Term
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Definition
| androgen, has effects on spermatogenesis, 2ary sex characteristics, bone mass, epiphyseal closure, libido and sexual function, sebum, balding, erythropoietin
ROA: transdermal patch, oral/buccal, depot. NOT oral.
uses: hypogonadism, replacement, female breast cancer, hereditary angioedema, debilitation, anemias (replaced by CSFs) |
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Term
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Definition
| testosterone can be converted by 5a-reductaseto DHT. Higher affinity for testosterone receptors. |
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Term
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Definition
| Testosterone prep delievered by oral or buccal mucosa. uses: hypogonadism |
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Term
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Definition
| nonsteroidal antiandrogen mech: competitive antagonist at androgen receptor.
Give with leuprolide to prevent GnRH secretion.
SE: gynecomastia, N/V, hepatitis
uses: BPH, prostate cancer, hirsutism/virilism in women, hypersexuality, precocious puberty in boys (gonadotropin-independent) |
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Term
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Definition
| competitive inh of 5a-reductase, which is required for activity of some tissues (like prostate)
SE: can affect male fetal sexual development (X: pregnancy)
uses: BPH, prostate cancer, hirsutism/virilism in women, hypersexuality, precocious puberty in boys (gonadotropin-independent) |
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Term
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Definition
| natural estrogen, full agonist
uses:replacement, contraception, cancer treatment
ROA: transdermal, micronized, pellet, vaginal cream |
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Term
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Definition
| natural estrogen, full agonist
uses:replacement, contraception, cancer treatment |
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Term
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Definition
| semi-synthetic steroidal estrogens, full agonist
uses:replacement, contraception, cancer treatment |
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