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Pharm Test 5
Seizures, Coagulants, Hypertension
52
Pharmacology
Undergraduate 1
10/13/2011

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Cards

Term
What can an abrupt withdrawal precipitate in a patient/client diagnosed with a seizure disorder?
Definition
status epilepticus
Term
______________ are considered alterations in consciousness.
Definition
absence seizures
Term
How long does it typically take phenobarbital to reach therapeutic serum levels?
Definition
2-3 weeks
Term
What are the key teaching instructions that you would give a patient/client on phenytoin?
Definition
Need for: dental care
alternative contraception
observation of further seizure activity
importance of taking medications
obtaining lab levels
drug serum level
kidney function
liver enzymes
Term
You are caring for a patient who asks you if taking seizure medications will cure his seizure activity. Your best response is?
Definition
No, it will diminish the seizure activity not sure it.
Term
GABA effects potentially have what affect on anti epileptic drugs or (AED's)?
Definition
The GABA effects can alter seizure activity.
Term
You are caring for a patient who asks you why the doctor is placing him on 2 different anti epileptic drugs. Your best response is?
Definition
One drug may not be controlling his seizure activity and two will hopefully help further diminish the seizure activity.
Term
What is a physiological sign of a toxic level of phenytoin?
Definition
Nystagmus
Term
Patients who are on AED's (anti epileptic drugs) are discouraged from becoming pregnant because?
Definition
There is an increased incidence of teratogenesis.
Term
If a patient has discovred that there is availibility of a less expensive alternative to a drug they are taking should you advise them to switch immediately?
Definition
No they need to check with their provider first.
Term
If you are scheduling a patient for a lab draw for a AED drug level, what is the est time of day to do so?
Definition
early morning
Term
Which drugs are contraindicated to use with a patient/client on Tegretol (carbamazepine)?
Definition
MAOIs
Term
If an epileptic client is pregnant, what nutritional deficiency is she most prone to?
Definition
folate deficiency
Term
As with all medications (for the most part) patients/clients should be placed on what level of drug?
Highest
lowest
in between
Definition
Lowest and climb or add a different class of drug
Term
A patient has high alcohol blood levle. If he experiences seizures what type of medication should you administer as the nurse be prepared to administer?
Definition
lorazepam or Ativan
Term
What is the drug of choice for a clonic tonic and grand mal seizures?
Definition
carbamezepine (Tegretol)
Term
Gingival hypertrophy and weight loss are the main side effects of what anti epileptic drug?
Definition
ethosuximide
Term
What are the major signs and symptoms of eclampsia?
Definition
high blood pressure
headache
seizure activity
Term
What type of drug is zonisamide?
Definition
hydantoin
Term
When are seizures likely to occur after a person has stopped drinking alcohol?
Definition
1-3 days
Term
When you are looking up a drug and it states that the drug is a category X what does that mean?
Definition
Term
Normal clotting occurs in about _________ minutes.
Definition
6
Term
Fibrinolysis os the process of?
Definition
clot removal
Term
What lab test is used to evaluate the effectiveness of heparin? of warfarin?
Definition
heparin-aPTT
warfarin-PT/NR
Term
What is the antidote for heparin? for warfarin?
Definition
heparin-protamine sulfate
warfarin-vitamin k
Term
Warfarin takes how long to reach its maximum effect?
How long does it take to diminish the effects of warfarin?
Definition
Days
10 days
Term
Aspirin inhibits platelet aggregation by inhibiting what chemical compound?
Definition
thromboxane A2
Term
Glycoprotein IIb/IIIa blocks the final steps in what process?
Definition
platelet aggregation
Term
Lasiz (furosemide) lowers blood pressure by increasing what function in the kidney?
Definition
excretion of water and Na+ (sodium)
Term
How does stepped therapy work in treating a patient/client with hypertension?
Definition
Progressively increase the amount of the drug and adding a different class of drug.
Term
All antihypertensive can cause that side effect?
So what 2 vital signs should you make sure that you obtain prior to administering your hypertensives?
Definition
hypotension
blood pressure and pulse
Term
What is the unusual side effect experienced by a patient/client on an angiotensin-enzyme inhibitor or ACE?
Definition
dry, hacky cough
Term
You are caring for a patient/client who is taking Procardia (infedipine). He is back in to the clinic fo a B/P check. He also tells you he has been experiencing heartburn lately and has been taking OTC for it. You ask him specifically what OTC product has he been taking, because you know that his blood pressure medicine will inhibit what ion from working?
Definition
Anything with calcium in it because Procardia or nifedipine is a calcium channel blocker.
Term
Define hypertenstion.
Definition
A disease of the artrial blood vessels. Also known as high blood pressure.
Term
What disease processes have hypertension as a secondary effect?
Definition
Cushing's syndrome, hyperthyroidism, chronic renal disease.
Term
What does systolic pressure represent?
Definition
The force needed to eject blood out of the heart into the arteries of the body.
Term
What does diastolic pressure represent?
Definition
The relaxation of the heart and the fall of the pressure in the arteries of the body.
Term
Regulators of BP include?
Definition
Vasomotor center (air traffic controllers) in the medulla oblongata and baroceptors (spies) in the carotid artery and aorta.
Term
What hormones play an important role in the regulation of BP?
Definition
epinephrine, norepinephrine, ADH, renin-angiotensin-aldosterone system
Term
What class of family ends in "thyaride"?
Definition
Diuretic
Term
What class of drug end in "pril"?
Definition
ace inhibitor
Term
What class of drug ends in "sartan"?
Definition
ARBs
Term
What are ARBs?
Definition
angiotensin-inhibitor blockers, work by vasodilatation.
Term
What class of drug ends in "pines"?
Definition
Calcium channel blockers
Term
What class of drug ends in "olol"?
Definition
beta blockers
Term
What class of drug ends on "nitrate"?
Definition
nitroglycerin
Term
All seizures are not what?
Definition
convulsions
Term
A rapid increase in body temperature causes what type of seizure?
Definition
febrile
Term
What is the best time to check blood levels for antiseizure meds?
Definition
the early morning
Term
The solid, insoluble part of a blood clot is called what?
Definition
fibrin
Term
What is the antidote for heparin?
Definition
protamine sulfate, IM or IV
Term
What is the antidote for coumedin?
Definition
Vitamin K PO or IM
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