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pharmacology
exam 4
80
Nursing
Professional
04/14/2012

Additional Nursing Flashcards

 


 

Cards

Term
hydrochlorothiazide
Definition
thiazide diuretic
Term

hydrochlorothiazide

 

 

treats?

Definition
ascites, edema, HF, HTN, nephritic syndrome
Term

hydrochlorothiazide

 

therapeutic effects?

Definition
lowered BP
Term

hydrochlorothiazide

 

 

adverse effects?

Definition

hypotension, palpations, dizziness, musculoskeletal weakness or cramping, ototoxicity,

 

hyperglycemia (diabetics)

 

agranulocytosis

Term

hydrochlorothiazide

 

contraindications?

Definition

anuria or prior hypersensitivies

 

pre-eclampsia or other preg induced HTN

Term

hydrochlorothiazide

 

interactions?

Definition

reduce effects of anticoagulants, sulfonyluureas, antidiabetic drugs (insulin)

 

risk of renal toxicity from NSAIDs

 

decreased lithium toxicity

Term

hydrochlorothiazide

 

overdose?

Definition
treated with infusion of electrolytes--prevents dehydration and hypotension
Term

furpsemide

 

pharm class?

Definition
loop diuretic
Term

furpsemide

 

 

treats?

Definition
actue HF--removes large amounts of fluids quickly
Term

furpsemide

 

adverse effects?

Definition

hypokalemia

 

dehydration and hypotension

 

hypovalemia may cause orthostatic hypotension and syncope

Term

furpsemide

 

 

contraindications?

Definition
anuria, hepatic coma, severe fluid or electrolyte depletion
Term

furpsemide

 

 

interactions?

Definition
use with corticosteroids, amphotericin B, or K+ depleting drugs can = hypokalemia
Term

furpsemide

 

overdose?

Definition
hypotension and severe fluid/electrolyte loss--treated with fluids and admin of vasopressors
Term

chlorothiazide

 

 

pharm class?

Definition
thiazide diuretic
Term

 

chlorothiazide

 

treats?

Definition
fluid retention due to HF, liver disease, and corticosteroid/estrogen therapy
Term

chlorothiazide

 

adverse effects?

Definition
thirst, weakness, lethargy, muscle cramping, hypotension, and tachycardia--due to excess water loss
Term

chlorothiazide

 

contraindications?

Definition
anuria, hypokalemia, severe hepatic/renal impairment, hypersensitivity to sulfonamides
Term

chlorothiazide

 

interactions?

Definition
concurrent use with digoxin may cause toxicity due to increased K and mag
Term

chlorothiazide

 

 

overdose?

Definition
fluids/electrolytes
Term

spironolactone

 

 

pharm class?

Definition
K sparing diuretic, aldosterone antagonist
Term

spironolactone

 

 

treats?

Definition
mild HTN--reduce edema associated with kidney/liver disease and effective in slowing the progression of HF
Term

spironolactone

 

 

admin?

Definition
give with food to increase absorption
Term

spironolactone

 

 

adverse effects?

Definition
hyperkalemia--fatigue, muscle weakness, bradycardia
Term

spironolactone

 

 

adverse effects (men)

Definition
gynecomastia, impotennce, diminished libido
Term

spironolactone

 

 

adverse effect (women)

Definition
menstrual irregularities, hirsutism, and breast tenderness
Term

spironolactone

 

 

contraindicatios?

Definition

pregnancy and lactation

 

anuria, significant impairment of renal function, or hyperkalemia

Term

spironolactone

 

 

interactions?

Definition

ammonium chlorid= acidosis

 

aspirin/salicylates= decrease diuretic effect

 

may decrease effects of digoxin

Term

patients taking K wasting

(thiazides, thiazide-like, loop diuretics)

 

 

 

good foods?

Definition

strawberry, bananas, dried apricots/prunes, tomatoes, beets, dried beans, OJ, grapefruit/prune juice and fresh meat

 

GOOD SOURCES OF K

Term

K sparing diuretics

 

 

 

avoid foods?

Definition
anything high in K--gatorage/powerade
Term

gout prone patients

 

 

avoid foods?

