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Three types of Medications used to treat anxiety and sleep disorders |
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Antidepressants Benzodiazepines Barbiturates |
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Withdrawal S/S of Sedatives, Hypnotics, Sedative Hypnotics |
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Life threatening, fever, psychosis, seizures, tachycardia, hypotension, muscle cramps, memory impairment, loss of appetite, auditory and visual disturbances, insomnia, agitation, anxiety |
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Major Types of Anxiety Disorders |
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Situational anxiety Generalized anxiety disorder (GAD) Panic disorder Phobias Obsessive-compulsive disorder Post-traumatic stress disorder |
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Nonpharmacologic Therapies to Cope with Anxiety |
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Cognitive behavioral therapy Counseling Biofeedback techniques Meditation |
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bind to GABA receptors increasing there effects (slowing neurotransmission) |
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Uses:anxiety, insomnia, szs, & alcohol withdrawal |
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Librium, Valium, Ativan, Versed |
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blocks the receptors from binding with the benzo BENZO ANTIDOTE |
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Romazicon works how fast? |
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IV over 30 seconds repeated every minute as needed |
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Highly addictive Withdrawal s/s are severe and can be fatal Overdose s/s-resp depression, hypotension, pin point pupils, & shock Avoid other sedatives IM can cause necrosis |
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Nonbenzodiazepines, Nonbarbiturate (CNS depressant) EX |
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Nonbenzodiazepines, Nonbarbiturate (CNS depressant) AX |
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Nonbenzodiazepines, Nonbarbiturate (CNS depressant) Use |
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Nonbenzodiazepines, Nonbarbiturate (CNS depressant) SE |
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mild nausea, dizziness, diarrhea, daytime drowsiness, amnesia, sleepwalking, ingesting carbohydrates while sleepwalking |
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Nonbenzodiazepines, Nonbarbiturate (CNS depressant) IMPS |
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works better if not used everyday Watch for over sedation |
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binds to serotonin and dopamine receptors and increases norepi metabolism |
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Decreases anxiety w/o causing sedation Less likely to cause dependency May take several weeks to be therapeutic |
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Natural hormone released from the pineal gland at night Tryptophan is converted to serotonin and then to melatonin Causes alertness and temperature to decrease, inviting sleep Levels vary with age |
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Agitation, excessive talking, elevated mood, grandiose thoughts Flight of ideas, constant movement, impulsive behavior Inflated self-esteem, racing thoughts, short attention span |
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Tricyclic Antidepressants Ax |
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blockmonoamine reuptake, intensifying the effects of norepi and serotonin |
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Tricyclic Antidepressants EX |
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Tricyclic Antidepressants SE |
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orthostatic hypotension, anticholineric effects, sedation, cardiotoxic, szs, hypomania, sexual dysfunction, HTN crisis |
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Tricyclic Antidpressants Nursing IMps |
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Usually given once a day at bedtime Watch for suicide DO NOT give with MAOIs-severe HTN from excessive adrenergic stimulation May take several weeks to be therapeutic Many drug interactions |
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decrease reuptake of serotionin into presynaptic nerve terminals |
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depression, OCD, panic dxs, bulimia nervosa |
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May take several weeks to be therapeutic Less SEs Don’t give with MAOIs-serotonin syndrome Do not discontinue abruptly |
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inhibit monoamine oxidase (terminates the actionof dopamine, norepi, epi, and serotonin) |
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orthostatic hypotension, HA, insomnia, and diarrhea |
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Lots of contraindications and interactions Watch for liver, renal, and blood dysfunctions May lower sz threshold |
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szs, fatigue, neuromuscular impairment, wt gain |
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MOOD STABILIZER THERAPEUTIC INDEX |
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Very narrow therapeutic index 0.6-1.4 Toxicity begins at 1.5 Death may occur at 2.5 |
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Lots of interactions Significant changes in Na intake can increase risk for toxicity Monitor renal function |
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insomnia, nervousness, anorexia, wt loss |
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Can cause dependency Monitor weight closely Report any ticks that develop Monitor EKG |
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ADHD NON CNS STIMULANTS EX. |
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ADHD-Non-CNS Stimulants IMPS |
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Often used in conjunction with another med Not very effective if used alone |
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Most common psychotic disorder |
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Most common psychotic disorder Manifests in men aged 15 to 24 years Manifests in women in aged 25 to 34 years |
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Hallucinations, delusions, or paranoia Strange and irrational behavior Severe depression
Alternating rapidly between extreme hyperactivity and stupor Attitude of indifference or detachment toward life activities Deterioration of personal hygiene and/or job or academic performance Withdrawal from social and interpersonal relationships |
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add on to normal behavior |
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subtract from normal behavior |
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schizo ass. with what receptro in the brain |
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Antipsychotic Med's General Info |
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Do not cure schizophrenia Are effective as long as the client takes the medication Have multiple undesirable side effects Selection of appropriate medication related to several factors |
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Conditions that may mimic the behaviors of schizophrenia |
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Drug use Brain neoplasm Infections Hemorrhage |
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Schizoaffective disorder characterizations |
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Distorted perceptions Hallucinations Delusions Extreme depression following these symptoms |
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Extrapyramidal Symptoms (EPS) |
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Tardive dyskinesia Acute dystonias Akathisia Stooped posture, shuffling gait Parkinsonism symptoms |
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Neuroleptic Malignant Syndrome (NMS) |
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Toxic reaction to therapeutic doses of antipsychotic drug |
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Neuroleptic Malignant Syndrome (NMS) s/s |
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Elevated temperature Unstable blood pressure Profuse sweating Dyspnea Muscle rigidity Incontinence |
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Typical Antipsychotic aka 1st gen |
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prevent dopamine and serotonin from binding to receptors |
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Typical Antipsychotic IMPS |
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Many SEs-EPS, etc May give with Cogentin |
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Cause less sedation and fewer SEs, but still can cause EPS |
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Atypical PYSCHOTICS AKA 2nd Gen ax |
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may block several receptors in the brain |
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Dopamine System Stabilizers EX |
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Dopamine System Stabilizers IMPS |
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