Term
Cholinergic agonist OR parasympathomimetics |
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Definition
Drugs that stimulate the parasympathetic nervous system |
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Term
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Definition
the neurotransmitter located at the ganglions and the parasympathetic terminal nerve endings. Innervates cholinergic receptors in organs, tissues, and glands. |
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Definition
cholinergic receptor which stimulates smooth muscle and slows heart rate |
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Definition
cholinergic receptor which affects the skeletal muscles |
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Term
Direct-acting cholinergic agonists |
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Definition
act on receptors to activate a tissue response |
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Term
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Definition
an enzyme that is inhibited by indirect-acting cholinergic agonists |
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Term
Anticholinesterase (AChE) |
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Definition
Drugs that inhibit cholinesterase |
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Term
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Definition
Constriction of the pupils of the eyes. |
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Term
Direct-acting cholinergic agonists |
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Definition
Drugs that are selective to the muscarinic receptors but are nonspecific because the muscarinic receptors are located in the GI tract, glands, and heart. |
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Term
Indirect-acting cholinergic agonists |
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Definition
inhibit or inactivate the enzyme cholinesterase, permitting ACh to accumulate at the receptor sites. |
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Term
Anticholinergics OR Parasympatholytics OR Cholinergic blocking agents |
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Definition
Drugs that inhibit the actions of ACh by occupying the ACh receptors |
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Term
Cholinergic agonists, parasympathomimetics, cholinomimetics, cholinergic stimulants |
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Definition
Drugs that stimulate the parasympathetic nervous system are called ____(4 names) because the mimic the parasympathetic neurotransmitter ACh. |
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Term
Muscarinic receptors (stimulate smooth muscle and heart rate) Nicotinic receptors (affect skeletal muscles) |
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Definition
2 types of cholinergic receptors |
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Term
Direct-acting cholinergic agonists |
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Definition
Act on the receptors to activate a tissue response. |
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Term
Indirect-acting cholinergic agonists |
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Definition
Inhibit the action of the enzyme cholinesterase (ChE) |
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Term
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Definition
The leaking of fluid from a blood vessel into the surrounding tissues, as in the case of an infiltrated intravenous infusion. |
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Term
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Definition
The chemical attraction of a substance to lipid or fat molecules |
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Term
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Definition
Are alpha2 receptors inhibitory or stimulatory |
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Term
Beta-1 adrenergic receptors |
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Definition
Receptors that are located primarily in the heart |
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Term
Beta-2 adrenergic receptors |
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Definition
receptors that are located primarily on the smooth muscles of the bronchioles and blood vessels |
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Term
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Definition
A tumor that forms on the adrenal gland on top of the kidney and secretes norepinephrine, thus causing SNS stimulation. Alpha-blockers may prevent hypertension in patients who have this condition. |
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Term
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Definition
When drugs extravasate, or leak out of the blood vessel into the surround tissue, they cause vasoconstriction and ultimately _____________. |
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Definition
_____ can reverse the potent vasoconstriction and restore blood flow to the ischemic tissue, preventing necrosis. |
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Definition
Used for control of seizures |
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Term
False (Drugs with intrinsic sympathomimetic activity block beta-adrenergic receptors, but also partially stimulate them) |
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Definition
True or false: Drugs with intrinsic sympathomimetic activity stimulate beta-adrenergic receptors. |
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Term
Beta-1 receptors on the surface of the heart |
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Definition
Cardioselective beta1-blockers block which receptors and where are they located? |
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Term
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Definition
Production of glucose from glycogen -- catecholamines promote this. |
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Term
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Definition
Which blockers are considered to be cardioselective? |
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Term
False (beta-blockers protect the heart from being stimulated by catecholamines) |
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Definition
True or false: alpha-blockers protect the heart from being stimulated by catecholamines. |
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Term
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Definition
True or false: Because of their lipophilicity, some beta-blockers can easily gain entry into the central nervous system and are used to treat migraine headaches. |
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Term
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Definition
True or false: The patient's prescriber should be notified if the patient shows an increase of 2+ pounds in a 24 hour period or 5+ pounds within 1 week. |
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Term
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Definition
The nurse discovers that the intravenous infusion of a patient who has been receiving an intravenous vasopressor has infiltrated. The nurse will expect which drug to be used to reverse the effects of the vasopressor in the infiltrated area? A. Phentolamine B. prazosin (Minipress) C. ergotamine D. metoprolol (Lopressor) |
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Term
A. vasodilation, B. decreased blood pressure, and D. Constriction of the pupil |
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Definition
Adrenergic blockade at the alpha-adrenergic receptors leads to which of the following effects? A. Vasodilation B. Decreased blood pressure C. Increased blood pressure D. Constriction of the pupil E. Tachycardia |
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