Term
| Tx with oral AMDs must continue for at least? |
|
Definition
| Two days after apparent cure |
|
|
Term
| Tx should be longer after apparent cure for what conditions? |
|
Definition
CNS infections (or any site with limited access)
Tuberculosis
Malaria |
|
|
Term
| Monitoring the antibiotic plasma concentration might be desirable if |
|
Definition
It is needed as a guide to dose (ex: CSF)
It is needed to avoid toxicity (ex: low TI) |
|
|
Term
|
Definition
| CLAVULANATE AND SULBACTAM |
|
|
Term
| INHIBITS DEHYDROPEPTIDASE-1 |
|
Definition
|
|
Term
|
Definition
| AMOXICILLIN + CLAVULANATE |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| THESE ALSO AFFECT MAMMALIAN CELLS |
|
Definition
AMPHOTERICIN B
CHORAMPHENICOL
KETOCONAZOLE |
|
|
Term
| very significant for drug resistance |
|
Definition
|
|
Term
|
Definition
| Clavulanic acid + Ticarcillin |
|
|
Term
| Therapeutic Uses of expanded spectrum penicillins? |
|
Definition
| Systemic gram (-) infections (especially pseudomonas aeruginosa) in hospitalized patients |
|
|
Term
| Oral forms of penicillin? |
|
Definition
| Pen V, Amoxicillin, Ampicillin, and oxacillin. |
|
|
Term
| What blocks renal excretion of penicillin? |
|
Definition
|
|
Term
| Repository preparations of Pen G (IM) |
|
Definition
Procaine - lasts 1-3 days
Benzathine - low doses for about 26 days |
|
|
Term
| What can be combined with antipseudomonal penicillins for higher activity against pseudomonas but cannot be combined with other penicillins? |
|
Definition
|
|
Term
| Name the first generation cephalosporins? |
|
Definition
| Cefazolin, Cephalexin[oral] |
|
|
Term
| Name the 2nd generation cephalosporins |
|
Definition
| Cefuroxime, Loracarbef[oral], Cefaclor(1st Gen like spectrum) |
|
|
Term
| Name the third generation cephalosporins |
|
Definition
| Ceftizoxime, ceftriaxone, cefixime[oral] |
|
|
Term
| Name the fourth generation cephalosporins |
|
Definition
|
|
Term
| Which Cephalosporins have beta-lactamase activity? |
|
Definition
| 3rd and 4th generation, although 3rd have less antistaph activity |
|
|
Term
|
Definition
| Imipenem + Cilastatin Broader spectrum than most B-lactams |
|
|
Term
|
Definition
| similar to carbapenem except little antigram (-) activity and it behaves more like an aminoglycoside |
|
|
Term
| Therapeutic uses of natural penicillins |
|
Definition
1. URI due to strep.
2. Prophylaxis before surgeries if history of Rheumatic fever or valve damage. |
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Term
|
Definition
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Term
|
Definition
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Term
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Definition
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