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Pharmacology
Pharmacology
48
Health Care
Graduate
08/09/2010

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Term
Neurontin
Definition
Anticonvulsant for Bipolar disorder, neuropathic pain.
Sodium channel blocker.
Term
Lyrica
Definition
Anticonvulsant for Bipolar disorder. Calcium channel blocker. Used for fibromyalgia.
Term
Depakote
Definition
For Bipolar
Sodium channel blocker, anticonvulsant.
Inhibiting sodium channels doesn't allow sodium ions to promote electrical flow down axon. Inhibits neurons.Inhibits flare of mania.
Side effects: sedative, cognitive effects
Term
Lamictal
Definition
Neuropathic pain, bipolar, anticonvulsant, depressive episodes
Sodium channel blocker
Term
DIlantin
Definition
Sodium channel blocker
Anticonvulsant for seizures, trigeminal neuralgia
Term
Seroquel
Definition
Antipsychotic. tranquilizer. Inhibit dopamine pathways.
SIde Effects: less Parkinson's side effects than Haldol
Term
Haldol
Definition
Old generation antipsychotic
Inhibit dopamine pathways.
Side effects: Parkinson like. Tardive diskinesia- irreversible.
Term
Hydrochlorothiazide
Definition
Thiazide type diuretic
For HTN. Impairs sodium, chloride reabsorption in distal tubule. Low ceiling, long lasting
Side effects: Hypokalemia
Term
Lasix (Furosamide)
Definition
Loop Diuretic. Blocks sodium, chloride channels in Loop of Henle. High ceiling.
For HT failure, edema, less common for HTN
Term
Lisinopril
Definition
ACE inhibitor (Angiotensin Converting Enzyme)Decreases effects of Angiotensin 2 which raises bp.
For HTN
Also prolongs life in HT failure by prevent release of neurotransmitters that are toxic to HT.
Side effect: dry cough
Term
Diovan
Definition
ARB (angiotensin receptor blocker)
Decrease effect of A2 by blocking the receptors.
For HTN. Also improves survival rate with HT failure.
Term
Metoprolol
Definition
Selective Beta blocker.
Block beta 1 adrenergic receptors. Decreases contractility of HT to decrease bp.
Treats HBP
Side effects: erectile dysfunction, bradycardia, fatigue, exercise intolerance
Term
Propanolol
Definition
Beta blocker. Nonselective. Rarely used for HTN. Mostly for migraines, stage fright.
Term
Amlodipine (Norvasc)
Definition
Calcium channel blocker for HTN.
Term
Digoxin
Definition
Cardiac Glycoside.
For HT failure.
Makes HT pump faster, increases contractility of HT, inhibits sodium potassium pump in HT. Many side effects (seeing yellow)
Term
Acarbose/ Precarbose
Definition
For Diabetes.
Alpha glucosidase inhibitors.
Inhibit enzyme that breaks dwon starch into simple sugars.
Side effects: flatulence.
Term
Metformin
Definition
Diabetes.
A Biguinide. Sensitizes LV to insulin. Controls fasting glucose. Leads to weight loss, reduces HT attacks.
Term
Actos
Definition
Diabetes.
A TZD
Sensitizes muscles to insulin. Instructs them to take up glucose more effectively.
Side effects: Fluid Retention, HT failure
Term
Glimepiride
Definition
DIabetes:
Insulin Secretagogue. Tells pancreas to secrete ore insulin. reduces postprandial glucose
Side effects: can lead to weight gain.
Term
Byetta
Definition
Diabetes.
Incretin Mimetic.
Leads to higher secretion of insulin, slows gastric emptying.
Term
Celebrex
Definition
NSAID
Selectively COX 2 inhibitor. Less selective than viox- off mkt.
Term
Alleve/ Naprosyn
Definition
More COX 1 than COX 2 inhibition. Only NSAID with no risk of MI. Less effective for pain.
Term
Prilosec
Definition
Proton pump inhibitor. Take with NSAIDS if Peptic Ulcer Disease.
Stops pumping acid into ST.
For HT burn, peptic ulcer disease.
Term
Acetominophen (tylenol)
Definition
Not an NSAID. A COX 3 inhibitor. Hepatotoxic. No significant anti inflammatory properties.
Term
Warfarin
Definition
ANticoagulant. Inhibits clotting. treats atrial fibrillation that leads to stroke.
Side effects: Excessive bleeding.
Inhibits synthesis of Vitamin K dependent clotting factors.
Term
Fosamax`
Definition
For Osteoporosis
A Bisphosphonate.
Toxic to osteoclasts- less resoprtion of bone.
Side effect: Esophageal irritation, osteonecrosis of jaw.
Term
Erythromycin, Clarythromycin, Azithromycin
Definition
Macrolide Antibiotics
Inhibit protein synthesis in microorganisms. Mainly for pneumonia, STDs, sinusitis, etc.
Side effects: GI problems, nausea.
Term
Hydrocodone
Definition
Opioid.
Term
Lipitor
Definition
High Cholesterol.
Statin.
Improve HDL, lower LDL, stabilize plaque.
Inhibit a step in cholesterol synthesis.
Term
Levothyroxine
Definition
Thyroid hormone
Term
Amoxicillin
Definition
Antibiotic
Term
Nexium
Definition
Proton Pump inhibitor
Term
Plavix
Definition
Antiplatelet drug stronger than aspirin. For if allergic.
Term
Singulair
Definition
Leucotriene inhibitor. For asthma.
Term
Lexapro
Definition
SSRI
Term
Synthroid
Definition
thyroid supplement
Term
Proair
Definition
asthma.
Beta 2 agonist
Term
Simvastatin
Definition
Statin
Term
Azithromycine
Definition
Antibiotic. Inhibits protein synthesis.
Term
Crestor
Definition
Most powerful statin on market
Term
Advair
Definition
Asthma.
Beta agonist with topical steroid
Term
Ibuprofin
Definition
NSAID. Inhibits COX 1 and 2.
Term
Sertraline/ Zoloft
Definition
SSRI
Term
3 types of drugs that lower bp, decrease progression of diabetic KD disease, slow HT failure and decrease progression of HT failure.
Definition
ACE inhibitors, beta blockers, ARBs
Term
2 Antiplatelet drugs
Definition
Aspirin, Plavex
Term
Potential side effects of NSAIDS
Definition
nephritis, GI toxicity, decreasing uterine motility, HTN
Term
If a patient with peptic ulcer disease needs NSAIDs and is not taking a selective COX 2 inhibitor, what should be added to avoid making it worse?
Definition
Proton pump inhibitor
Term
Rennin -angiotensin pathway
ACE inhibitors, ARBs
Definition
LV produces angiotensinogen which is activated by rennin into angiotensin 1, which is activated into angiotensin 2 by angiotensin converting enzyme. This then goes to the angiotensin receptors, which
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