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Anticonvulsant for Bipolar disorder, neuropathic pain. Sodium channel blocker. |
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Anticonvulsant for Bipolar disorder. Calcium channel blocker. Used for fibromyalgia. |
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For Bipolar Sodium channel blocker, anticonvulsant. Inhibiting sodium channels doesn't allow sodium ions to promote electrical flow down axon. Inhibits neurons.Inhibits flare of mania. Side effects: sedative, cognitive effects |
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Neuropathic pain, bipolar, anticonvulsant, depressive episodes Sodium channel blocker |
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Sodium channel blocker Anticonvulsant for seizures, trigeminal neuralgia |
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Antipsychotic. tranquilizer. Inhibit dopamine pathways. SIde Effects: less Parkinson's side effects than Haldol |
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Old generation antipsychotic Inhibit dopamine pathways. Side effects: Parkinson like. Tardive diskinesia- irreversible. |
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Thiazide type diuretic For HTN. Impairs sodium, chloride reabsorption in distal tubule. Low ceiling, long lasting Side effects: Hypokalemia |
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Loop Diuretic. Blocks sodium, chloride channels in Loop of Henle. High ceiling. For HT failure, edema, less common for HTN |
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ACE inhibitor (Angiotensin Converting Enzyme)Decreases effects of Angiotensin 2 which raises bp. For HTN Also prolongs life in HT failure by prevent release of neurotransmitters that are toxic to HT. Side effect: dry cough |
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ARB (angiotensin receptor blocker) Decrease effect of A2 by blocking the receptors. For HTN. Also improves survival rate with HT failure. |
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Selective Beta blocker. Block beta 1 adrenergic receptors. Decreases contractility of HT to decrease bp. Treats HBP Side effects: erectile dysfunction, bradycardia, fatigue, exercise intolerance |
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Beta blocker. Nonselective. Rarely used for HTN. Mostly for migraines, stage fright. |
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Calcium channel blocker for HTN. |
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Cardiac Glycoside. For HT failure. Makes HT pump faster, increases contractility of HT, inhibits sodium potassium pump in HT. Many side effects (seeing yellow) |
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For Diabetes. Alpha glucosidase inhibitors. Inhibit enzyme that breaks dwon starch into simple sugars. Side effects: flatulence. |
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Diabetes. A Biguinide. Sensitizes LV to insulin. Controls fasting glucose. Leads to weight loss, reduces HT attacks. |
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Diabetes. A TZD Sensitizes muscles to insulin. Instructs them to take up glucose more effectively. Side effects: Fluid Retention, HT failure |
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DIabetes: Insulin Secretagogue. Tells pancreas to secrete ore insulin. reduces postprandial glucose Side effects: can lead to weight gain. |
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Diabetes. Incretin Mimetic. Leads to higher secretion of insulin, slows gastric emptying. |
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NSAID Selectively COX 2 inhibitor. Less selective than viox- off mkt. |
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More COX 1 than COX 2 inhibition. Only NSAID with no risk of MI. Less effective for pain. |
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Proton pump inhibitor. Take with NSAIDS if Peptic Ulcer Disease. Stops pumping acid into ST. For HT burn, peptic ulcer disease. |
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Not an NSAID. A COX 3 inhibitor. Hepatotoxic. No significant anti inflammatory properties. |
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ANticoagulant. Inhibits clotting. treats atrial fibrillation that leads to stroke. Side effects: Excessive bleeding. Inhibits synthesis of Vitamin K dependent clotting factors. |
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For Osteoporosis A Bisphosphonate. Toxic to osteoclasts- less resoprtion of bone. Side effect: Esophageal irritation, osteonecrosis of jaw. |
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Erythromycin, Clarythromycin, Azithromycin |
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Macrolide Antibiotics Inhibit protein synthesis in microorganisms. Mainly for pneumonia, STDs, sinusitis, etc. Side effects: GI problems, nausea. |
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High Cholesterol. Statin. Improve HDL, lower LDL, stabilize plaque. Inhibit a step in cholesterol synthesis. |
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Antiplatelet drug stronger than aspirin. For if allergic. |
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Leucotriene inhibitor. For asthma. |
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Antibiotic. Inhibits protein synthesis. |
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Most powerful statin on market |
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Asthma. Beta agonist with topical steroid |
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NSAID. Inhibits COX 1 and 2. |
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3 types of drugs that lower bp, decrease progression of diabetic KD disease, slow HT failure and decrease progression of HT failure. |
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ACE inhibitors, beta blockers, ARBs |
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Potential side effects of NSAIDS |
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nephritis, GI toxicity, decreasing uterine motility, HTN |
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If a patient with peptic ulcer disease needs NSAIDs and is not taking a selective COX 2 inhibitor, what should be added to avoid making it worse? |
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Rennin -angiotensin pathway ACE inhibitors, ARBs |
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LV produces angiotensinogen which is activated by rennin into angiotensin 1, which is activated into angiotensin 2 by angiotensin converting enzyme. This then goes to the angiotensin receptors, which |
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