Term
What is the term for unpredictable and unexplained drug reactions?
a. adverse reactions
b. idiosyncratic reactions
c. enzyme-specific reactions
d. unaltered reactions |
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Definition
| Idiosyncratic reaction - b |
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Term
A drug that occupies a receptor site and prevents endogenous chemicals from acting is called a/an:
a. antagonist
b. partial agonist
c. agonist
d. protagonist |
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Definition
| antagonist - a; an antagonist occupies a receptor site and prevents endogenous chemicals from acting. An agonist produces the same type of response as the endogenous substance. A partial agonist is a medication that produces a weaker response than an agonist. |
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Term
In considering the pharmacotherapeutic perspective, which property is considered to be of most importance?
a. potency
b. efficacy
c. toxicity
d. interaction with other drugs |
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Definition
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Term
The term used to describe the magnitude of maximal response that can be produced from a particular drug is:
a. efficacious
b. toxic
c. potent
d. comparable |
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Definition
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Term
Morphine has a greater efficacy than either of the OTC drugs, aspirin or acetaminophen. Base on what the nurse knows about efficacy, what patient condition might require a dose of morphine rather than aspirin or acetaminophen?
a. a patient who is in mild pain but does not like to take aspirin or acetaminophin
b. a patient who routinely uses acetaminophen at home for pain relief
c. a patient who quickly develops allergies to multiple medications
d. a patient in moderate to severe pain after the other drugs have been ineffective for pain relief |
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Definition
| d. a patient in moderate to severe pain after the other drugs have been ineffective for pain relief |
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Term
| if the ED50 is the dose required to produce an effective response in 50% of a group of patients, what happens in the other 50% of the patients after a dose has been administered? |
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Definition
| the other 50% of the population did not experience the desired effect from the dose |
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Term
| Two drugs competing for a receptor on a mast cell that will cause the release of an agonist versus an antagoniston this receptor. Which would likely be called an antihistamine, the agonist or the antagonist? |
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Definition
| An agonist binds to the receptor site and produces the same or a greater response than the engogenous chemical. An antagonist occupies a receptor site and prevents the endogenous substance from acting. Antagonists compete with agonists for binding sites. An antihistamine would most likely be an antagonist |
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Term
A nurse reads that the drug to be given has a "narrow therapeutic index." This means that the drug:
a. has a narrow range of effectiveness and may not give this patient the desired therapeutic results
b. has a narrow safety margin and even a small increase in dose may produce adverse or toxic effects
c. has a narrow range of conditions or diseases that the drug will be expected to treat successfully.
d. has a narrow segment of the population for whom the drug will work as desired. |
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Definition
| has a narrow safety margin and even a small increase in dose may produce adverse or toxic effects - b |
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