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Pharmacology Module II
Pharmacology Module II
13
Science
Graduate
06/02/2009

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Cards

Term
What are the major uses of eye drops?
Definition

1. Dry Eyes

2. Allergy/inflammation

3. Glaucoma

4. Infection

Term
For a topical application of eye drops, what should one drop be?
Definition
1 drop= 0.05 mL
Term
Which topical eye drug has a risk for airway obstruction?
Definition
Topical Timolol
Term
What do nasolacrimal occlusion causes?
Definition

1. A decrease systemic absorption (amt. in blood)

2. Increase drug absorption in eye

3. Helps decrease airway obstruction

Term
What can repeat doses of eye medication cause?
Definition
The washout effect
Term
Pro drug
Definition
Conversion of inactive drugs to active form
Term
What type of drug do you need to cross the cornea?
Definition
A lipid soluble one
Term
What are the effects of a prodrug?
Definition

1. Enhance corneal absorption

2. Prolong duration of action

3. Minimize systemic effects

4. Reduce ocular adverse effects

Term
What are some factors that affect ocular absorption?
Definition

1. VOlume

2. Surface tension

3. Osmolality

4. pH

5. Viscosity

6. Suspensions

Term
What are some drugs that can cause dry eyes?
Definition
Anticholinergics, antihistamines, beta-blockers, isotretinoin, oral contraceptives
Term
What are some ways that you can help reduce dry eye syndome?
Definition

1. Modify environmental habits

2. Artificial tears

3. Topical cyclosporine

4. Topical steroids

5. Secretagogues

6. Nutritional supplements

7. Punctal occlusion

 

Term
What are 2 therapeutic approaches to treating glaucoma?
Definition

1. Increase outflow of aqeous humor

2. Decrease formation of aqeous humor

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