First-line therapy for msot CHF patients will be:
Definition
ACE inhibitor
Term
First-line therapy for patients with essential hypertension would be:
Definition
thiazide diuretic
Term
Which of the following dominate the clinical picture with left-sided heart failure?
Definition
pulmonary edema
Term
Which of the following symptoms is most likely to be associated with right-sided heart failure?
Definition
perpheral edema
Term
Which of the following is recommended for a patient with blood pressure of 136/88?
Definition
lifestyle changes
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