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Pharmacology
Exam #3
188
Veterinary Medicine
Undergraduate 3
03/03/2013

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Cards

Term
What is a loop diuretic?
Definition
Furosemide
Term
What's a potassium sparing diuretic?
Definition
Spironolactone
Term
What's an osmotic diuretic?
Definition
Mannitol
Term
What're 2 agents for urinary incontinence/retention?
Definition
Imipramine and phenlypropanolamine
Term
What is a urinary alkalizer?
Definition
Sodium bicarbonate
Term
What are 2 urinary acidifiers?
Definition
Methionine and ammonium chloride
Term
What is a cholinergic stimulant diuretic?
Definition
Bethanechol
Term
What are 2 agents for urolithiasis?
Definition
Allopurinol and methionine
Term
What 2 thiazide drugs are used as diuretics and to help congestive heart failure edema?
Definition
Chlorothiazide and hydrochlorothiazide
Term
What's the generic for chlorothiazide?
Definition
Diuril
Term
What's the generic of Hydrochlorothiazide?
Definition
HydroDIURIL
Term
What thiazide diuretics work by blocking sodium reabsorption and promoting chloride excretion in the distal convoluted tubules?
Definition
Chlorothiazide and hydrochlorothiazide
Term
What thiazide diuretics can cause hypokalemia (K deficiency) and cardiac dysfunction in prolonged use?
Definition
Chlorothiazide and hydrochlorothiazide
Term
What're the 3 generics for furosemide?
Definition
Lasix, Disal, and Diuride
Term
What diuretic works by blocking reabsorbtion of electrolytes in the loop of Henle?
Definition
Furosemide
Term
What loop diuretic is used as a diuretic, congestive heart failure, pulmonary edema, and hypertension?
Definition
Furosemide
Term
What loop diuretic can have side effects of electrolyte imbalances and hypokalemia that can lead to arrhythmias?
Definition
Furosemide
Term
What drug is used as a mild diuretic or in combination with other drugs?
Definition
Spironolactone
Term
What potassium-sparing diuretic works by acting on the distal convoluted tubules to promote sodium and water excretion and potassium retention?
Definition
Spironolactone
Term
What's the main side effect of potassium-sparing Spironolactone?
Definition
Hypokalemia
Term
What's the generic of spironolactone?
Definition
Aldactone
Term
What are 2 generics of mannitol?
Definition
Osmitrol and Mannitol
Term
What diuretic works by increasing the osmolality of the filtrate in the renal tubules?
Definition
Mannitol
Term
What osmotic diuretic is used to prevent kidney failure, decrease intercranial pressure, and to decrease interocular pressure?
Definition
Mannitol
Term
Though uncommon, what osmotic diuretic can cause fluid/electrolyte imbalance and vomiting?
Definition
Mannitol
Term
What are the 2 generics of methionine?
Definition
Methio-tabs and Methigel
Term
What's the generic of ammonium chloride?
Definition
Uroeze
Term
What 2 drugs are used to dissolve and help prevent formation of struvite crystals and treat urolithiasis?
Definition
Methionine and Ammonium chloride
Term
What 2 diuretics work by acidifying urine to dissolve uroliths?
Definition
Methionine and Ammonium Chloride
Term
What urine acidifiers can cause loss of appetite, nausea, vomiting, and diarrhea?
Definition
Methionine and ammonium chloride
Term
What's the generic for imipramine?
Definition
Tofranil
Term
What urinary incontinence agent can cause sedation, tachycardia, and tremors?
Definition
Imipramine
Term
What renal drug is mainly used for urinary incontinence, cataplexy, narcolepsy, and ejaculatory dysfunction in horses?
Definition
Imipramine
Term
What urinary incontinence agent works by blocking the amine pump, increasing neurotransmitter levels, and some anticholinergic activity?
Definition
Imipramine
Term
What're the 2 generics for phenylpropanolamine?
Definition
Proin and Propagest
Term
What incontinence drug works by being an aplha- and beta-adrenergic What incontinence drug is used for stress incontinence, and is sometimes used before resorting to hormonal agonist that increases urethral tone?
