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pharmaceutics
final
25
Science
Post-Graduate
05/01/2009

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Cards

Term
buffers
Definition
acetates, citrates, phosphate
Term
sweetners
Definition
sucrose, glycerol, sorbitol,
Term
viscosity inducing agents
Definition
cellulose derivatives, pvp, ionic polymers, sodium alginate
Term
antioxidants/chelating
Definition
ascorbic acid,BHT, EDTA, citric acid
Term
preservatives
Definition
benzoic acid and salts, sorbic acid and its salts
Term
fatty suppository bases
Definition
cocoa butter, fattibase, witepsol bases
Term
water soluble suppository bases
Definition
glycerinated gelatin, polyethylene glycols
Term
nonionic surfactants
Definition
most popular;not suceptibel to pH changes
Term
cationic surfactants
Definition
bactericidal properties
Term
aninonic surfactants
Definition
soluble in water and good o/w emulsifier; disagreeable taste and can be irritating
Term
vegetable derivative emlulsifying agents
Definition
acacia tragacanth, agar, pectin, carrageenan
Term
animal derivative emulsifying agents
Definition
gelatin, lanolin, cholesterol, lecithin
Term
semi-synthetic agents
Definition
methylcellulose, carboxymethylcellulose
Term
synthetic agents
Definition
carbopols
Term
coalescence
Definition
complete and irreversible separation and fusion of the dispersed phase
Term
creaming
Definition
occurs when dispersed oil droplets merge and rise to the top of an o/w emulsion
Term
phase inversion
Definition
change from a water-in-oil to an oil-in-water (or vice versa) emulsion
Term
Steam Sterilization
Definition
Temperature/pressure is usually 115.5⁰ to 126.5⁰C for 15 to 30 minutes
Term
Dry Heat Sterilization
Definition
Usually 150⁰ to 170⁰C for not less than 2 hours
Term
ashp risk level 1
Definition
Transferring a sterile drug product from a vial into a commercially prepared IV bag
Term
ashp Risk Level 2
Definition
Subdividing the contents of a bulk, sterile injectable (without preservatives) into single-dose syringes
Term
ashp risk level 3
Definition
Morphine injections made from powder or tablets
Term
USP low risk
Definition
Single transfers of sterile dosage forms, etc.
Term
USP medium level
Definition
Transfer of volumes from multiple ampuls or vials into a single final sterile container
Term
USP high risk
Definition
Dissolving nonsterile bulk drug and nutrient powders to make solutions, which will be terminally sterilized
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