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Pharmacology and the Nursing Process (Lilley 6ed.)
Ch. 46 Immunizing Drugs and Biochemical Terrorism
25
Nursing
Not Applicable
09/12/2012

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Term
Active Immunization
Definition
A type of immunization that causes development of a complete and long-lasting immunity to a certain infection through exposure of the body to the associated disease antigen; it can be natural active immunization (i.e., having the disease) or artificial active immunization (i.e., receiving a vaccine or toxoid)
Term
Active Immunizing Drugs
Definition
Toxoids or vaccines that are administered to a host (human or animal) to stimulate host production of antibodies
Term
Antibodies
Definition
immunoglobulin molecules that have an antigen-specific amino acid sequence and are synthesized by the humoral immune system (B cells) in response to exposure to a specific antigen (foreign substance). Their purpose is to attack and destroy molecules of this antigen.
Term
Antibody Titer
Definition
the amount of an antibody needed to react with and neutralize a given volume or amount of a specific antigen
Term
Antigens
Definition
substances, usually proteins and foreign to a host (human or animal), that that stimulate the host to produce antibodies and that react specifically with those antibodies
Term
Antiserum
Definition
a serum that contains antibodies
Term
Antitoxin
Definition
an antiserum against a toxin (or toxoid)
Term
Antivenin
Definition
an antiserum against a venom (poison produced by an animal) used to treat humans or other animals that have been envenomed
Term
Biological Antimicrobial Drugs
Definition
substances of biological origin used to prevent, treat , or cure infectious diseases
Term
Bioterrorism
Definition
the use of infectious biological or chemical agents as weapons for human destruction
Term
Booster Shot
Definition
A repeat dose of an antigen, such as a vaccine or toxoid, which is usually administered in an amount smaller than that used in teh original immunization
Term
Cell-mediated Immune System
Definition
the immune response that is mediated by T cells (as opposed to B cells, which produce antibodies)
Term
Herd Immunity
Definition
resistance to a disease on the part of an entire community or population because a large proportion of its membersare immune to the disease
Term
Immune Response
Definition
a cascade of biochemical events that occurs in response to entry into the body of an antigen (foreign substance)
Term
Immunization
Definition
the induction of immunity by administration of a vaccine or toxoid (active immunization) or antiserum (passive immunization)
Term
Immunizing Biologics
Definition
toxoids, vaccines, or immunoglobulins that are targeted against specific infectious microorganisms or toxins
Term
Immunoglobulins
Definition
glycoproteins synthesized and used by the humoral immune system (B cells) to attack and kill all substances foreign to the body
Term
Passive Immunization
Definition
a type of immunization in which immunity to infection is conferred by bypassing the host's immune system and injecting a person with antiserum or concentrated antibodies obtained from other humans or animals that directly give the host the means to fight off an invading microorganism
Term
Passive Immunizing Drugs
Definition
drugs containg antibodies or antitoxins that can kill or inactivate pathogens by binding to the associated antigens
Term
Recombinant
Definition
relating to or containing a combination of genetic material from two or more organisms
Term
Reticuloendothelial System
Definition
specialized cells located in the liver, spleen, lymphatics, and bone marrow that remove miscellaneous particles from the circulation, such as aging antibody molecules
Term
Toxin
Definition
any poison produced by a plant, animal, or microorganism that is highly toxic to other living organisms
Term
Toxoids
Definition
bacterial exotoxins that are modified or inactivated (by chemicals or heat) so that they are no longer toxic but can still bind to host B cells to stimulate the formation of antitoxin
Term
Vaccines
Definition
Suspensions of live, attenuated, or killed microorganisms that can promote an artificially induced active immunity against a particular microorganism
Term
Venom
Definition
a poison that is secreted by an animal or insect
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