Definition
Phenylpropanolamine
Term
What are the 3 main side effects of the incontinence drug, phenylpropanolamine?
Definition
Anorexia, restlessness, and hypertension
Term
What's the generic of sodium bicarbonate?
Definition
Sodium bicarbonate
Term
What urinary alkalinizer is used to treat calcium oxylate, cystine, and ammonium urate uroliths?
Definition
Sodium bicarbonate
Term
Although rare, what are 2 side effects of sodium bicarbonate?
Definition
Metabolic alkalosis and hypokalemia
Term
Urecholine, Duvoid, and Urabeth are generics for what cholinergic stimulant?
Definition
Bethanechol
Term
What are 2 main side effects of Bethanechol?
Definition
Vomiting and diarrhea
Term
What drug works by the cholinergic agonists binds to the receptors on smooth muscles, allowing sodium and calcium to enter the cells to allow increased muscle control?
Definition
Bethanechol
Term
What cholinergic stimulant is used for neurologically-caused incontinence?
Definition
Bethanechol
Term
What are 2 generics of Allopurinol?
Definition
Zyloprim and Lopurin
Term
What urinary drugs works by decreasing uric acid production?
Definition
Allopurinol
Term
What uric acid decreasing drug is used to help prevent the formation of ammonium urate uroliths?
Definition
Allopurinol
Term
What are 2 side effects of Allopurinol?
Definition
GI effects and hypersensitivity
Term
What are 2 penicillin cell wall agents?
Definition
Amoxicillin and ampicillin
Term
What are 2 cephalosporin cell wall agents?
Definition
Cefazolin and Cephalexin
Term
What type of antibiotics are cell membrane agents?
Definition
Polymixins
Term
What is a cell protein blocking aminoglycoside?
Definition
Amikacin
Term
What is a cell protein blocking tetracycline?
Definition
Doxycycline
Term
What’s a cell nucleic acid blocking quinolone?
Definition
Flumequine
Term
What’s a cell nucleic acid blocking fluoroquinolone?
Definition
Enrofloxacin
Term
What are 2 antimetabolite sulfonamides?
Definition
Sulfamethoxazole
Term
What are the 2 generics of amoxicillin?
Definition
Amoxil and Amoxi-Tabs
Term
What 2 penicillins work by inhibiting cell wall synthesis?
Definition
Amoxicillin and ampicillin
Term
What antibiotic is used to treat a variety of infections, but is ineffective against bacteria that produce beta-lactamase?
Definition
Amoxicillin
Term
What 2 cell wall inhibiting penicillin has side effects of hypersensitivity and GI effects?
Definition
Amoxicillin and ampicillin
Term
What’s the generic of ampicillin?
Definition
Polyflex
Term
What cell wall inhibiting penicillin is used to treat enterococci, particulary E. faecium?
Definition
Ampicillin
Term
What cephalosporin antibiotics are used to treat respiratory, skeletal, genitourinary, skin, and soft tissue infections caused by susceptible bacteria?
Definition
Cefazolin and cephalexin
Term
What cephalosporin antibiotics have side effects of diarrheam vomiting, phlebitis, and myositis?
Definition
Cefazolin and cephalexin
Term
What are 3 generics of Cefazolin?
Definition
Ancef, Kefzol, and Zolicef
Term
What cephalosporins work on gram positive bacteria by inhibiting mucopeptide synthesis in cell wall synthesis?
Definition
Cefazolin and cephalexin
Term
What’s the generic for cephalexin?
Definition
Keflex
Term
What are the 2 generics of amikacin?
Definition
Amikin and Amiglyde-V
Term
What aminoglycoside antibiotic is used for a wide variety of bacteria predominantly gram negative aerobic bacilli?
Definition
Amikacin
Term
What aminoglycoside antibiotic works by inhibiting protein synthesis?
Definition
Amikacin
Term
What are 2 side effects of Amikacin?
Definition
Nephrotoxicity and renal tubular necrosis
Term
What’s the generic of Doxycycline?
