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vitamin/mineral drug list: |
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- vit. A, B, C, D, E, K - tretinoin - calcium - ascorbic acid - nicotinamide - nicotinic acid - folic acid - cyanocobalamin |
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- melatonin - ma-huang - St. John's wort - ginkgo - ginseng - saw palmetto - dehydroepiandrosterone |
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carbon monoxide, amphetamines, marijuana, LSD, caustic agents (acids & bases), morphine, meperidine, atropine, barbiturates, benzodiazepines, ethanol, methanol, neuroleptics (phenothiazines), kerosene, organophosphates, salicylates, acetaminophen, cocaine, PCP, tricyclic antidepressants, methaqualone, digoxin, phenytoin, theophylline, cyanide, heavy metals (e.g. arsenic, iron, lead, copper, mercury), oxalate |
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: ipecac, charcoal, n-acetylcysteine, BAL (dimercaprol), flumazenil, glucagons, hyperbaric oxygen, vitamin K, nitrites, digoxin-specific Fab fragments, ethanol, fomepizole, protamine, deferoxamine, pyridoxine, naloxone, methylene blue, atropine, pralidoxime, hemodialysis, hemoperfusion, alkaline diuresis |
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- Vit. C (ascorbic acid) - Nicotinic acid and nicotinamide (derivatives of vitamin B3) - folic acid - cyanocobalamin (vit. B12) |
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Vitamin C (ascorbic acid) is necessary in body to form what? |
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- collagen in bones, cartilage, muscle, and blood vessels |
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Nicotinic acid and nicotinamide are ___ __ __. |
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Deficiency of vitamin B3 (nicotinic acid/nicotinamide): |
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- Pellegra: skin disease, diarrhea, dementia, depression |
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Overdose of vitamin B3 (nicotinic acid/nicotinamide): |
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Definition
- liver toxicity - increased liver enzyme levels in blood - jaundice - ascites - liver failure |
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Folic acid (form of vitamin B)deficiency: |
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- risk of fetus developing neural tube defects (spina bifida) - Megaloblastic and Macrocytic anemias |
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- very high doses> CNS side effects |
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Cyanocobalamin is vitamin ___. |
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Cyanocobalamin (vit B12) deficiency helps maintain healthy __ __, __ __ __, and is also needed to make ___. |
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- nerve cells - red blood cells - DNA |
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Deficiency of cyanocobalamin (vit B12): |
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Vitamin A is required for many biological procedures like __ and __ __. |
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vision and cellular growth |
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- xeropthalmia (dry eye) - night blindness - total blindness - skin disorders |
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- acne - certain leukemias - measles - malaria - retiniis pigmentosa |
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- hypervitaminosis A - infants with acute toxicity have bulging fontanels - adults get brain tumor like symptoms - severe toxicity: eye damage, high calcium levels, liver damage |
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Vitamin D aids in absorption of ___, helping to from and maintain strong bones. |
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- rickets in children - osteomalacia in adults |
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Vitamin D is used for TREATMENT OF: - hypophosphatemia - hypocalcemia - hyperparathyroidism - psoriasis - osteomalacia - renal osteodystrophy |
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- hypercalcemia - excess bone loss |
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Vitamin E acts as an ___, acts through ___, and has an __ __. |
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- antioxidant - immunomodulation - antiplatelet effect |
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- profoundly effects CNS> ataxia and peripheral neuropathy |
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Vitamin E uses are controversial |
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increase risk of bleeding problems |
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Vitamin K is necessary for __ __. |
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- defective blood clotting - increased bleeding |
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Vitamin K used for treatment of: - hemorrhagic disease of newborn - warfarin reversal |
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NCCAM: branch of FDA, look at literature out there and determine if they are good studies and if the herbals are good to use or not. |
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Black cohosh claimed uses: |
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- hot flashes - night sweats - vaginal dryness - other menopause symptoms
STUDIES ARE MIXED AND LESS THAN 6 MONTHS LONG |
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Black cohosh side effects: |
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- HA - gastric complaints - weight problems - no reports of interactions with prescriptions |
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Contraindication for black cohosh: |
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- patient at risk for breast cancer should not take black cohosh |
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- Monks in Middle Ages used it to decrease sexual desire - PMS - menopausal symptoms - infertility - acne
DATA SHOWS SOME BENEFIT FOR USE IN PMS, BREAST PAIN, AND INFERTILITY IN POORLY DESIGNED STUDIES. MORE DATA NEEDED. |
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OBGYNS use ___ to treat infertility and PMS symptoms. But be careful b/c it interacts with __ __ and other hormones. |
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- chasteberry - birth control pills |
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- common colds - flu - URIs
NO STUDY HAS SHOWN ANY EVIDENCE OF IT WORKING THOUGH MORE RESEARCH IS UNDERWAY REGARDING EFFECTIVENESS IN URI. |
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- asthma - anaphylaxis - rashes |
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___ is related to plants in the daisy family including ragweed. So people with allergies should be careful. |
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Ephedra aka __ __ or ___ ___. |
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- weight loss - colds - fever - flu - headaches - asthma - wheezing - nasal congestion |
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Ephedra increases risk of __, __, and ___ problems, as well as __ __ __ and __. |
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- heart, psychiatric, and gastrointestinal problems - high blood pressure and stroke |
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nausea, anxiety, headache, psychosis, kidney stones, tremors, dry mouth, irregular heart rhythms, heart damage, high blood pressure, restlessness, sleep problems, irritation of the stomach, and increased urination
