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Pharmacology of MER
Metabolic/Endocrine/Reproductive
49
Medical
Graduate
04/19/2009

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Cards

Term
Regular Insulin
Definition
Short Acting
Hypoglycemia
Term
Insulin Lispro
Definition
Short acting
Lys-B28 and Pro-B29
Term
Aspart
Definition
Short Acting
Asp-B28
Term
Glulisine
Definition
Short acting Insulin
Term
NPH insulin
Definition
Intermediate acting
Bound to zinc and protamine
Term
Detemir
Definition
Intermediate acting
Bound to acyle chain
Term
Glargine
Definition
No Peak, Long acting insulin
Term
Glyburide
Definition
Sulfonylureas secretagog
Term
Glipizide
Definition
Sulfonurea secretatgog
Term
Repaglinide
Definition
Better than glyburide
Needs glucose to work
Term
Metformin
Definition
Blocks hepatic gluconeogenisis
Lactic Acidosis
Term
Pioglitazone
Definition
PPAR-gamma activate to increase insulin sensitivity
Term
Rosiglitazone
Definition
Activates PPAR
Term
Acarbose
Definition
Blocks brush border glucosidase

Flatulance Bloating
Term
miglitol
Definition
Same as acarbose
Term
Pramlintide
Definition
Amylin synthetic analoge. Hypoglycemic when used with insulin
Term
Exenatide
Definition
Incretin mimetic
TERATOGENIC
supresses glucagon slows empying
Term
Sitagliptin
Definition
Blocks catabolism of incretins
Term
Vildagliptin
Definition
Blocks catabolism of incretins
Term
Orlistat
Definition
inhibitor of gastic pancreatic lipase
Term
Sibutramine
Definition
Anorexic agent Brain uptake inhibitor
Term
Mifpristone
Definition
BLocks cortisol and progesterone receptors
Term
Aminoglutethimide
Definition
Blocks conversion of cholsterol to pregnenolone

SKIN RASH
Term
Ketoconazole
Definition
Blocks 11 and 17 hydroxylase

Liver enzymes
Term
Metyrapone
Definition
Blocks 11 hydroxylase
Term
Propylthiouracil
Definition
Blocks organification and T3-T4
Term
Methimazole
Definition
Blocks synthesis and inhibits coupling

No peripheral action
Term
Adlendronate
Definition
Bisphosphate
Term
Zolendronate
Definition
Bisphosphate
Term
Risedronate
Definition
Bisphosphate

Osteonecrosis of Jaw
Term
Raloxifene
Definition
antagonist in breast and uterus
Agonist in bone
Term
Leuprolide
Definition
non pulse GnHR
Term
Octreotide
Definition
Synthetic somatostatin
Term
Cabergoline
Definition
Better DA Agonist
Term
Sermorelin
Definition
Synthetic GHRH
Term
Dinoprost
Definition
E2 prostiglandin (2nd semester abortion)
Term
Tromethamine
Definition
2nd trimester abortion E2 prostiglandin
Term
Carboprost Tromethamin
Definition
Increases force and duration
15-methly PGH alph
Term
Clomifene Citrate
Definition
Estrogen partial agonist
Term
Gonadorelin acetate
Definition
Synthetic GnRH Pulsitile
Term
Menotropin
Definition
Purified HMG (LH and FSH like)
Term
hCG
Definition
LH
Term
Tamoxifen
Definition
Agonist at bone and uterus. Blocker at breast
Term
Norethindron
Definition
Synthetic progesteron
Term
Methyltestosterone
Definition
Oral
Term
Testosterone propionate
Definition
IM
Term
Oxandrolone
Definition
Steroid with more anabolic than androgen actions
Term
Finasteride
Definition
5-a-reductase inhibitor
Term
Flutamide
Definition
Receptor blocker
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