Definition
Vibramycin
Term
What tetracycline protein synthesis blocking antibiotic is used to treat azotemic patients and a variety of microorganisms?
Definition
Doxycycline
Term
What tetracycline works by blocking cell protein synthesis?
Definition
Doxycycline
Term
What are 2 side effects of doxycycline?
Definition
Vomiting and diarrhea
Term
What quinolone antibiotic works by inhibiting DNA function in the bacteria?
Definition
Flumequine
Term
What quinolone is effective against gram positive and negative bacteria, intestinal infections in livestock, and intracellular pathogens?
Definition
Flumequine
Term
What’s the generic of enrofloxacin?
Definition
Baytril
Term
What fluoroquinolone works by inhibiting DNA function in bacteria?
Definition
Enrofloxacin
Term
What fluoroquinolone is used against gram positive and gram negative bacteria and is reserved until other antibiotics have been tried to maintain its effectiveness against superinfections?
Definition
Enrofloxacin
Term
What fluoroquinolone has side effects of cartilage lesions in growing dogs and GI effects?
Definition
Enrofloxacin
Term
What are the generics of sulfamethoxazole/trimethoprim?
Definition
Co-trimoxazole, Tribrissen, Bactrim, and Septra
Term
What antibiotic is mainly used for prostatic infections and methicillin-resistant staphylococci?
Definition
Sulfamethoxazole/Trimethoprim
Term
What antibiotic works by inhibiting folic acid synthesis and mainly works on gram positive bacteria?
Definition
Sulfamethoxazole/Trimethoprim
Term
What antibiotic can cause side effects of excessive salivation in cats and keratoconjunctivitis sicca in dogs?
Definition
Sulfamethoxazole/Trimethoprim
Term
What 5 antiparasites are used to commonly kill nematodes?
Definition
Dichlorvos, Ivermectin, Moxidectin, Febendazole, and Pyrantel
Term
What antiparasite is used to kill heartworms?
Definition
Milbemycin oxime
Term
What antiparasite is used to kill Cestodes and maybe Trematodes?
Definition
Praziquantel
Term
What are 3 ectoparasite antiparasites?
Definition
Amitraz , Selamectin, and Fipronil
Term
What are 2 anticoccidial antiparasites?
Definition
Amprolium and Sulfadimethoxine
Term
What dewormer has the generics of Task, Wormer, and Atgard?
Definition
Dichlorvos
Term
What dewormer has the generic of Noromectin, Ivomec, Heartgard, and Iverhart?
Definition
Ivermectin
Term
What dewormer has the generics of Interceptor, Safeheart, and Sentinel?
Definition
Milbemycin oxime
Term
What dewormer has the generics of Cydectin, Proheart, and Quest?
Definition
Moxidectin
Term
What dewormer has the generic of Panacur?
Definition
Fenbendazole
Term
What dewormer has the generics of Drontal, Droncit, Praziject, and Cestajet?
Definition
Praziquantel
Term
What dewormer has the generics of Nemex and Strongid?
Definition
Pyrantel
Term
What ectoparasite drug has the generic of Mitaban?
Definition
Amitraz
Term
What ectoparasite drug has the generic of Revolution?
Definition
Selamectin
Term
What ectoparasite drug has the generic of Frontline?
Definition
Fipronil
Term
What anticoccidial drug has the generic of Corid?
Definition
Amprolium
Term
What anticoccidial drug has the generic of Albon?
Definition
Sulfadimethoxine
Term
What are the 2 main side effects of Dichlorvos?
Definition
Vomiting and tremors
Term
What dewormer works by inhibiting acetylcholinesterase?
Definition
Dichlorvos
Term
What dewormer can cause hypersensitivity and shock-like symptoms?
Definition
Ivermectin
Term
What dewormer works by enhancing the release of gamma amino butyric acid?
Definition
Ivermectin
Term
What dewormer can cause shock-like symptoms in animals with circulating microfilaria?
Definition
Milbemycin oxime
Term
What dewormer works by disrupting the neurotransmitter (GABA)?
