Opioids: (MU/KAPPA receptor)

Moderate-sever pain (analgesia)

CNS effects:S&S: Stupor-like sedating effects, Decreased GI Motility, Miosis (constricting pupils), Dependency, Respiratory depression

MU receptors    

Morphine

Meperidine (Demerol)

Hydromorphone (Dilaudid)

Oxycodone

Hydrocodone (Tramdol, Ultram)

Codeine

Mixed (MU or KAPPA)   

- Buprenorphine (suboxone)

- Nubain

Combination Analgesic (Opioid + acetaminophen or ASA)

-Vicodin

-Percocet/Percodan

-Darvocet

-Tylenol #3

Toxic effects occur when mixing OTC medications with combination drugs (acetaminophen)

Opioid Antagonist    

Narcan (Reverses MU/KAPPA receptor drugs)

NSAIDs:  Non-Opioid (used for: analgesia, anti-inflammatory, antipyretic)

Cox-1:

- Aspirin

- Ibuprofen (advil, motrin)

- Naproxen (Aleve, Anaprox)

- Neloxican (Mobic)

Cox-2: (more specific/selective/pain, inflammation

-Celecoxib (Celebrex)

Adverse Reaction Cox1/Cox2:  GI bleeding, Ulcers, kidney damage (Nephrotoxic) (Cox1>Cox2)

Non-opioid analgesic:

- Acetaminophen (Tylenol)

Migraine:

- Triptans (constrict blood vessels/brain), Ergot Alkaloids, Beta-adrenergic blockers, calcium channel blockers, antidepressants (TCAs), anti-seizure drugs

- Imitrex: (Triptan) to terminate migraine

Attention Deficit Hyperactivity Disorder (ADHD)

CNS Stimulant: Schedule Drug                      

- Amphetamine (Adderall)

                 - Methylphenidate (Concerta)

Side Effect: Loss of Appetite