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This equation allows you to calculate an oral or intravenous loading dose needed to achieve a desired target [ ]. This also allows you to calc. how much additional drug should be administered to raise an existing drug concentration to a more desirable target [ ]. |
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Equation for Loading Dose |
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Volume of distribution. This is a unique constant for each drug |
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What does S represent in LD |
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Fraction of active drug present w/in the salt. |
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How do you calculate S if the drug is not administered as a salt? |
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What equation allows you to determine what [ ] will be achieved following administration of an oral or IV loading dose. |
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Peak Concentration following a single dose. |
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What is the equation for peak concentration following a single dose |
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What is the equation
ΔCp = F x S x LD
Vd
used for?
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To calculate the peak concentration following a single dose.
*notice that this equation is simply a rearrangement of the LD equation. |
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