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Pharmacology Final
Nursing
66
Nursing
Undergraduate 2
05/02/2011

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Term
ACE inhibitors
Definition

SE: Angioedema, 1st dose phenomenon

(give first dose at night),

cough

(change med to an ARB… –sartan)

hyperkalemia, syncope, change in taste

Term
ACLYCLOVIR (zovirax) –
Definition

Antiviral for herpesvirus Caution: renal failure--> use lower dose administer for at least 1 hr to prevent renal tublar damage!!!!

Term
ACTIVASE (Alteplase)
Definition

• BEST IF ADMINISTERED 3-6 HOURS AFTER ONSET OF SYMPTOMS! (So first thing to ask pt: “when did symptoms first start?”)

Term
ALBUTEROL (Proventil) –
Definition

First line asthma use!Prevention, ongoing Tachycardia , drymouth, HA , nervousness, restlessness, paradoxical bronchospasms, throat irritaion rinse mouth out with water and spit out to avoid swallowing med

Term
ALLEGRA (Fexofenadine) –
Definition
Dont eat with grapefruit , APPLE or ORANGE
Term
Symmetrel
Definition
Use: Prevention 70% patients for influenza A
Cont: sucidal ideation
Se: antiparkinsonian effects
Term
AMPICILLIN (principen) –
Definition
Use:Enterococci, E.coli, proteus mirabilis, Neisseria gonorrhea, H. influenza
Contra: Allergy to any drug in the penicillin class
S/e: pseudomembranous colitis (belly cramps, bloody stool= flame colon-stop drug)
Take on empty belly w/ 8 0z h20
decreased absorbtion w/ food
monitor 30 min after parenteral
DO NOT treat diarrhea w/ OTC
Term
ANCEF (cefazolin sodium) –
Definition
• USE: Infections of the respiratory tract, urinary tract, skin structures, biliary tract, bones, and joints, genital infections, septicemia, and endocarditis. Infection prophylaxis in surgical patients
• Caution: Hypersensitivity to penicillins
Term
APRESOLINE (Hydralazine) –
Definition
Administer 2-4 times/ day with food to increase bioavailablity
Rebound HTN
this drug decreases peripheral resistance, increases after load and increases cardiac output
Term
ARALEN (Chloroquine) –
Definition
Meds for malaria must be started before arrival to the endemic area nad continue throughout and 4-6 weeks after leaving area
s/e: cardiotoxicity
dd: antacids, laxatives must not use w/in 4 hrs
Urine may be rusty brown or yellow
wear dark glassess in sunligh or bright
ECG b4 and after treatment
Term
ASPIRIN (acetylsalicylic acid) –
Definition
Use:Pain/Fever/antiplatelet
GI Bleeding
Children under 18
Term
ATROVENT (Ipratropium) –
Definition
Bronchodilator; anticholonigeric
not for acute asthma
2 puffs 1 min. w/ albuterol wait 5 min
Term
AZATHIOPRINE (azasan, imuran) –
Definition
Use: prophylaxis of kidney transplant rejection
s/e: Bone marrow supression (bleeding, SOB and infection
No vaccines, avoid large crowds, use birthcontrol 4 months b4 and after.
Term
CELEBREX (celecoxib)
Definition
Use: Arthritis
s/e:GI bleeding/abdominal pain
expensive drug but is only 1 day dosage
Term
CIPRO (ciprofloxacin HCI) –
Definition
Use: Bacteral dna replication inhib. (floroquinolone)
Use: treatment of UTI---NOT PROPHALXSIS, Gonorrhea
Teach: drink 2-3 L of fluid per day
Term
CROMOLYN (Intal) –
Definition
Safe to use on children/safest of all asthma meds
If aerosol spray such as Albuterol is used in addition use bronchodilator first
Term
CYCLOSPORIN (sandimmune) –
Definition
Use: Organ tissue transplants
No grapefruit juice increase levels by 200%
Stay away from crowds!
Term
Calcium channel blockers
Definition
•Class of choice for vasospastic angina
Term
DAPSONE (DDS) –
Definition
Use: leprae infections
Photosensitivity
Reddish-brown discoloration of skin, cornea, conjuctiva and body fluids
Minimize the use of soap and rinse thouroughly.
Term
DIAMOX (Acetazolamide)
Definition
Motion sickness, altitude sickness
Check for Symptoms of mild or moderate metabolic acidios and potassium loss, increase risk in early therapy
Adequate fluid intake to decrease the risk of kidney stones
Term
EPIVIR (lamivudine) –
Definition
