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Pharm Quiz #4
Rhinitis
33
Pharmacology
Graduate
02/09/2012

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Term
Synonym for Seasonal
Definition
Intermittent
Term
Synonym fro Perennial
Definition
Persistent
Term
Disease often associated with Rhinitis
Definition
Viral URI
Term
What percent of population is affected by Rhinitis?
Definition
100%
Term
What ages are the highest incidence of Allergic Rhinitis in?
Definition
15-25 years
Term
Predisposing Factors for AR?
Definition
Asthma, atopic dermatitis, family hx, exposure to second hand smoke, occupational/environmental exposures, early introduction of formula and foods
Term
FEF25-75
Definition
Forced Expiratory Flow average from 25% to 75%
Term
Symptoms of AR
Definition
rhinnorhea, nasal obstruction, nasal itching, sneezing
Term
Comorbities of AR
Definition
asthma, conjuctivitis, rhinosinusitis
Term
Which Ig is mediated after allergen exposure?
Definition
IgE
Term
What pollens are associated with Spring?
Definition
Tree pollens
Term
What pollens are associated with Spring to late summer?
Definition
grass pollens
Term
What pollens are associated with late summer to early fall?
Definition
weed pollens
Term
Which T helper cells are produced to make IgE?
Definition
TH2 cells
Term
What is the pathophysiology of Sensitization?
Definition
IgE produced directed at protein
Mast cells become present
Term
What is the pathophysiology of Exposure?
Definition
Inhaled allergic protein
Cross the mucus membrane
IgE binded on mast cell to trigger response
Term
Mast cell degranulates with what mediators?
Definition
histamine release
arachidonic acid metabolites synthesized
Term
Time when late phase response occurs
Definition
4-8 hours after exposure
Term
Predominant source of histamine comes from?
Definition
Basophils and some from eosinophils
Term
Diagnosis signs from the eyes
Definition
Allergic Shiners and Watery eyes
Term
Diagnosis signs from the nose
Definition
Transverse nasal crease
Pale blue, edematous turbinates
clear, watery nasal discharge
Term
What does the TM do during the Allergic reaction
Definition
TM is either retracted or bulging
Term
What angle to prick skin for allergic testing
Definition
45 to 60 degrees
Term
what angle to puncture skin for allergic testing
Definition
90 degrees
Term
Which control is dermagraphism- physical uticaria?
Definition
Positive negative control
Term
Which control is a medication reaction or hypoactive skin?
Definition
Negative Positive Control
Term
No reaction or 1-3mm wheal grade?
Definition
0
Term
Erythema with 3mm wheal grade?
Definition
1+
Term
Erythema with 5mm wheal grade?
Definition
2+
Term
Erythema with 7-10mm wheal grade?
Definition
3+
Term
Erythema with >10 mm wheal grade?
Definition
4+
Term
Erythema with >10mm wheal psuedopods grade?
Definition
5+
Term
Perennial Allergens
Definition
Dust mites
Animal dander Cats> Dogs
Cockroaches
Mold
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