Definition
Milbemycin oxime
Term
What dewormer can cause a stupor and convulsions?
Definition
Moxidectin
Term
What dewormer works by binding to certain chloride channels to block nerve and muscle action to the parasite?
Definition
Moxidectin
Term
What dewormer has vomiting and diarrhea as the main side effects?
Definition
Fenbendazole
Term
What dewormer works by interfering with the metabolism of the worm?
Definition
Fenbendazole
Term
What anticestodal drug can cause pain at the injection site and anorexia?
Definition
Praziquantel
Term
What anticestodal drug works by interacting with phospholipids in the integument of the tapeworm?
Definition
Praziquantel
Term
What dewormer works by mimicking the action of acetylcholine on the nematode?
Definition
Pyrantel
Term
What’s the main side effect of Pyrantel?
Definition
Vomiting
Term
What ectoparasite drug is primarily used to treat generalized demodicosis?
Definition
Amitraz
Term
What ectoparasite drug has the main side effect of transient sedation?
Definition
Amitraz
Term
What ectoparasite drug works by being an MAO inhibitor and has CNS effects on mites?
Definition
Amitraz
Term
What ectoparasite drug is used to prevent heartworm disease, and control fleas, feline hookworms, ear mites, and sarcoptic mange in dogs?
Definition
Selamectin
Term
What are the 2 main side effects of Selamectin?
Definition
Alopecia at application site and vomiting
Term
What ectoparasite drug works by enhancing chloride permeability and acts on inhibitory neurotransmitters?
Definition
Selamectin
Term
What ectoparasite drug works by blocking the chloride ions through the GABA receptor?
Definition
Fipronil
Term
What are the 2 main side effects of Fipronil?
Definition
Hypersalivation and skin irritation
Term
What ectoparasite drug is best for killing adult fleas?
Definition
Frontline (Fipronil)
Term
What ectoparasite drug works by affecting the coccidia’s metabolism?
Definition
Amprolium
Term
What 2 drugs are used to treat coccidians?
Definition
Amprolium and sulfadimethoxine
Term
What anticoccidian drug works by reducing the amount of oocysts shed?
Definition
Sulfadimethoxine
Term
What are the 2 main side effects of Amprolium?
Definition
Neurologic disturbances and depression
Term
What are the 2 main side effects of Sulfadimethoxine?
Definition
KCS and hypersensitivity
Term
What are glycoaminoglycans also known as?
Definition
Proteoglycans
Term
What type of drugs contain many kinds of polysaccharides and work by cushioning joints or promote the production of joint fluid?
Definition
Glycoaminoglycans
Term
What type of drugs are nutraceutical anti-inflammatory agents?
Definition
Glycoaminoglycans (GAGs)
Term
What type of drug are polysulfated GAGs?
Definition
Glycoaminoglycan
Term
What type of drug is hyaluronic acid?
Definition
Glycoaminoglycan
Term
What type of drug is glucosamine?
Definition
Glycoaminoglycan
Term
What type of drug is chondroitin sulfate?
Definition
Glycoaminoglycan
Term
What nutraceuticals are used to reduce inflammation, promote joint fluid, and maintain cartilage structure in joints?
Definition
Glycoaminoglycans
Term
What type of drugs has the main side effect of localized inflammation?
Definition
Glycoaminoglycans
Term
What's the generic of acetylsalicylic acid?
Definition
Aspirin
Term
What drugs works by inhibiting prostaglandin synthesis?
Definition
Aspirin and Phenylbutazole
Term
What is a salicylate non-steroidal anti-inflammatory drug?
Definition
Aspirin
Term
What NSAID is used to reduce pain, inflammation, and to reduce platelet aggregation?
Definition
Aspirin
Term
What drug has the main side effects of GI effects and anorexia?
Definition
Aspirin
Term
What drug is known as BUTE?
Definition
Phenylbutazole
Term
What drug is a pyrazole NSAID?
Definition
Phenylbutazole
Term
What pyrazolone derivative is used to treat musculoskeletal pain in horses?
