Term
|
Definition
-dry substance composed of finely divided particles
-Lactose, PEG 3350 |
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Term
|
Definition
-agglomerates of powder particles
-coarse, better flow
-Mucinex Mini Melts |
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Term
|
Definition
-oral
-dusting
-insufflation
-sterile
-dentrifice
-douche |
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Term
|
Definition
-to be dissolved in water or foods
-effervescent
-ex.sodium bicarbonate |
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Term
|
Definition
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Term
|
Definition
| -powders to be blown onto the body |
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Term
| how to achieve a homogenous mix |
|
Definition
-uniform particle size and density
-particle movement (space)
-avoid segregation (demixing) |
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|
Term
| powder mixing on small scale |
|
Definition
-trituration
-spatulation (ointments)
-sifting (delump and mix) |
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|
Term
| use geometric dilution when ratio is |
|
Definition
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Term
|
Definition
| -solid dosage forms in which drugs is enclosed in a shell |
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Term
|
Definition
-2 piece
-gelatin and HPMC |
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Term
|
Definition
-1 piece
-gelatin shell
-most common |
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|
Term
|
Definition
-cellulose
-plant derived
-temp independent
-more stable then gelatin
-more expensive |
|
|
Term
| minor components of capsule shells |
|
Definition
-plasticizer (reduces rigidity)
-colorants
-opacifiers (TiO2, foundation)
-preservatives |
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Term
|
Definition
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Term
|
Definition
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|
Term
| 2 piece fill compositions |
|
Definition
-powders and granules
-coated beads/pellets (controlled release)
-combination products
-liquids
-semi-solids
-small tablet/capsules with diluents |
|
|
Term
| 1 piece fill compositions |
|
Definition
-liquids (solutions, suspensions)
-combination products
-semi solids |
|
|
Term
|
Definition
-bulk, aesthetics
-lactose,microcrystalline cellulose, starch |
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
| manufacture of 2 piece capsule shells |
|
Definition
-melt gelatin
-dip pins/pegs of desired shape/size
-trim and join together |
|
|
Term
|
Definition
-feed capsule
-rectify capsule
-separate capsule body/cap
-fill capsule body
-cap and seal
-eject
-wt, check, clean and polish
-print |
|
|
Term
| manufacturing techniques for 2 piece capsules |
|
Definition
-direct fill
-disk tamping
-dosator
-punch method
-semi auto machines |
|
|
Term
| manufacturing of 1 piece capsule products |
|
Definition
| -rotary die or plate molding designs |
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