NO LONGER FDA APPROVED AS OF 2004 |
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With fiber/flax seed the benefits outweigh the risks. |
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Flax seed. Take 1 tablespoon per day. This is the largest source __, largest source of ___ __, and largest source of __ __. |
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- fiber - omega 3s - plant estrogen |
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Data on flax and fiber show that it is an effective __. There is mixed data on it lowering ___ and preventing __ __. No side effects. |
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- effective laxative - lowering cholesterol and preventing heart disease |
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1 tablespoon flax seed= 9 grams fiber |
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Flax has omega 3 in form of ___ while fish oil has omega 3 in form of ___. |
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- tmt of high cholesterol - tmt of hypertension - heart disease - stomach cancer
DATA SHOWS THAT IT DOES NOT WORK |
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breath and body odor, heartburn, upset stomach, and allergic reactions, acts like a blood thinner similar to ASA, interferes with some anti-HIV meds |
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Garlic acts like a ___ __ like ASA, so it needs to be stopped before surgery. It also interferes with __ meds. |
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- stomach aches - nausea - diarrhea
safely relieve pregnancy-related nausea and vomiting; studies are mixed on effect on chemo-induced nausea |
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- improve memory - prevent Alzheimer's disease and other dementia - may also reduce symptoms of claudication
studies are promising but more needed |
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Ginko Biloba side effects: |
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- boost immune system - improves mental and physical performance - tmt of erectile dysfunction - menopause symptoms - lower blood glucose
Data shows it may be effective at lowering blood glucose, but no data for other claims. |
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- headaches - sleep problems - GI problems - caution in patients with Diabetes |
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- osteoarthritis tmt
good evidence to support the use of glucosamine sulfate in the treatment of mild-to-moderate knee osteoarthritis |
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Glucosamine side effects: |
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- upset stomach - drowsiness - insomnia - headache - skin reactions - sun sensitivity - nail toughening - may increase bleeding risk |
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Kava (aka kava pepper) uses: |
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- anxiety - insomnia - menopausal symptoms
Some evidence shows may be effecive against anxiety, but FDA warns it can cause liver toxicity |
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What herb is supposed to help with anxiety but may cause liver toxicity? |
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- liver damage/hepatitis/liver failure - dystonia - may interact with Parkinson's drugs |
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what herb used to treat anxiety may interact with Parkinson's drugs: |
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Noni is aka ___, __ __, __ __, and __ __. |
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- Morinda - Indian mulberry - Hog apple - Canary wood |
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- joint pain - skin conditions - cardiovascular disease - diabetes
Data has shown antioxidant, immune-stimulating, and tumor-fighting properties, but not well studied; |
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- high potassium (so not good for patients with liver disease) - liver disease |
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kidney disease b/c causes high potassium |
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ALA omega 3s are in __, __,__, and __ __. |
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flax soy walnuts vegetable oils |
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EPA and DHA omega 3s are in __ and __. |
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In pregnancy you need ____ by third trimester to help brain development. |
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- lower TGs - reduce risk of death - reduce risk of heart attack - used to treat abnormal heart rhythms - reduce risk of stroke - lowers blood pressure slightly |
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- fishy taste - increased bleeding at high doses - potentially harmful contaminants such as dioxins, methylmercury, and polychlorinated biphenyls (PCBs) are found in some species of fish |
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- PMS - menopausal symptoms - eczema
data not very supportive |
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side effects of primrose oil: |
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Red rice yeast is aka ___. One of these __ __ is a potent inhibitor of ___ ___ __ and is aka __ or ___. |
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- Monacolins - Monacolin K - HMG-CoA reductase - Mevinolin - Lovastatin |
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- cholesterol lowering agent
supportive evidence for TG lowering and LDL lowering properties; no strong evidence exists for cardiovascular benefits or diabetes |
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Side effects of Red Rice Yeast: |
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similar to those for the prescription drug lovastatin (MevacorĀ®) heartburn, gas, bloating, muscle pain or damage, dizziness, asthma, and kidney problems are possible; people with liver disease should not use red yeast products; may increase the risk of bleeding. Warning |
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Red rice yeast is a precursor to the __ drugs. |
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Saw Palmetto aka __ __ __ __ aka __ __. |
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- American dwarf palm tree - Cabbage palm |
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- urinary symptoms associated with enlarged prostate - chronic pelvic pain - bladder disorders - decreased sex drive - hair loss - hormone imbalances
not enough scientific evidence to support the use of saw palmetto for reducing the size of an enlarged prostate or for any other conditions |
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Saw palmetto side effects: |
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- stomach discomfort - tender breasts - decreased libido |
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- depression - anxiety - sleep disorders
some effect shown compared to placebo in mild depressive disorder but more well-developed studies are needed and there are safety concerns |
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St Johns Wort interacts with __ __ __. |
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St. John's wort side effects: |
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- increased sensitivity to sunlight - anxiety - dry mouth - dizziness - GI symptoms - fatigue - headache - sexual dysfunction - tons of drug interactions including birth control |
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