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Pharm Test 1- Anxiety and Insomnia
n/a
46
Nursing
Undergraduate 4
02/06/2010

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Cards

Term
This client is experiencing ___.

Apprehension
Worry, fear
Palpitations
SOB
Heartburn
Dry mouth
Excess Sweating
Definition
Anxiety
Term
Can we use barbiturates for anxiety?
Definition
NO! TOTALLY INAPPROPRIATE
Term
Name 5 Pharmacologic categories for anxiety.
Definition
1. Benzodiazepines
2. Antihistamines
3. Tricyclic Antidepressants
4. SSRI's
5. Herbal Meds
Term
All benzo's end in ___ or ___.
Definition
-am or -pam
Term
Name 4 Benzos.
Definition
1. Alprazolam (Xanax)
2. Diazepam (Valium)
3. Lorazepam (Ativan)
4. Temazepam (Restoril)
Term
What is the MOA of benzos?

They bind to ___ receptors and produce a calming effect on the ___.
Definition
GABA
CNS
Term
Benzodiazepines are ___ depressants.
Definition
CNS
Term
Name 5 adverse effects of benzos.
Definition
1. Respiratory depression
2. Dizziness
3. Drowsy
4. Ataxia
5. Confusion
Term
Teaching for benzos:

Can not drink ___ or ___.
Potential for ____
Definition
Alcohol or grapefruit juice
Dependence
Term
Benzos are pregnancy category __. They ___ the effects of birth control pills.
Definition
D; decrease
Term
Drug/Drug interactions with Benzodiazepines:

Can't take with ___, ___, ___.
Definition
Opioids, hypnotics, sedatives
Term
Drug/Drug interactions with Benzodiazepines:

Increased sedation with: ___, ___, ___, ___.
Definition
Antabuse
Kava Kava
Melatonin
Valerian
Term
Drug/Drug interactions with Benzodiazepines:

Decreased effects with ___ and excess ___.
Definition
Valproic acid (Depakote)
Excess caffeine

*Think soft drinks (acid and caffeine!)
Term
The antidote for Benzo OD is ___. It can bring back S/S of anxiety, though.
Definition
Romazicon
Term
True or False: If a client is experiencing respiratory depression while on Benzos, do we give them Romazicon?
Definition
It depends on how severe the RR depression is, and if we could try other approaches 1st.?
Term
How do antihistamines help anxiety?

Depress the ___; ___-generation __ receptor antagonists.
Definition
Depress the CNS
1st generation H1 receptor antagonists
Term
Name 2 antihistamines.

These are given __-__ mg IV or __.
Definition
1. Diphenhydramine (Benadryl)
2. Hydroxyzine (Vistaril, Atarax)

25-50 mg IV or IM
Term
Antihistamines can cause paradoxical ___ stimulation, especially in the ___.

S/S of this?
Definition
CNS; elderly

Restlessness, agitation, pulling at clothes. Wiggling in bed, can’t be still, anxious

Urinary retention/frequency, RR change, increased bronchial secretions
Term
Antihistamines can cause anticholinergic side effects. Name 4.
Definition
1. Dry mouth
2. Blurred vision
3. Constipation
4. Urinary retention
Term
Who would benefit from using antihistamines?
Definition
Insomnia, anxiety, allergic reactions
*Suspected abusers
Term
What is the safest class of anti-anxiety drug?
Definition
SSRI/SNRI
Term
Name 4 drugs for long-term anxiety treatment. (SSRI/SNRI's)
Definition
1. Paxil
2. Prozac
3. Zoloft
4. Lexapro
Term
Name 4 side effects of SSRI/SNRI's
Definition
1. Weight gain
2. Sexual dysfunction
3. Seizures
4. Serotonin Syndrome (Fever, agitated, high BP)
Term
S/S SSRI/SNRI OD:
Definition
Confusion
Restless
Tremors
Flaccidity
Term
Name 3 herbal/OTC meds for anxiety.

Which is tolerated best?
Definition
Melatonin
Valerian
Kava Kava

Valerian (Smells BAD!)
Term
High doses of melatonin can cause 3 problems.
Definition
HA, mental impairment, nightmares
Term
Kava Kava can induce a coma when used with ____.

It can cause ___ damage. (Yellow skin/nails)
Definition
Benzodiazepines

Liver
Term
Insomnia agents should be used cautiously in ___, ___, severe ___, ___ impairment
Definition
COPD, apnea, severe CHF, neuro impairment
Term
What 2 insomnia agents are CNS depressants and are meant to be short-term (__-__days)?
Definition
Ambien and Lunesta
7-10 days

When I asked a SHORT Mexican man,"Como ESTA?" He QUICKly said "BIEN"

lunESTA and amBIEN are SHORT term and QUICK acting.
Term
Ambien and Lunesta have ___ onset.
What does this mean for pt care?
Definition
Rapid
Give right before bed
Term
Name 4 side effects of Ambien and Lunesta.
Definition
Daytime sedation
Confusion
N/V
Depression
Term
Do not drink ___ with Ambien/Lunesta.

In the elderly it can cause ___ and ___.

It can also cause ___-term memory loss and sleep ____, etc.
Definition
Alcohol

Aggression and combativeness

Short-term; sleep-walking
Term
What is the safest drug for insomnia?
Definition
Rozerem

Sleep in a bed of roses with Rozerem
Term
Rozerem is safe for ___ term use and less likely to be ___ or cause irregular ___ in women.
Definition
Long-term
Abused
Menstruation
Term
Why is it important for the nurse to know secondary causes of insomnia?
Definition
You need to treat the underlying problem, hopefully with non-pharm approaches
Term
What 4 things can cause secondary insomnia?
Definition
Drugs
Medical D/O
Poor sleep hygeine
Stressful situation
Term
___ can keep patients from reaching deep sleep.
Definition
Alcohol
Term
What type of secondary insomnia does this refer to?

Amphetamines, cocaine, alcohol, tobacco
CORTICOSTEROIDS, sympathomimetics, caffiene, antidepressants
Definition
Drugs
Term
What type of secondary insomnia does this refer to?

Dementia, anxiety, epilepsy, Parkinson's, Tourette's, psychosis, migraines, asthma, pain, apnea, COPD, GERD, hyperthyroid
Definition
Medical D/O
Term
What type of secondary insomnia does this refer to?

Noisy, light, large meals, exercise before bed, partner snores/moves
Definition
Poor sleep hygiene
Term
What type of secondary insomnia does this refer to?

Marriage, divorce, deatch, disease, stressful job
Definition
Stressful situation
Term
What phase of sleep concerns the actual "dreaming?" Patients are susceptible to be ____ during this phase.
Definition
REM; awoken
Term
This disease skips sleeps stages and goes directly into __-__ minutes of deep sleep. It is managed with ___ drugs.
Definition
Narcolepsy
15-20 minutes
Stimulant (Amphetamines, Methylphenidate)
Term
When is the only scenario of anxiety in which you would use drugs before non-pharm?
Definition
When a patient is 'dangerous' or has 'scary' vital signs
Term
What is the primary side effect to look for in Ativan?
Definition
Respiratory depression
Term
What is the primary side effect to watch for in Zolpidem (Ambien, Tovalt)?
Definition
Respiratory depression
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