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pharm quiz 3
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61
Pharmacology
Undergraduate 2
03/04/2013

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Term
celecoxib
Definition
cox 2 selective inhibitor
Term
fluticasone
Definition
intranasal glucocorticoid
Term
pseudoephedrine
Definition
a decongestant
Term
dxm
Definition
otc antitussive
Term
h1
Definition
histamine receptors involved in allergies
Term
h2
Definition
histamine receptors that cause acid secretion
Term
albuterol
Definition
a beta2 agonist
Term
naloxone
Definition
a mu and kappa receptor antagonist
Term
zanaflex
Definition
a centrally actinguscle relaxant
Term
cortisone
Definition
commonly used as steroid injection at site of inflammation
Term
loratidine
Definition
h1antagonist that is second generation
Term
codeine
Definition
a narcotic antitussive
Term
cromolyn
Definition
mast cell inhibitor
Term
aspirin
Definition
nonselective cox inhibitor
Term
diphenhydramine
Definition
h1 antagonist that is 1st gen
Term
bechlomethasone
Definition
an inhaled steroid, doesn't stop attacks in progress. is preventative.
Term
acetominophen
Definition
drug that is an antipyretic and analgesic only
Term
guaifenesin
Definition
an expectorant
Term
epinephrine
Definition
indicated for anaphylaxis
Term
morphine
Definition
a mu and kappa receptor agonist
Term
fosamax
Definition
indicated for osteoporosis
Term
inhaled pulmonary drugs
Definition
have immediate onset of action
Term
nebulizer
Definition
vaporized liquid into mist pulmonary drug
Term
allergic rhinitis
Definition
sneezing, nasal congestion, watery eyes, aka hay fever. inflammation of nasal mucosa. from pollen, mites, dust, molds
Term
histamine, prostaglandins, leukotrienes
Definition
mediators in inflammation
Term
salmerterol
Definition
beta agonist with a long-25mins-onset of action but a longer duration of action than albuterol
Term
cromolyn
Definition
prevent asthma attacks. very safe. prevents mast cells from releasing histamine
Term
prednisone
Definition
oral steroid, prototype, reduces inflammation. for acute/severe inflammation. much worse se's than inhaled/injected
Term
oral steroids
Definition
side effects include weight loss/gain, osteoporosis, elevated blood glucose, deposits of fat in back of neck, moon face, jitteryness
Term
antihistamines
Definition
h1 receptor antagonists, can cause sedation, most common use for allergies. diphenhydramine, loratadine, fexofenadine. (benadryl, allergra, claritin)
Term
rhinitis
Definition
intranasal glucocorticoids are indicated for?
Term
phenylephrine
Definition
becoming more popular as decongestant. less cardiac side effects.
Term
oxymetazoline
Definition
aka afin. intranasal sympathomimetic. faster onset of action than pseudoephedrine. se-rebound congestion. dont use more than 3-5 days
Term
antitussives
Definition
suppress cough reflex
Term
expectorants
Definition
cough facilitator, reduce thickness and increase bronchial secretions. allows more productive cough.
Term
mucolytic drugs
Definition
prescription drugs that break up mucous. for COPD, cystic fibrosis.
Term
anaphylaxis
Definition
decreased bp, difficulty breathing, itching, hives. histamine release-->histamine interacts with h1 receptors which causes vasodilation=drop in bp
Term
nociceptors
Definition
in periphery, detect pain
Term
substance P
Definition
cns neurotransmitter that aids in transmission of pain sensation
Term
endorphins
Definition
endogenous opiods. help prevent pain sensation. interact with substance p
Term
prostaglandins
Definition
chemicals produced after tissue injury.
Term
eicosinoids
Definition
mediators of pain and inflammation
Term
arachidondic acid
Definition
a substance found in cell membranes. used to make PGs
Term
cox1
Definition
enzyme produces pgs involved in plately aggregation or blood clotting. also involved in producing the PGs that protect lining of the stomach
Term
cox2
Definition
enzyme involved in forming the pgs that cause pain and inflammation
Term
GI bleeding
Definition
main SE of NSAIDs
Term
cox 2 inhibitors
Definition
have no GI SEs.
Term
naproxen sodiumn
Definition
nsaid with a long 1/2 life. good anti inflammatory. don't have to dose frequently
Term
acetaminophen
Definition
not a NSAID. not for inflammation. drug of choice for fever in kids
Term
opiod narcotic
Definition
drug that produces analgesia and depresses cns to cause sedation, for severe pain.
Term
respiratory depression, nausea and vomiting
Definition
opiods can interact with mu and kappa to also cause adverse reactions like
Term
zanaflex, flexeril, valium
Definition
3 centrally acting muscle relaxants
Term
botulinum
Definition
works at neuromuscular junction to relax muscles. blocks ach release
Term
osteoporosi
Definition
bone breakdown is greater than bone formation.
Term
osteoclast; osteoblasts
Definition
in osteoporosis, ____s become more active than ____
Term
lack of exercise, obesity, age, menopause, poor nutrition
Definition
risk factors for osteoporosis
Term
estrogen
Definition
___ limits osteoclasts activity (in women)
Term
osteoarthritis
Definition
considered "old age" arthritis. wear and tear. associated with pain and inflammation. one can get breakdown in the hyaline cartilage that can lead to pain
Term
rhematoid arthritis
Definition
is an autoimmune condition in which your immune system attacks your joints
Term
treatment for osteoarthritis
Definition
includes nsaids, cox2 inhibitors, acetaminophen, sometimes antidepressants. dietary-glucosamine sulfate, chondroitin sulfate (both promote cartilage repair adn can be combined)
Term
rheumatoid arthritis treatment
Definition
includes nsaid, cox 2 inhibitors, corticosteroids(even oral; help with inflammation, but can be immunosuppressant), gold salts.
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