Term
| what is the name for pain that is due to a stimulus which does not normally provoke pain |
|
Definition
|
|
Term
|
Definition
| increased resposne to stimulus which is normally painful |
|
|
Term
| what nerves carry sharp prickly pain |
|
Definition
|
|
Term
| what nerves carry dull, throbbing pain |
|
Definition
|
|
Term
| how do enkephalin releasing interneurons of the substantia geltinosa modify pain |
|
Definition
| release of enkephali acts to inhibit the release of substance P from the primary pain afferents and cause presynaptic inhibition. |
|
|
Term
| the most important spinal nerve tract for relaying pain and temperature is |
|
Definition
| lateral spinothalamic tract |
|
|
Term
| what are the signs and sx of complex regional pain syndrome |
|
Definition
1. spontaneous pain
2. hyperalgesia
3. allodynia
4. sweat gland activity
5. vasomotor abnormalities
6. active and passive motor disorders
7. sypmathetic dysfunction cna present as edema nd cyanosis. |
|
|
Term
| is inhibition of MAO-A or MAO-B responsible for treatment of depression |
|
Definition
|
|
Term
| What drugs are prohibited in the patient taking a monamine oxidase inhibitor |
|
Definition
1. Indirect acting sympathomimetic
2. TCA
3. opioids (especially demerol)
4. fluoxetine |
|
|
Term
| why do we no longer stop MAO-I prior to surgery |
|
Definition
| b/c stopping them will result in 2-3 weeks of refractory depression. |
|
|
Term
| what Sx will you see if you give demerol to a patient on a MAOI |
|
Definition
1. HTN
2. Seizures
3. Hypotension.
4. agitate
5. fever
6. coma
7. apnea |
|
|
Term
| which herbal causes the doubling of activity of the p450 system |
|
Definition
|
|
Term
| describe SX of serotonin like syndrome |
|
Definition
1. tachycardia
2. agitation
3. HTN
4. restlessness |
|
|
Term
| which herbal can produce or ponteniate the risk for serotonin syndrome |
|
Definition
|
|
Term
| three side effects of TCAs |
|
Definition
1. anticholinergic effects (dried mouth, blurred vision, tachycardia, urinary retention. slowed GI emptying, ileus, antichonlinergic delerium in elderly.
2. orthostatic hypotension
3. sedation |
|
|
Term
| TCAs and anesthesia drugs... |
|
Definition
| increase response to direct acting and indirect acting sympathomimmetics. |
|
|
Term
| Lithium toxicity occurs when plasma concentrations of lithium exceeds ____ |
|
Definition
| lithium plasma levels > 2 mEq/L can cause toxicity |
|
|
Term
| Sx of lithium toxicity are |
|
Definition
1. skeletal muscle weakness
2. ataxia
3. sedation
4. widening of the QRS complex
Severe toxicity
1. AV block
2. hypotension
3. seizures |
|
|