caution: renal impairment should be monitored close for change in urinary values
se: can cause unusal type of liver abonomality called lactic acidosis and hepatomegaly with steatosis
nursing: monitor blood counts 2-3 hrs
teach: at least 4 weeks may be needed before any improvment in symptoms are noted
Term
ERYTHROMYCIN –
Definition
Use: Alternative for patients allergic to PCN, Anaphylaxis, Hearing loss (ototoxicity), vertigo, dizziness, cardiotoxicity with risk for torsades de pointes.
• Give oral medicine with 8 ounces of water on an empty stomach 1 hour before or 3 hours after eating; Give enteric coated tablets without regard to meal; Report any ototoxic effects
Caution: Grapefruit
Anaphylaxis, Hearing loss (ototoxicity), vertigo, dizziness, cardiotoxicity with risk for torsades de pointes
Term
EZETIMIBE
Definition
Antilipidmeic
statins MUST be admin with this
Term
FANSIDAR
Definition
Use: toxoplasmosis, Malaria
Cont: Patients w/ Sulfer allergy
S/E: Folic acid deficiency; avoid sun
DO NOT USE FOLIC ACID SUPPLEMENTS
Term
FLAGYL
Definition
uSE: Trich
Cont: Bone Marrow Suppression
Darkens urine = toxicity
Term
FLORINEF (Fludrocortisones) –
Definition
Mineralcorticoid
s/e: sodium and fluid retention biggest concern
cont: systemic fungal infection
Term
Diflucan
Definition
(-AZOLE)Infections by Candida albicans
sse: Hepatoxic, Steven J. in immunosupporessed
Term
FUNGIZONE (amphotericin B deoxycholate) –
Definition
Use: Severe systemic mycoses, PROPHALATIC antifungal
cont: Bun >40, Serum Creatine >3
monitor these b/c hepatox
Admin IV slow 2-6hrs
Premed with antiemetic
Assess for ototoxicity
Term
GENTAMICIN (garamycin) –
Definition
•Now mostly used for TB
Increased risk of ototoxicity with other drugs affecting the 8th cranial nerve
• Draw blood for peak serum gentamicin concentration 30 minutes to 1 hour after IM; 30 minutes after a 30-60 minute IV infusion
Avoid direct exposure to sunlight; Wear protective clothing; Sunglasses, and sunscreen
Term
HCTZ (Hydorcholorthiazide) –
Definition
Sodium and Potassium restrictions
Term
HEPARIN
Definition
• Antagonist: Protamine sulfate IV (1 mg for every 100 units of heparin)
Term
HEPATITIS B VACCINE (Engerix – B) –
Definition
Use: immunization
made from yeast cells
check for egg allergy
Term
HYDROCORTISONE (Aeroseb-HC) –
Definition
For Inflammation; asthma
nr: d/c gradually in client w/ longer than 2 weeks therapy, baseline weight, check levels of stress
Term
IBUPROFEN (advi, Motrin)
Definition
Use: Fever/Pain
s/e:GI bleeding
Can take with food or Milk=prevention belly issues
Term
INTRON A (INTERFERON Alfa-2B)
Definition
use:Cancer melonomia, Leukemia
S/e: Flu like symptoms
No ETOH at all= dehydration
Term
ISONIZID (INH) –
Definition
Term
KETAMIN (Ketalar) (aka: “Special K”)
Definition
Anethesia- safe for children
produces a feeling of seperation from the enviorment
Term
LASIX (Furosemide) –
Definition
Loop diurect
do not take with digoxin
ability to remove large amounts of edema from body in short amount of time
se: greatest concern is extensive fluid loss and electrolyte imbalance.
Dehydration
must have 30 ml urine output
calf pain
ototoxicity
hypokalemia
Term
LISINOPRIL (Prinivil) –
Definition
cough angeoadema
Term
METHYLDOPA (Aldomet) –
Definition
Antihypertensive
Use: HTN that has not responded adequaltley to safer antihypertensives
Nursing: Minimize day time seation by take medications at bed time
Term
NIACIN (nictonic acid)
Definition
SE: hot flashes- give asprin 30 min prior
Term
NITROFURANTOIN (furadantin)
Definition
Use: PROPHYLLAXIS /recurrent UTI's
Teach: inform client of urine being discolored and take medication for full treatment
Term
NITROPRESS (Nitropruside Sodium) –
Definition
Use: Life threatening HTN
se: skin flusing
Nursing: titrate.
check drug solution periodically to protect from light
Term
NITROUS OXIDE
Definition
Consent befor they get the gas-
NPO pre op
Term
NOVOCAINE (Procaine) –
Definition
Do not consume hot foods, chew gum after dental procedures until sensation returns
