Shared Flashcard Set

Details

pharm - smoking
pharm t6
28
Pharmacology
Graduate
04/22/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
onset of nicotine withdrawal occurs within and can last:
Definition
24h and can last days to wks
Term
nicotine MOA:
Definition
ganglionic cholinergic receptor agonist leading to stimulation and depression of CNS & PNS
Term
effects of low dose nicotine:
Definition
hightened alertness and increased cognitive fxn
Term
effects of high dose nicotine:
Definition
stimulates the reward sys in the limbic system of the brain
Term
among those trying to quit who should be recommended behavior modification therapy?
Definition
everone
Term
contraindications to nicotine replacement therapy:
Definition
1. hypersensitivity
2. post MI
3. arrhythmia
Term
optimal use of nicorette
Definition
chew on a schedule (chew and park)
Term
which is the 24h patch?
Definition
nicoderm CQ
Term
SE of the patch
Definition
insomnia
Term
max dose for nasal spray:
Definition
5doses/hr or 40doses/day
Term
which NRTs are RX only:4
Definition
1. nasal spray
2. inhaler
3. bupropion
4. chantix
Term
DA reuptake inhibitor:
Definition
bupropion
Term
when to start bupropion
Definition
1-2wks before quiting
Term
bupriopion contraindicated in:
Definition
1. epilepsy
2. eating d/o
3. used wn 14 d of MAOI
Term
FDA warning for chantix:
Definition
depression, aggitation, behavioral changes, suicide
Term
which is NOT FOR COMBO USE:
Definition
chantix
Term
when to start chantix:
Definition
1wk before quit date
Term
SE abnormal dreams:
Definition
chantix
Term
2 2nd line therapies for smoking cesation:
Definition
1. clonodine
2. nortriptyline
Term
clonodine come in which form?
Definition
patch
Term
abruptly d/c clonidine leads to:
Definition
1. rebound HTN
2. hypotension
Term
contraindications to clonidine:
Definition
1. MAOI wn 14d
2. elderly
Term
abruptly d/c nortriptyline leads to:
Definition
rebound HTN/hypotension
Term
nortriptyline contraindications:
Definition
MAOI wn 14d
Term
start low go slow
Definition
nortriptyline
Term
which is hwlpful for cessation & depression
Definition
bupropion
Term
mainstay of cessation therapy in adolecents:
Definition
behavioral modification not NRT
Term
why would stopping smoking increase concentrations of drugs?
Definition
smoking induces CYP enzymes; stopping will < drug metabolism
Supporting users have an ad free experience!