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Definition
| ability to accumulate and store drugs after absorption; attraction between a drug and a receptor |
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| drug that produces the same type of response as the endogenous substance [hormone or neurotransmitter]; the drug mimics the effect of the endogenous regulatory molecule |
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| drug will occupy a receptor and prevent the endogenous substance from acting on the receptor; also called a receptor blocker; often compete with agonist for receptor binding site, preventing agonist from binding to receptor |
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Definition
| how a drug produces its effect in the body; it is also called the pharmacologic effect; usually refers to the drug action on a receptor, enzyme, or other macromolecule; does not refer to the effect the drug has on the body |
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Term
| Nonspecific cellular responses |
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Definition
| responses that occur independently of cellular receptors, and are associated with other mechanisms, such as changing the permeability of cellular membranes, depressing membrane excitability, or altering the activity of cellular pumps |
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Definition
| a drug that produces a weaker, or less efficacious, response than an agonist |
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| a cellular protein macromolecule to which a medication binds in order to initiate its effects |
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| specificity of the binding means that drugs can be produced that are selective for specific types [and subtypes] of receptors; an interaction of a drug with a receptor elicits primarily one effect or response |
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Definition
| an interaction of the drug with preferentially one receptor class or a single receptor subtype |
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