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Pharmacology 2
Pharm Unit 9 Section 1 TCAT
56
Pharmacology
Undergraduate 3
03/06/2014

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Cards

Term
What are the risk factors of metabolic syndrome?
Definition
Type 2 diabetes,Obesity,Hyperlipidemia ,Hypertension
Term
Atherosclerosis
Definition
fatty deposits on inner walls or arteries
Term
Treats hyperlipidemia?
Definition
HMG-CoA reductase inhibitors,B3(Niacin),Bile Acid binding,Fibric Acid derivatives,Ezetimibe,Omega-3 fatty acids
Term
atorvastatin (Lipitor)
Definition
HMG-CoA reductase inhibitors
Term
fluvastatin (Lescol)
Definition
HMG-CoA reductase inhibitors
Term
simvustatin (Zocor)
Definition
HMG-CoA reductase inhibitors
Term
pravastatin (Pravachol)
Definition
HMG-CoA reductase inhibitors
Term
lovastatin (Mevacor)
Definition
HMG-CoA reductase inhibitors
Term
rosuvastatin (Crestor)
Definition
HMG-CoA reductase inhibitors
Term
When are HMG-CoA reductase inhibitors best given?
Definition
at hour of sleep
Term
Who should not take HMG-CoA reductase inhibitors?
Definition
pregnant females,nursing mothers,patients with liver disease
Term
What drug should not be taken with grapefruit products?
Definition
HMG-CoA reductase inhibitors
Term
B3(Niacin)
Definition
decreases LDL and triglyceride production
Term
What are the side-effects of B3 (Niacin)?
Definition
flushing,itching rash,tingling
Term
Bile Acid binding
Definition
treats hyperlipidemia
Term
cholestyramine (Questran)
Definition
Bile Acid Binding
Term
What are the side-effects of Bile Acid binding drugs?
Definition
may interfere with absorption of fat-soluble vitamins
Term
Fibric Acid derivatives
Definition
reduces triglycerides and LDL-C levels, lowers cholestrol levels
Term
gemfibriozil (Lopid)
Definition
Fibric Acid derivative
Term
ezetimibe (Zetia)
Definition
blocks absorption of cholestrol from small intestine
Term
Side-effects of ezetimibe?
Definition
abdominal bloating,nausea,diarrhea
Term
Omega-3 fatty acids (fish oils)
Definition
reduce the synthesis of triglycerides in the liver
Term
Lovaza
Definition
Omega-3 fatty acids
Term
Risk factors of hypertension?
Definition
smoking,obesity,sedentary lifestyles,diet (high fat),diabetes,family history,ageing process
Term
Whats the first line treatment of hypertension?
Definition
thiazide diuretics,beta blockers,ACE inhibitors
Term
the "prils"
Definition
ACE inhibitors
Term
What can hypertensives cause and what must the patient do when first starting these drugs?
Definition
Postural hypotension,remind patients to change positions slowly
Term
the "sartans"
Definition
Angiotension 2 Receptor Antagonists (ARB's)
Term
end in "olol"
Definition
Beta Blockers
Term
What are beta blockers contraindicated in?
Definition
bronchoconstrictive disorders,peripheral vascular disease and not drug of choice for type one diabetes mellitus
Term
Calcium Ion antagonists
Definition
treat angina,arrhythmias (commonly prescribed antihypertensives)
Term
What do HMG-CoA reductase inhibitors treat?
Definition
hyperlipidemia
Term
What are the major risk factors of hypertension?
Definition
smoking,obesity,sedentary lifestyles,high fat diet,diabetes,family history,ageing process
Term
nifedipine (Procardia)
Definition
Calcium ion antagonist
Term
amlodipine (Norvasc)
Definition
Calcium ion antagonist
Term
clonidine(Catapres)
Definition
Centraly acting agents (po and patch)
Term
What is sometimes used in drug withdrawal?
Definition
Centrally acting agents
Term
Side-effects of Centrally acting agents?
Definition
sedation,dizziness,dry mouth
Term
Side-effects of ACE inhibitors?
Definition
cough,headache,dizziness,fatique
Term
What drug can cause gingival hyperplasia?
Definition
diltiazem
Term
What do you have to watch for Beta blockers?
Definition
if apical is less than 60 or systolic is less than 100
Term
What are the names of the Diuretics?
Definition
Loop,thiazide,potassium sparing and mixed potassium sparing/potassium wasting
Term
furosemide (Lasix)
Definition
Loop diuretic
Term
bumametanide (Bumex)
Definition
Loop diuretic
Term
hydrochlorothiazide (HCTZ)
Definition
Thiazide diuretic
Term
chlorothiazide (Duril)
Definition
Thiazide diuretic
Term
chlorthalidone (Hygroton)
Definition
Thiazide diuretic
Term
metolazone (Zaroxolyn)
Definition
Thiazide diuretic
Term
spironolactone (Aldactone)
Definition
Potassium sparing diuretic
Term
triamterene (Dyrenium)
Definition
Potassium sparing diuretic
Term
triamterene & hydrocholothiazide (Maxide) (Dyazide)
Definition
Mixed potassium sparing/wasting
Term
What are other uses for diuretics?
Definition
peripheral and pulmonary edema,renal disease,liver disorder,cerebral edema
Term
What is the best way to measure diuresis?
Definition
daily weights and I&O
Term
How is Lasix given?
Definition
slow push over two min. (20mg/min)
too rapid infusion causes ototoxicity
Term
What is a common side-effect of thiazide and loop diuretics?
Definition
hyperglycemia
Term
What type of foods must you take with Potassium sparing/wasting drugs?
Definition
oranges,bananas,melons,tomatoes,potatoes
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