hypotension is the most common and severe complication
Term
NYSTATIN (Mycostatin) –
Definition
Candida infection in mouth, vagina, skin intestines
Teach: Apply to treat thrush meals and at bedtime.
Troches take 30 min to dissolive and not food or drink for 30 min after
Vulvovagina can take 2 weeks and continue during menustration
Term
ORTHOCLONE (muromonab – CD3) –
Definition
Use: Prevent acute transplant rejection of solid organs like liver
s/e: cytokine release syndrome (fever chills tremor) --> give steroid or antihistimine before treatment.
Do not give with active infection
Term
OSMITROL (Mannitol) –
Definition
Used for emergencies!
Decreases ICP-head trauma= decrease in pressure
Nursing: Most effective if given bolus instead of continous infusion.
administer with filter in IV tube or use filter needle when drawing to prevent microscopic crystals
Term
PENICILLIN G –
Definition
Use: Gram + bacteria, endocarditis
Cont: Heart Failure (sodium salt) allergies
S/E: anaphylaxis--> edema of mouth, tounge pharynx
When giving IM stay w/ pt for 20 min (allergy check)
Term
PREDNISONE (Meticorten) –
Definition
Anti inflammator and Immunosuppressnat
Irritability and mood swings
Term
PRIMAXIN (imipenem-cilastatin) –
Definition
Use: Broad spectrum alternative to PCN; most gram + and Gram -
Determine sodium content for sodium restricted patients
Term
PROCAINAMIDE (Pronestyl)
Definition
• USE: atrial and ventricular dysrhythmias
• DRUG OF LAST CHOICE B/C OF TOXICITY
Term
PROLEUKIN (aldesleukin)
Definition
Use: Mestac renal carcinmoa
S/e: Capillary leak syndrom--> listen to lungs if you hear wet cracks = this.
Term
PROSCAR (Finasteride) –
Definition
use: BPH and H irsuitism in femals
The max benifit from the drus is achieved 6-12 months
Improvments will last for as long as the med is taken after that amount of time
X
Term
QUESTRAN (cholestyramine)
Definition
Antihyperlipidemic; bile acid sequestrant
Causes: Constipation
Tri >400 do not give
Term
RETROVIR (zidovudine) –
Definition
Use: HIV- PROPHYLACTIC in health care works; decrease vertical transmission
administer on empty belly w/ water only
start at 14-34 weeks in prego hiv
iv infusion during labor and infacnt will have to have oral med for first 6 weeks of life
Term
RHOGAM (Rh0[D] immune globulin) –
Definition
passive immunity
within 72 hours
• MOA: Suppression of the immune response of Rh-mothers to Rh+ fetuses
Term
SPIRONOLACTION (Aldactone) –
Definition
SE; Hyperkalemia >5 meq
Term
TESTOSTERONE (Androgen) –
Definition
Prego: X
Use:Hypogonadism, Androgen responsive to breast cancer
Term
TETRACYCLINE (Sumycin) –
Definition
Use: Gram + gram - bacteria, Chlamydia
Widespread resistances has happened
DNA <8 yrs age
Discoloration of teeth/photsensisitvity
Admin w/ full glass of water on empty stomach.Skin may look yellow under blk light.
takes up to 12 weeks
Term
Bactrim
Definition
Use: UTI from e. coli
Cont: sulfa or thiazide diuretics
S/e: crystalluria, photosensitivity
encourge lots and lots of water~
Term
TYLENOL (acetaminophen) –
Definition
Use: Fever/pain
Caution: Hepatic
S/E: hepatic failure
Antidote: Mucomyst
Term
VANCOMYCIN (vancocin) –
Definition
Use:severe infections resistant to safer antibiotics
Caution: history of hearing loss
assess baseline hearing
S/E: Red Man syndrome (flushing, hypotension, tachycardia)- infuse over 60 min slow to avoid
Note oliguria or cloudy pink urine=nephrotoxicity.
Term
VERMOX (Mebendazole) –
Definition
Uses: Round worm, pin worm parasites
teach: good hygine, hand washing changing of towels and undergarments.
TREAT ENTIRE FAMILY
report fatigue and sever diarrhea fever or chills
chew and take w/ fatty meals
Term
Digoxin
Definition
Heart failure
increase contract/decrease HR
se: dysrythmias
0.5-1
toxic more than 2
n/v = toxicity also yellow green halos
<60 apical dont give
check k+ levels
client should be on k+ sparing drug
Term
Losartan
Definition
Sodium and potassium restrictions
Antihypertensive
causes nasal congestion
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