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Pharmacology
Autonomic drugs
78
Pharmacology
Graduate
01/17/2014

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Cards

Term
nicotinic receptors
Definition
Na/K channels
Term
muscarinic receptors
Definition
GPCR
Term
Gq
Definition
H1, a1, V1, M1, and M3
Term
Gs
Definition
B1, B2, D1, H2, V2
Term
Gi
Definition
M2, a2, D2
Term
increases vascular smooth muscle contraction
Definition
a1 and V1
Term
decrease sympathetic outflow
Definition
a2
Term
increase HR
Definition
B1
Term
vasodilation, bronchodilation and decrease uterine tone
Definition
B2
Term
entereic nervous system
Definition
M1
Term
decrease HR
Definition
M2
Term
increase bladder contraction, bronchoconstriction
Definition
M3
Term
relaxes vascular smooth mm
Definition
D1
Term
increase nasal and bronchial mucus production
Definition
H1
Term
increase gastric acid
Definition
H2
Term
increase H2O permeability and reabsorption
Definition
V2
Term
inhibits choline transfer into neuron
Definition
hemicholinium
Term
inhibits ash into vesicle
Definition
vesimacol
Term
inhibit Ach release
Definition
botulinum
Term
stimulate Ach release
Definition
black widow spider toxin
Term
inhibit tyrosine hydroxylase
Definition
metyrosine
Term
inhibit dopamine into vesicle
Definition
reserpine
Term
inhibits NE release
Definition
quanethidine
Term
activates NE release
Definition
amphetamines, ephedrine, tyramine
Term
inhibits NE reuptake
Definition
cocaine, TCAs
Term
autorecpetors for adrenergic
Definition
a2, M2 an ATII
Term
post operative, neurogenic ileus
Definition
bethanechol, neostigmine
Term
urinary retention
Definition
bethanecol, neostigmine
Term
glaucoma
Definition
carbechol, physostigmine, echothiphate
Term
glaucoma emergency
Definition
pilocarpine
Term
asthma diagnosis
Definition
methacholine
Term
myasthenia gravis
Definition
neostigmine, pyridostigmine
Term
diagnosis of myasthenia gravis
Definition
edrophonium
Term
glaucoma
Definition
Term
alzheimers
Definition
donepezil, rivastigmine, galantamine
Term
cholinesterase inhibitor poisoning antidote
Definition
atropine and pralidoxime
Term
symptoms of increased Ach
Definition
diarrhea, urination, miosis, bronchospasm, bradycardia, excitation of skeletal mm, lacrimation, sweating, and salivation
Term
mydriasis and cycloplegia at eye doctor
Definition
atropine, homatropine tropicamide
Term
parkinsons
Definition
benztropine
Term
motion sickness
Definition
scopolamine
Term
asthma, COPD
Definition
ipratropium
Term
reduce urge incontinence
Definition
oxybutinin, tolteridine, solifenesin, darifenesin, trospium
Term
antimuscarinic side effects
Definition
hot as a hare, dry as a bone, red as a beet, blind as a bat, mad as a hatter
Term
thymus pathology with myasthenia gravis
Definition
hyperplasia, atrohy and thymoma
Term
epinephrine receptors
Definition
alpha-1, alpha 2 beta1 and beta2
Term
norepinephrine receptors
Definition
alpha1 alpha 2 and beta1
Term
isoproterenol receptors
Definition
beta1 and beta2
Term
dopamine receptors
Definition
alpha1 and 2 (high), beta 1 and 2 (med), D1 (low)
Term
dobutamine receptors
Definition
beta2 > beta 1
Term
septic shock
Definition
NE
Term
cardiogenic shock
Definition
dobutamine
Term
anaphylactic shock
Definition
epinephrine
Term
reduce premature uterine contractions
Definition
terbutaline
Term
beta2 agonists
Definition
albuterol, metaproterenol, salmeterol, terbutaline
Term
amphetamine
Definition
indirect, release store catecholamines; narcolepsy, ADHD, obesity, MDD
Term
ephedrine
Definition
releases stored catecholamiens, nasal decongestion, urinary incontinence, hypotension
Term
cocain
Definition
inhibits uptake, vasoconstriction and local anesthesia
Term
NE effects on HR and BP
Definition
inreases BP and decreases HR (Reflex)
Term
epi effects on HR and BP
Definition
increases BP and HR
Term
isoproterenol effects on BP and HR
Definition
decreases BP and increases HR
Term
clonidine and methyldopa MOA
Definition
alpha-2 agonists, decrease adrenergic outflow
Term
HTN in renal disease
Definition
alpha2 agonists
Term
phenoxybenzamine
Definition
pheochromocytoma, irreversible
Term
phentolamine
Definition
to pts on MAO inhibitors who eat tyramine-containing food
Term
orthostatic hypotension, reflex tachy
Definition
alpha blockers
Term
prazosin, terazosin, doxazosin
Definition
alpha1; HTN, BPH
Term
1st dose orthostatic hypotension
Definition
alpha1 inhibitors
Term
mirtazapine
Definition
alpha2; depression
Term
uses of beta blockers
Definition
HTN, angina, MI, SVT, CHF, glaucoma
Term
beta blocker toxicity
Definition
impotence, asthma, bradycardia, AV block, CHF, sedation, caution in DM
Term
B1 antagonists
Definition
acebutolol, betaxolol, esmolol, atenolol, metoprolol
Term
nonselective beta blockers
Definition
propranolol, timolol, nadolol, and pindolol
Term
nonselective alpha and beta antagonists
Definition
carvedilol and labetalol
Term
partial beta agonists
Definition
pindolol and acebutolol
Term
post MI beta blockers
Definition
metoprolol and carvedilol
Term
anti-HTN DOC with aortic dissection
Definition
beta blocker
Term
CHF beta blocker
Definition
esmolol
Term
alpha-1ad antagonist
Definition
tamsulosin, BPH
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