Definition
shell fish, organ meats(liver/kidneys), alcohol, and high fructose beverages
Term
patient taking diuretics should report immediaatley?
Definition

signs of diabetes(polydipsia, polyphagia) elevated blood sugar

 

flu-like symptoms, persistent tinnitus, balance/coord problems

 

weight gain more than 2lbs in 24 hrs

Term

digoxin

 

Therapeutic: drug for HF

 

 

pharm class?

Definition
cardiac glycoside
Term

digoxin

 

Therapeutic: drug for HF

 

 

treats?

Definition
dysrythmias, alleviates symptoms of HF, pulmonary congestion, and peripheral edema
Term

digoxin

 

Therapeutic: drug for HF

 

 

actions/uses?

Definition

increase contractility or strength of myocardial contraction

(positive inotropic action)

 

inhibits Na/K ATPase

Term

digoxin

 

Therapeutic: drug for HF

 

 

admin alerts?

Definition

use caution with geriatric/pediatric patient

(inadequate renal/hepatic metabolic enzymes)

 

positive inotrope and slows heart rate at it strengthens contactility

Term

digoxin

 

Therapeutic: drug for HF

 

 

adverse effects?

Definition

Most Dang: ability to creat dysrythmias--especially in patients with hypokalemia or impaired renal funct

 

nausea, vomiting, fatigue, anorexia and visual disturb

(report immediately)

Term

digoxin

 

Therapeutic: drug for HF

 

 

contraindicatiosn?

Definition

patients with AV block or ventricular dysrythmias

 

older adults, patients with impaired renal function, MI, cor pulmonale, or hypothyrodism

Term

digoxin

 

Therapeutic: drug for HF

 

 

interactions?

Definition

decrease effects: ACE inhibitor, spironolactone, K supp can lead to hyperkalemia

 

quinidine, verapamil, amiodarone, and alprazolam will decrease the distribution and excretion increasing risk of toxicity

Term

digoxin

 

Therapeutic: drug for HF

 

herbal/foods?

Definition

ginseng may increase risk of toxicity

 

Ma huang and ephedra may incuce dysrhythmias

Term

digoxin

 

Therapeutic: drug for HF

 

 

overdose?

Definition

can be fatal

 

(digibind)- IV fusion

Term

digoxin

 

Therapeutic: drug for HF

 

 

patient knowledge?

Definition

increase K rish foods: bananas, apricots, kidney beans, sweet potatoes, and peanut butter

 

 

Immediately report: severe SOB, frothy sputum, profound fatigue, swellling extremities [ heart failure]

 

sign of HF: increasing dypsnea/postrual nocturnal dyspnea, rales or "crackles" in lungs, frothy pink-tinged sputm

Term

digoxin

 

Therapeutic: drug for HF

 

 

patient and meds?

Definition

take only exact dose--do NOT double up if missed dose

(small amounts results in toxicity)

Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

pharm class?

Definition
organic nitrate
Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

therapeutic effects?

Definition

chest pain subsides/lessens, heart rate/BP remain WNL, and ECG remains WNL w/o signs of ischemia/infarct

 

 

* preload/afterload diminish, decreasing the workload of the heart and decreasing myocardial O2 need, chest pain diminishes

Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

admin alerts?

Definition

use glass bottle and special tubing

 

avoid exposure to light

Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

interactions?

Definition
concurrent use with viagra/levitra may cause life threatening hypotension and cardiovascular collapse
Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

overdose?

Definition
reversed with admin of IV normal saline
Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

 

patient knowledge

Definition

use pain rating scale b4/after to asses for relief

 

report changes in: character, severity, or frequency of angina episode

 

Report: dizziness, faintness, palpations, or headaches

Term

Nitroglycerin

 

Therapeutic: Anti-anginal drug

 

patient knowledge (2)

Definition

always remove old patch, clean skin and rotate sites

 

IMMED Report: changes in mental status, LOC, dizziness, dyspnea, increasing productive cough (frothy sputum)

 

lung congestion may signal impending HF

Term

procainamide

 

therapeutic: anti-dysrythmic

 

 

pharm class?

