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Digoxin - Digitalis Glycosides (Positive Inotropic Agent) MOA: Inhibit Na/K ATPase Pump CC: Steroid Glycoside DDIX: Macrolide Antibiotics |
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Milrinone - PDE3 Inhibitor (Positive Inotropic Agent) CC: Bipyridines |
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Quinidine - Class IA Sodium Channel Blocker Intermediate dissociation (Anti-arrythmic agent) Used for Ventricular arrythmias |
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Lidocaine- Class IB Sodium Channel Blocker Fast Dissociation (Anti-arrythmic agent) Used for Ventricular arrythmias |
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Propafenone- Class IC Sodium Channel Blocker Slow Dissociation (Anti-arrythmic) Very Potent with pro-arrythmic tendency |
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Propranonolol- Class II Beta Receptor Blocker (Anti-Arrythmic Agent) Reserved for Atrial tachycardia |
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Amiodarone - Class III Potassium Channel Blocker (Anti-Arrythmic Agent) Has broad activity |
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Sotalol - Class III Potassium Channel Blocker (Anti-arrythmic agent) IV |
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Diltiazem - Class IV Calcium Channel Blocker (Anti-Arrythmic) Can be pro-arrythmic and used to treat supraventricular arrythmias |
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Verapamil - Class IV Calcium Channel Blocker (Anti-Arrythmic) Can be pro-arrythmic and used to treat supraventricular arrythmias |
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Fluticasone - Steroid (Anti-inflammatory) agonist at glucocorticoid receptor for inhalation |
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Montelukast - Leukotriene Inhibitor (Anti-inflammatory) Also used for allergy |
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Cromolyn - Mast cell stabilizer (Anti-inflammatory) CC: Chromones Chronic therapy and its safe but less effective with QID dosing |
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Ipratropium - Anticholinergic (Bronchodilator) MOA: Muscarinic receptor antagonist CC: Quaternary amino alcohol esters for COPD |
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Tiotropium - Anticholinergic (Bronchodilator) MOA: Muscarinic receptor antagonist CC: Quaternary amino alcohol esters for COPD |
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Albuterol - Sympathomimetic (Bronchodilator) SABA MOA: Agonist at beta adrenergic receptors CC: Substituted beta hydroxy phenethylamines- Selectivity increase with steric bulk on N (Salicyl phenyl alcohol> Resorcinol > Catechol) |
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Formeterol - Sympathomimetic (Bronchodilator) MOA: Agonist at beta adrenergic receptors LABA CC: Substituted beta hydroxy phenethylamines- Increased resistance to metabolism byu COMPT due to larger molecular size and Increased lipophilicity |
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Salmeterol - Sympathomimetic (Bronchodilator) MOA: Agonist at beta adrenergic receptors LABA CC: Substituted beta hydroxy phenethylamines- Increased resistance to metabolism byu COMPT due to larger molecular size and Increased lipophilicity |
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Theophylline - Xanthines (Bronchodilator) MOA: Inhibit phosphodiesterase non specifically and act at adenosine receptors (anti-inflammatory) NOTE: Narrow therapeutic range |
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