Definition
Phenylbutazole
Term
What anti-inflammatory drug has the main side effects of oral and GI erosions and ulcers, diarrhea, and renal necrosis?
Definition
Phenylbutazole
Term
What's are 2 generics of Ibuprofen?
Definition
Motrin and Advil
Term
What's the generic of carprofen?
Definition
Rimadyl
Term
What 2 drugs are propionic acid NSAIDS?
Definition
Ibuprofen and Carprofen
Term
What propionic acid drugs works by blocking cyclooxygenase?
Definition
Ibuprofen and Carprofen
Term
What is the main side effect of ibuprofen and carprofen?
Definition
Mild GI effects
Term
What are ibuprofen and carprofen mainly used for?
Definition
Reducing pain by reducing inflammation
Term
What type of drug is flunixin meglumine?
Definition
NSAID
Term
What type of drug is dimethyl sulfoxide?
Definition
NSAID
Term
What type of drug is deracoxib?
Definition
NSAID
Term
What type of drug is meloxcicam?
Definition
NSAID
Term
What type of drug is firocoxib?
Definition
NSAID
Term
What's the generic of flunixin meglumine?
Definition
Banamine
Term
What's the generic of dimethyl sulfoxide?
Definition
DMSO
Term
What's the generic of deracoxib?
Definition
Deramaxx
Term
What's the generic of meloxcicam?
Definition
Metacam
Term
What's the generic of firocoxib?
Definition
Previcox
Term
What selective COX-2 inhibitor is used to control postoperative pain and inflammation associated with orthopedic surgery?
Definition
Deracoxib
Term
What NSAID has the main side effects of vomiting, anorexia, diarrhea, and blood abnormalities?
Definition
Deracoxib
Term
How does Deramaxx and Previcox work?
Definition
Selectively inhibiting COX-2
Term
What NSAID is part of the oxicam group and acts by inhibiting COX-2, which inhibits prostaglandin synthesis and leukocyte infiltration in the inflamed area?
Definition
Meloxicam
Term
What NSAID is used to control musculoskeletal pain in dogs and is used as a post-op pain drug in cats?
Definition
Meloxicam
Term
What NSAID has the main side effects of anorexia, vomiting, diarrhea, and lethargy?
Definition
Meloxicam
Term
What NSAID is used for treating musculoskeletal pain, colic, shock, intervertebral disc disease, post-op pain, and parvovirus infections?
Definition
Flunixin meglumine
Term
What NSAID is an inhibitor of cycloxygenase and is labeled for horses and cattle?
Definition
Flunixin meglumine
Term
What are 2 side effects of Flunixin meglumine?
Definition
Rare anaphalaxis and localized pain/swelling
Term
What NSAID works by inactivating the superoxide radicals produced by inflammation?
Definition
Dimethyl sulfoxide
Term
What NSAID is used as a topical anti-inflammatory and as an IV treatment for CNS swelling?
Definition
Dimethyl sulfoxide
Term
What's the main side effect of Dimethyl sulfoxide?
Definition
Skin irritation
Term
What NSAID is used to treat pain/inflammation of osteoarthritis, fever, pain, and/or inflammation?
Definition
Firocoxib
Term
What are the 2 main side effects of firocoxib?
Definition
Vomiting and anorexia
Term
What drugs work by inhibiting phospholipase and strengthening cell membranes?
Definition
Glucocorticoids
Term
What drugs are also a corticosteroid type?
Definition
Glucocorticoids
Term
What corticosteroid drugs are used to treat inflammatory conditions, allergy responses, and systemic diseases?
Definition
Glucocorticoids
Term
What are 3 side effects of glucocorticoids?
Definition
polyuria, polydipsia, and polyphagia
Term
What is the duration of action of cortisone?
Definition
Short
Term
What is the duration of action of hydrocortisone?
Definition
Short
Term
What is the duration of action of methylprednisone?
Definition
Intermediate
Term
What is the duration of action of triamcinolone?
Definition
Intermediate
Term
What is the duration of action of dexamethasone?
Definition
Long
Term
What is the duration of action of betamethasone?
Definition
Long
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