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Pharm - Thyroid
Pharm t5
27
Pharmacology
Graduate
04/05/2010

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Cards

Term
5 drugs causing hypothyroidism by inhibiting iodine transport:
Definition
1. potassium perchlorate (in xs)
2. thiocyanate
3. bromine
4. fluorine
5. lithium
Term
2 drugs causing imapired organificaiton and coupling of thyroid hormones:
Definition
1. thiamides
2. sulfonylureas
Term
2 drugs that cause inhibition of thyroid hormone synthesis:
Definition
1. Iodides
2. amioderone
Term
4 drugs taht induce hyperthyroidism":
Definition
1. Iodides
2. amiodarone (contains 37%iodine)
3. lithium
4. thyroid hormones
Term
tx for hypothyroidism: crude hormone from animal glands:
Definition
Dessicated thyroid (armour thyroid)
Term
levothyroxone:
Definition
T4, synthroid; for the tx of hypothyroidism or TSH supression
Term
3 drugs increase metabolism causing hypothyroidism:
Definition
1. rifampen
2. phynetoin
3. carbemazepine
Term
Liothyronine:
Definition
T3, cytomel
Term
synthetic t4/t3 in a 4:1 ratio -
Definition
Liotrix (Thyrolar)
Term
4 tx for myxedema coma:
Definition
1. T4
2. hydorcortisone
3. supportive; vent, glu, etc.
Term
thioamides are tx for:
Definition
hyperthyroidism
Term
2 thioamides:
Definition
propylthiouracil (PTU) & methimazole
Term
MOA for thioamides:
Definition
1. inhibits iodine oxidation
2. pervents T4 conversion to T3in periphery
Term
Iodides are tx for:
Definition
hyperthyroidism
Term
Iodides MOA:
Definition
decrease thyroid secretion and gland vascularity
Term
3 forms of Iodide:
Definition
1. lugol's solution
2. SSKI
3. sodium iodide
Term
2 indications for iodides:
Definition
1. thyrotoxicosis
2. preparing thyroid gland for surgery
Term
drug causes sialdentitis:
Definition
iodides
Term
adrenergic antagonists are tx for:
Definition
hyperthyroidism
Term
adrenergic antagonists MOA:
Definition
block the increased sympathetic activity caused by hyperthyroidism
Term
the preferred adrenergic antagonist:
Definition
Beta Blockers
Term
dilatazem is tx for:
Definition
hyperthyroidism
Term
lithium is tx for:
Definition
hyperthyroidism
Term
lithium MOA:
Definition
blocks hormone release and synthesis
Term
tx for thyroid strom:
Definition
thioamides and iodine; PTU prefered over methimazole due to peripheral effects
Term
preferred drug in pregnancy & hyperthyroidism:
Definition
PTU
Term
Radioactive Iodine is a tx for:
Definition
hyperthyroidism
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