Definition
Na channel blocker/ Class 1
Term

procainamide

 

therapeutic: anti-dysrythmic

 

action/uses?

Definition

broad-spectrum dru-corrects many types of atrial/ventricular dysrythmias

 

reduce automaticity and slowing conduction of the action potential across the myocardium

Term

procainamide

 

therapeutic: anti-dysrythmic

 

admin alerts?

Definition
use supine postion during IV admin b/c severe hypotension may occur
Term

procainamide

 

therapeutic: anti-dysrythmic

 

 

adverse effects?

Definition

nausea, vomiting, abdominal pain, hypotension, and headaches

 

high dose may produce CNS effects (confusion/psychosis)

Term

procainamide

 

therapeutic: anti-dysrythmic

 

contraindications?

Definition
patients with complete AV block, severe CHF, blood dyscrasis, and myasthenia gravis
Term

procainamide

 

therapeutic: anti-dysrythmic

 

 

interactions?

Definition
anticholinergic/anti-dysrythmics if use concurrently will increase effects
Term

procainamide

 

therapeutic: anti-dysrythmic

 

overdose?

Definition
targeted at reversing hypotension with vasopressors and treat/prevent dysrythmias
Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

pharm?

Definition
beta-andrenergic antagonist
Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

 

treats?

Definition
hypertension, angina, migraine headaches and prevention of MI
Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

admin alerts?

Definition

abrupt DC may cause MI, severe hypertension, and ventricular dysrythmias

 

if pulse is below 60/min (notify provider)

Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

adverse effects?

Definition

fatigue, hypotension, bradycardia

 

males: diminished libido/imptence (nonadherence)

 

diabetics: mask hypoglycemia

 

renal impairment=toxicity

Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

 

contraindications?

Definition

cardiogenic shock, sinus bradycardia

(depressive effect on heart)

 

COPD/asthma=constricts smooth muscles of airway

Term

propanolol

 

therapeutic: class 2 anti-dysrythmic

 

 

interactions?

Definition

not given within 2 weeks of MAOI

(severe bradycardia/hypotension)

 

ethanol/antacids containing aluminum hydroxide gel

(slow absorption)

Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

pharm class?

Definition
K channel blocker
Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

treat?

Definition

resistant ventricular tachycardia that may prove life-threatening

 

drug of choice for atrial dysrythmias in pts with HF

Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

admin alerts?

Definition
hypokalemia/hypomagnesium should be correct prior to therapy
Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

adverse effects?

Definition

most serious: pneumonia-like syndrome

 

blurred vision, rashes, photsensitivity, nausea, vomiting, anorexia, fatigue, dizziness, hypotension

Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

interactions?

Definition

enhances effect of anticoagulants

 

increase serum digoxin 70%

Term

amiodarone

 

therapeutic class: class 3- antidysrythmic

 

 

overdose?

Definition

atropine or isoproterenol= reverse bradycardia

 

vasopressors= reverse hypotension

Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

pharm class?

Definition
CCB
Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

action/uses?

Definition

vessels: CCBs lower BP, reducing cardiac workload

 

heart: slows conduction velocity, stabilizes dysrythmias

 

dilates coronary arteries: important with angina

Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

admin?

Definition
ensure solution is clear and colorless
Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

 

contraindications?

Definition

AV heart block, sick sinus bradycardia, severe hypotension, bleeding aneurysm, intracranial surgery

 

renal/hepatic impairment

Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

adverse effects?

Definition
headaches, constipation, hypotension
Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

interactions?

Definition

elevate blood levels of digoxin

 

beta blockers/antiHTN= hypoTN effect

Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

food?

Definition

grapefruit juic increases levels

 

hawthorn may add to hypoTN effects

Term

verapamil

 

therapeutic: class 4, anti-dysrythmic

 

 

overdose?

Definition
calcium salts
Term

Antidysrythmic meds

 

 

patient knowledge

Definition

brady/tachycardia-new/different dysrythmias

(report IMMEDIATELY)

 

first dose effect= orthostatic hypoTN

 

weight gain/edem=cardiovascular disease

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